Edith Ginika Otalike,Mike Clarke,Farjana Akhter et al.
Edith Ginika Otalike et al.
Objective: To systematically identify and synthesize methodological guidance for conducting IPD-MAs of randomized trials and observational studies, to inform the development of a critical appraisal tool for reports of IPD...
The RoB-VE Project: Introduction to a methodological initiative to improve risk-of-bias assessment and reporting in vaccine effectiveness research [0.03%]
ROB-VE项目:改善疫苗效果研究偏差风险评估和报告的方案介绍
Cassandra Laurie,Pablo Alonso Coello,Ivan D Florez et al.
Cassandra Laurie et al.
Background: Vaccine effectiveness (VE) studies are essential for informing immunization policy and public health decision-making. However, the observational nature of most VE studies introduces unique methodological chall...
David A Savitz,Neil Pearce,Kenneth J Rothman
David A Savitz
Hill's list of considerations for assessing causality, proposed 60 years ago, became a landmark in the interpretation of epidemiologic evidence. However, it has been and continues to be misused as a list of causal criteria to be scored and ...
GRADE guidance 44: Strategies to enhance the utilization of randomized and non-randomized studies in evidence syntheses of health interventions [0.03%]
GRADE指南第44号:在卫生技术干预证据综合中增强随机及非随机研究利用性的策略
Carlos A Cuello-Garcia,Rebecca L Morgan,Nancy Santesso et al.
Carlos A Cuello-Garcia et al.
Background and objectives: Ideally, guideline developers and HTA authors base intervention decisions on randomized controlled trials (RCTs). However, relying solely on RCTs is uncommon, especially for public health interv...
Discrimination, calibration, and variable importance in statistical and machine learning models for predicting overall survival in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors [0.03%]
用于预测免疫检查点抑制剂治疗的晚期非小细胞肺癌患者总体生存率的统计和机器学习模型中的歧视、校准和变量重要性
Lee X Li,Ashley M Hopkins,Richard Woodman et al.
Lee X Li et al.
Background and objective: Prognostic models can enhance clinician-patient communication and guide treatment decisions. Numerous machine learning (ML) algorithms are available and offer a novel approach to predicting survi...
Approaches for reporting and interpreting statistically nonsignificant findings in evidence syntheses: A systematic review [0.03%]
系统评价中统计学阴性结果的报告和解释方法:一项系统综述
Amin Sharifan,Andreea Dobrescu,Curtis Harrod et al.
Amin Sharifan et al.
Objective: To systematically review approaches for reporting and interpreting statistically nonsignificant findings with clinical relevance in evidence synthesis, and to assess their methodological quality and the extent ...
Including nonrandomized evidence in living systematic reviews: lessons learned from the COVID-NMA initiative [0.03%]
COVID-NMA项目谈在动态系统评价中纳入非随机证据的方法学挑战与经验教训
Hillary Bonnet,Julian P T Higgins,Anna Chaimani et al.
Hillary Bonnet et al.
Background: Randomized controlled trials (RCTs) are more likely to be included in evidence syntheses of health interventions due to their methodological rigor. However, the integration of nonrandomized studies (NRSs) may ...
Use of structured tools by peer reviewers of systematic reviews: a cross-sectional study reveals high familiarity with PRISMA but limited use of other tools [0.03%]
系统评价同行评议者使用结构化工具的情况:横断面研究发现熟悉PRISMA但其他工具使用较少
Livia Puljak,Sara Pintur,Tanja Rombey et al.
Livia Puljak et al.
Objective: Systematic reviews (SRs) are pivotal to evidence-based medicine. Structured tools exist to guide their reporting and appraisal, such as PRISMA and AMSTAR. However, there is limited data on whether peer reviewer...
Guideline Organizations' Guidance Documents Paper 4: Interest-holder engagement [0.03%]
指南制定机构的文件第四部分——利益攸关者参与
Joanne Khabsa,Vanessa Helou,Hussein A Noureldine et al.
Joanne Khabsa et al.
Introduction: Interest-holder engagement is increasingly recognized as essential to the relevance and uptake of practice guidelines. "Interest-holders" are groups with legitimate interests in the health issue under consid...
A Scoping Review of Critical Appraisal Tools and User Guides for Systematic Reviews with Network Meta-Analysis: Methodological Gaps and Directions for Tool Development [0.03%]
一项关于系统评价网络 meta分析批判性评价工具和用户指南的范围性综述:方法上的缺口及工具开发方向
K M Mondragon,C S Tan-Lim,R Jr Velasco et al.
K M Mondragon et al.
Background: Systematic reviews (SR) with network meta-analyses (NMA) are increasingly used to inform guidelines, health technology assessments, and policy decisions. Their methodological complexity, as well as the difficu...