Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure [0.03%]
功能性牛奶外泌体介导miR30d的心肌靶向递送治疗肥厚性心力衰竭
Lingjun Tong,Qiyue Wang,Yameng Zhang et al.
Lingjun Tong et al.
miR30d has been shown to reverse cardiac hypertrophy. However, effective delivery of miR30d to the heart is challenging. Here, we engineered milk-derived extracellular vesicles (mEVs) by surface functionalization with an ischemic myocardium...
Sequential activation of osteogenic microenvironment via composite peptide-modified microfluidic microspheres for promoting bone regeneration [0.03%]
通过复合肽修饰的微流控微球顺序激活骨形成微环境以促进骨再生
Liang Wu,Tao Xu,Sen Li et al.
Liang Wu et al.
The osteogenic microenvironment (OME) significantly influences bone repair; however, reproducing its dynamic activation and repair processes remains challenging. In this study, we designed injectable porous microspheres modified with compos...
Biomaterials and therapeutic strategies designed for tooth extraction socket healing [0.03%]
用于牙拔除创口愈合的生物材料及治疗策略
Yijia Yin,Fangyuan Shuai,Xian Liu et al.
Yijia Yin et al.
Tooth extraction is the most commonly performed oral surgical procedure, with a wide range of clinical indications. The oral cavity is a complex microenvironment, influenced by oral movements, salivary flow, and bacterial biofilms. These fa...
Corrigendum to "Electrically-driven drug delivery into deep cutaneous tissue by conductive microneedles for fungal infection eradication and protective immunity" [Biomaterials 314 (2025) 122908] [0.03%]
关于“导电微针电驱动药物输送至深层皮肤组织以消除真菌感染并提供保护性免疫”一文的勘误[Biomaterials 314 (2025) 122908]
Sumanta Ghosh,Mengjia Zheng,Jiahui He et al.
Sumanta Ghosh et al.
Published Erratum
Biomaterials. 2025 Apr:315:122973. DOI:10.1016/j.biomaterials.2024.122973 2025
Injectable and adhesive MgO2-potentiated hydrogel with sequential tumor synergistic therapy and osteogenesis for challenging postsurgical osteosarcoma treatment [0.03%]
一种可注射且具有粘性的载镁基纳米复合水凝胶及其在骨肉瘤手术后难题治疗中的应用
Wenjing Zhang,Long Li,Zishuo Wang et al.
Wenjing Zhang et al.
The clinical treatment of osteosarcoma faces great challenges of residual tumor cells leading to tumor recurrence and irregular bone defects difficult to repair after surgery removal of the primary tumor tissue. We developed an injectable a...
LIFU-unlocked endogenous H2S generation for enhancing atherosclerosis-specific gas-enzymatic therapy [0.03%]
利用LIFU解锁内源性H2S生成以增强动脉粥样硬化特异性气体酶治疗
Hongjin An,Xiaoling Qiu,Xiaoting Wang et al.
Hongjin An et al.
Atherosclerotic plaques, which are characterized by endothelial oxidative stress, lipid metabolism disorders and persistent inflammation, can induce serious cardiovascular diseases. However, the pharmacotherapies currently used to treat ath...
Histamine receptor agonism differentially induces immune and reparative healing responses in biomaterial-facilitated tissue repair [0.03%]
组胺受体激动剂在生物材料促进的组织修复中不同地诱导免疫和修复性愈合反应
Jordan R Yaron,Shubham Pallod,Nicole Grigaitis-Esman et al.
Jordan R Yaron et al.
Tissue repair is a highly regulated process involving immune, stromal, vascular, and parenchymal cell responses. Mediators of cellular responses at different phases of the healing process stimulate transitions through the continuum of repai...
Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse [0.03%]
钙磷酸盐纳米聚集体可调节牙周改建并减少正畸复发
Darnell L Cuylear,Moyu L Fu,Justin C Chau et al.
Darnell L Cuylear et al.
Orthodontic relapse is one of the most prevalent concerns of orthodontic therapy. Relapse results in patients' teeth reverting towards their pretreatment positions, which increases the susceptibility to functional problems, dental disease, ...
Corrigendum to "Poly(β-amino ester) polymer library with monomer variation for mRNA delivery" [Biomaterials 314 (2025) 122896] [0.03%]
关于“用于mRNA传递的单体可变聚(β-氨基酯)聚合物库”的勘误(生物材料，第314期(2025年)，122896)
Hong Lyun Kim,Gurusamy Saravanakumar,Seowon Lee et al.
Hong Lyun Kim et al.
Published Erratum
Biomaterials. 2025 Apr:315:122966. DOI:10.1016/j.biomaterials.2024.122966 2025
Remolding probiotics for effective treatment of type 2 diabetes via oral administration [0.03%]
口服给药有效治疗2型糖尿病的益生菌重塑
Haihua Ji,Yiqun Wan,Shengjie Li et al.
Haihua Ji et al.
Effective, user-friendly, lifestyle-compatible, and economic treatment for type 2 diabetes (T2D) is urgently needed due to its high incidence and health threats. Here, we remolded Lactococcus lactis through genetic engineering to persistent...