Unpacking the black box - a questionnaire study of how medical journals identify and manage conflicts of interest of editors and peer reviewers [0.03%]
拆解“黑箱”——关于医学期刊如何识别和管理编辑及同行评审者利益冲突的问卷调查研究
Christoffer Bruun Korfitsen,Helena Van Beersel Krejčíková,Camilla Hansen Nejstgaard et al.
Christoffer Bruun Korfitsen et al.
Objectives: To describe how medical journals identify and manage conflicts of interest of editors and peer reviewers, how policies are enforced, and whether practices are concordant with policies. ...
On the importance of multiple aspects of cluster validation in multimorbidity research [0.03%]
论多维聚类验证在多重疾病研究中的重要性
Nikolaj Olerud Holm,Anne Frølich,Helle Gybel Juul-Larsen et al.
Nikolaj Olerud Holm et al.
How should covariates be handled in randomized trials? Empirical evidence from 50 trials and recommendations for practice [0.03%]
如何在随机试验中处理协变量？来自50项试验的经验证据及实践建议
Yulin Shao,Liangbo Lyu,Menggang Yu et al.
Yulin Shao et al.
Background and objective: Covariate adjustment can improve precision and power in randomized clinical trials and is recommended by major regulatory agencies. However, there is limited empirical evidence on how different a...
Equity, diversity, and inclusion in pivotal medical device clinical investigations: a scoping review of studies published in the past 5 years [0.03%]
过去五年发表的枢关性医疗器械临床试验中有关公平、多样性和包容性的综述研究
Maria Luisa Buzelli,Shoba Dawson,Declan Devane
Maria Luisa Buzelli
Objective: Equity, diversity, and inclusion (EDI) considerations are increasingly emphasised in clinical research, yet their integration within pivotal medical device investigations remains unclear. This scoping review ma...
Trial-design-aware funnel plot for publication bias assessment with non-inferiority or equivalence objectives [0.03%]
考虑试验设计的非劣效性和等效性临床试验发表偏倚漏斗图绘制方法
Xing Xing,Lifeng Lin,Mohammad Hassan Murad et al.
Xing Xing et al.
Background: Funnel plots are the most widely used graphical tool for assessing publication bias (PB) in meta-analyses of superiority trials. However, conventional funnel plots are not directly applicable to non-inferiorit...
Rethinking Methodological Appraisal in Overviews of Systematic Reviews: A Participatory Validation Framework [0.03%]
系统评价的评价：一种参与性验证框架
Clovis Mariano Faggion Jr,Paul M H Dummer,Venkateshbabu Nagendrababu
Clovis Mariano Faggion Jr
Background: Overviews of systematic reviews, or umbrella reviews, synthesize evidence across related research questions and inform clinical practice, policy, and research prioritization. A core component of overviews is t...
The use of variable selection in clinical prediction modelling for binary outcomes: a systematic review [0.03%]
逻辑回归模型中变量选择的系统评价及meta分析：二分类结局临床预测模型为例
Xinrui Su,Gareth Ambler,Nathan Green et al.
Xinrui Su et al.
Objective: Clinical prediction models are valuable tools that can support medical decision-making. Concise and interpretable models are more likely to be adopted in clinical practice, therefore appropriate selection of pr...
The suboptimal methodological quality of non-Cochrane reviews on hyoscine butylbromide to shorten labour duration raises concerns about their conclusions: a meta-research study [0.03%]
次优的方法质量引发了对非Cochrane系统评价中氢溴酸东莨菪碱缩短分娩时间的结论的担忧：一项元研究
Loukia M Spineli,Anna Bludau,Patricia Könneker et al.
Loukia M Spineli et al.
Objective: Hyoscine butylbromide (HBB) is commonly used off-label in labour wards. However, a Cochrane review raised concerns about the quality of evidence on HBB in childbirth, leading to the WHO's disapproval of HBB for...
Integrating Environmental Impacts into Economic Evaluation of Health Interventions: Moving Beyond Isolated Metrics [0.03%]
将环境影响融入卫生干预措施的经济评估：超越孤立指标
Mourgues Charline,Bourguignon Nathalie,Amakoué Yrkamba Bienvenu
Mourgues Charline
Engaging policymakers in the development of clinical practice guidelines: a global survey of current practice in guideline development [0.03%]
临床实践指南中政策制定者参与现状的全球调查报告及相关对策研究
Samantha Chakraborty,Viona Riskikallail,Anneliese Synnot et al.
Samantha Chakraborty et al.
Background and objectives: Implementation of clinical practice guidelines (guidelines) is enhanced by engaging stakeholders during guideline development. While policymakers are recognised as key stakeholders in guideline ...