Mechanical Maturation of Human Dermal Fibroblast-laden Microporous Annealed Particle Scaffolds During Long-term In Vitro Culture [0.03%]
人真皮成纤维细胞包封微多孔颗粒支架的长期体外培养中的机械成熟化研究
Claudia Daboin,Ethan Nicklow,Donald R Griffin
Claudia Daboin
The use of biomaterials to model diseases and tissues in vitro has updated our understandings of cellular processes through the inclusion of a 3D microenvironment that better mimics physiological conditions. A major limitation that remains ...
Gadolinium nanoparticle-enhanced, radiopaque, and resorbable inferior vena cava filters for improved in vivo applications [0.03%]
用于改进体内应用的钆纳米颗粒增强型、可显影且可降解的下腔静脉滤器
Erin Marie San Valentin,Jossana Damasco,Marvin Bernardino et al.
Erin Marie San Valentin et al.
Previous studies demonstrated that poly-p-dioxanone (PPDO)-based absorbable inferior vena cava filters (IVCFs) infused with high-Z nanoparticles enhance long-term radiopacity without compromising filter integrity and safety. This study expl...
Comparison of Biofilm-Degrading Activities of Two Glycoside Hydrolase Family 20 Enzymes against Clinical and Veterinary β-1,6-poly-N-acetyl-D-glucosamine-dependent Staphylococcus aureus Isolates [0.03%]
两种糖基水解酶家族20酶对临床和兽医β-1,6-聚N乙酰-D-葡萄糖胺依赖型金黄色葡萄球菌分离株的生物膜降解活性比较分析
Andrei Nicoli Gebieluca Dabul,Lorgio Victor Bautista Samaniego,Anelyse Abreu Cortez et al.
Andrei Nicoli Gebieluca Dabul et al.
Biofilms shield microbial communities from various environmental threats, including antimicrobial agents. Such protection renders bacterial cells within biofilms more resistant to antimicrobial agents than their planktonic counterparts. Deg...
Single-cell-pore-sized 3D Printed Scaffolds for Retinal Pigment Epithelial Cell Therapy [0.03%]
用于视网膜色素上皮细胞治疗的单细胞孔大小的3D打印支架
Hang Liu,Daniel Wong Soo Lin,Bhav Harshad Parikh et al.
Hang Liu et al.
Cell therapy is one of the most promising methods to treat retinal degenerative diseases, and crucial to its success is optimizing biomaterials to facilitate the delivery of retinal pigment epithelial (RPE) cells. This study explores the ap...
Subcellular two-pronged targeting therapeutics: disrupting mitochondria-endoplasmic reticulum communication in inflammatory disorders [0.03%]
亚细胞双重靶向疗法：在炎症性疾病中干扰线粒体-内质网通讯
Jianheng Ren,Yuanyi Hua,Zhumei Liao et al.
Jianheng Ren et al.
Researchers have made significant efforts to develop mitochondria or endoplasmic reticulum (ER)-targeting strategies to regulate cellular signaling cascades in inflammatory diseases. Although ER and mitochondria function relatively independ...
Design and Evaluation of Cationic Bottlebrush Polymers for Advanced Messenger RNA Therapeutics [0.03%]
用于先进mRNA疗法的阳离子支链聚合物的设计与评估
Alessia Filippini,Hu Zhang,Matthias Zadory et al.
Alessia Filippini et al.
Messenger RNA (mRNA) therapeutics are promising tools for vaccines, protein replacement, and cancer immunotherapy, but effective delivery systems are crucial to protect mRNA and ensure cellular uptake. Cationic polymers have gained attentio...
Corrigendum to "Copper-doped layered double hydroxides co-deliver proteins/drugs for cascaded chemodynamic/immunotherapy via dual regulation of tumor metabolism" [Acta Biomaterialia 2025, 195, 350-362] [0.03%]
“铜掺杂层状双氢氧化物协同递送蛋白质/药物用于级联化学动力免疫治疗并通过双重调节肿瘤代谢”一文的勘误 [Acta Biomaterialia 2025, 195, 350-362]
Gaoming Li,Zhiqiang Wang,Yunqi Guo et al.
Gaoming Li et al.
Published Erratum
Acta biomaterialia. 2025 Oct 16:S1742-7061(25)00544-6. DOI:10.1016/j.actbio.2025.07.047 2025
Virus-inspired nanocages potentiate glioblastoma sonochemotherapy via structure-function mimicry [0.03%]
病毒启发的纳米笼通过结构功能模拟促进胶质母细胞瘤声化学疗法
Xiaohang Liu,Jinyuan Ma,Yuhao Zhang et al.
Xiaohang Liu et al.
Sonochemotherapy has emerged as a promising strategy for glioma treatment through synergistic therapeutic effects and reduced systemic toxicity. Nevertheless, clinical translation remains constrained by the hypoxic tumor microenvironment, a...
In situ pro-regenerative and repair capabilities of human umbilical mesenchymal stem cells and collagen hydrogel complex in mice with thin endometrium [0.03%]
人脐带间充质干细胞和胶原水凝胶复合物在小鼠薄子宫内膜在位成瘤及修复能力研究
Mingye Chen,Junjie Tang,Binfa Liang et al.
Mingye Chen et al.
The increasing prevalence of refractory thin endometrium (TE) is a serious issue affecting women's reproductive health. Human umbilical cord-derived mesenchymal stem cells (huMSCs) have shown therapeutic potential for TE. However, their cli...
Ion-Mediated Progressively Stiffening Hydrogels for Vascularized Bone Regeneration [0.03%]
离子介导的渐进性硬化的水凝胶用于血管化骨再生
Wenhuan Bu,Jonathan I Dawson,Richard O C Oreffo et al.
Wenhuan Bu et al.
The extracellular matrix (ECM) of tissues progressively changes its mechanical properties in processes such as tissue development, repair, and disease progression. While stiffness has become a key design parameter of biomaterials, most synt...