Many multicenter randomized controlled trials do not account for center effect: a methodological review [0.03%]
多中心随机对照试验未纳入中心效应的因素:系统综述
Mohamad Ossman,Primael Megninou,Florian Lejeune et al.
Mohamad Ossman et al.
Objective: Multicenter randomized controlled trials are considered the gold standard for evaluating medical interventions, yet they raise important methodological challenges related to center effects. We aim 1) To assess ...
Patient Acceptability of the Modified Zelen Approach to Randomized Trials - A Survey of the CAPS THA Cohort [0.03%]
CAPS髋关节置换患者群体对改良Zelen随机临床试验设计的接受度调查
Nicole Bryant,Brent Lanting,Trevor Birmingham et al.
Nicole Bryant et al.
Background and objectives: Randomized controlled trials (RCTs) are the gold standard for evaluating interventions, but when comparing established care pathways, informed consent processes may alter usual preference-relate...
Corrigendum to SPICE-GRADE: simultaneous processing of indirect causal evidence in complex pathways using GRADE - an exploratory case study. [Journal of Clinical Epidemiology, 194C (2026) 112219] [0.03%]
SPICE-GRADE校正:复杂途径中同时处理间接因果证据的GRADE方法——探索性病例研究
Prashanti Eachempati,Gordon Guyatt,Per Olav Vandvik et al.
Prashanti Eachempati et al.
Published Erratum
Journal of clinical epidemiology. 2026 Jun 29:197:112369. DOI:10.1016/j.jclinepi.2026.112369 2026
Small numbers of clusters in cluster randomised trials: a scoping review of problems and proposed solutions [0.03%]
分组随机试验中少量分组集群的问题及解决方案的综述研究
Olivier Quintin,Jessica Kasza,Nathan Davies et al.
Olivier Quintin et al.
Background and objective: Cluster randomised trials (CRTs) are commonly used to evaluate health service interventions, quality improvement programmes or public health initiatives that are implemented at a regional or orga...
What's the Meta Now? More Updates on the Problems with Systematic Reviews [0.03%]
系统综述问题的更多更新:“元”是什么?
Lesley Uttley,Yuliang Weng,Louise Falzon
Lesley Uttley
Background: Systematic reviews are intended to provide trustworthy evidence synthesis, yet previous iterations of this living review have identified numerous recurring problems in their conduct and reporting. This article...
A scoping review of guidance on sharing trial results with patients and the public finds inconsistent recommendations and limited methodological development [0.03%]
一项关于向患者和公众共享试验结果的指导性文件的系统评价发现各指南间的建议不一致且缺乏严谨的方法学发展
Sanjana Choudhury,Gary S Collins,Charlotte Albury et al.
Sanjana Choudhury et al.
Objectives: To identify, analyse and summarise existing guidance on sharing trial results with patients and the public and to provide recommendations for developing a high-quality reporting guideline that is user-friendly...
Patterns of social determinants of health and their associations with health indicators: A latent class analysis [0.03%]
健康社会决定因素模式及其与健康指标之间的关联性:潜在类别分析
Jae-Yung Kwon,Ava Mehdipour,Mathilde Verdam et al.
Jae-Yung Kwon et al.
Objective: Social determinants of health (SDOH) are unevenly distributed and frequently co-occur, contributing to persistent health inequities. Analyses that examine SDOH individually may overlook important heterogeneity ...
The performance of latent class analysis for clustering multiple long-term conditions is robust to the impact of high prevalence conditions [0.03%]
潜类分析的性能具有鲁棒性,受高发疾病的影响较小,可有效用于多种长期慢病的聚类分析
Marzieh Shahmandi,Jonathan G Bunn,Chioma Elewa et al.
Marzieh Shahmandi et al.
Objective: Living with multiple long-term conditions (MLTC) is increasingly common, posing challenges for healthcare systems and individuals alike. Identifying clusters of co-occurring conditions has been proposed as key ...
Characterizing updated and living meta-analyses Part 1: A methodological scoping review on methods for conducting meta-analyses in updated and living systematic reviews [0.03%]
界定更新型和动态系统评价中的META分析的特点(第一部分):针对更新型及动态系统评价中META分析方法的系统评价性文献回顾研究
Menelaos Konstantinidis,Katerina-Maria Kontouli,Pavel Zhelnov et al.
Menelaos Konstantinidis et al.
Objective: Systematic reviews (SRs) provide the highest level of evidence for clinical and policy decision-making but quickly become outdated as new studies emerge. Updated systematic reviews (USRs) and living systematic ...
Andrea C Tricco,Lesley Uttley,David Moher et al.
Andrea C Tricco et al.