CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomized trials [0.03%]
CONSORT 声明、解释和详细说明-2022：随机试验中不良事件报告指南更新
Daniela R Junqueira,Liliane Zorzela,Susan Golder et al.
Daniela R Junqueira et al.
Randomized controlled trials remain the reference standard for healthcare research on effects of interventions, and the need to report both benefits and harms is essential. The Consolidated Standards of Reporting Trials (the main CONSORT) s...
The BIGG-REC database makes available all WHO/PAHO evidence informed recommendations [0.03%]
BIGG-REC数据库提供了所有世卫组织/泛美卫生组织的基于证据的建议
Martín Ragusa,Fernando Tortosa,Gabriel Rada et al.
Martín Ragusa et al.
Objectives: To build and maintain a living database of the Pan American Health Organization/World Health Organization (PAHO/WHO) recommendations developed using Grading of Recommendations Assessment, Development, and Eval...
Patient participation impacts outcome domain selection in core outcome sets for research: an updated systematic review [0.03%]
患者参与对核心结局集研究结果领域选择的影响：一项系统性综述的更新版
Susanna Dodd,Sarah L Gorst,Amber Young et al.
Susanna Dodd et al.
Objectives: The importance of including patients, carers, and the public in health research is well recognized, including the need to consider outcomes in health care research that reflect the priorities of patients. Core...
Increasing FDA-accelerated approval of single-arm trials in oncology (1992 to 2020) [0.03%]
1992至2020年肿瘤学单组试验加速获批趋势分析
Tatiane Bomfim Ribeiro,Charles L Bennett,Luis Enrique Colunga-Lozano et al.
Tatiane Bomfim Ribeiro et al.
Objectives: We aimed to map the characteristics of single-arm trials (SAT), report the Food and Drug Administration (FDA) transparency in presenting historical control, and to assess the confirmatory randomized controlled...
Presentation approaches for enhancing interpretability of patient-reported outcomes in meta-analyses: a systematic survey of Cochrane reviews [0.03%]
提高Meta分析中患者报告结果解释透明度的呈现方法：系统评价科克伦评价的研究
Linan Zeng,Liang Yao,Yuting Wang et al.
Linan Zeng et al.
Objectives: To systematically survey Cochrane reviews' approaches to calculating, presenting, and interpreting pooled estimates of patient-reported outcome measures (PROMs). ...
Bypassing phase 2 in cancer drug development erodes the risk/benefit balance in phase 3 trials [0.03%]
绕过癌症药物开发的二期临床试验会损害三期临床试验中的风险/获益平衡
Hannah Moyer,Merlin Bittlinger,Angela Nelson et al.
Hannah Moyer et al.
Objectives: Drug developers sometimes launch phase 3 (P3) trials without supporting evidence from phase 2 (P2) trials. We call this practice "P2 bypass." The aims of this study were to estimate the prevalence of P2 bypass...
Systematic review finds "spin" practices and poor reporting standards in studies on machine learning-based prediction models [0.03%]
系统评价发现基于机器学习的预测模型研究中存在“炒作”行为和较差的报告标准
Constanza L Andaur Navarro,Johanna A A Damen,Toshihiko Takada et al.
Constanza L Andaur Navarro et al.
Objectives: We evaluated the presence and frequency of spin practices and poor reporting standards in studies that developed and/or validated clinical prediction models using supervised machine learning techniques. ...
Development of an international glossary for clinical guidelines collaboration [0.03%]
临床实践指南协作国际词汇表的制订
Rachel E Christensen,Michael D Yi,Bianca Y Kang et al.
Rachel E Christensen et al.
Objectives: Clinical practice guidelines (CPGs) are often created through collaboration among organizations. The use of inconsistent terminology may cause poor communication and delays. This study aimed to develop a gloss...
Practical guide to the typical analysis of prognostic factors and biomarkers without the use of P-values [0.03%]
不用P值进行预后因素和生物标志物典型分析的实用指南
Yuxuan Jin,Michael W Kattan
Yuxuan Jin
Objectives: We have seen an increasing number of studies evaluating biomarkers and prognostic factors. Biomedical researchers like to draw conclusions based on P-values. However, P-values are often not needed for this typ...
Quality of surgical patient-reported outcome measure validation studies is often deficient: a systematic review [0.03%]
外科患者报告结果测量验证研究的质量常存在缺陷：系统综述
Mikko Uimonen,Ilari Kuitunen,Oskari Pakarinen et al.
Mikko Uimonen et al.
Objectives: To examine the methodological basis behind the conclusions of patient-reported outcome measure (PROM) validation studies. Study design and set...