pH-responsive sparfloxacin/Fe3+ nanoparticles eradicate intratumoral bacteria and activate ferroptosis for enhanced antitumor immunotherapy in breast cancer [0.03%]
一种新型抗菌免疫治疗递送系统——制备兼有抗菌和激活铁死亡双重功能的左氧氟沙星/Fe³⁺纳米颗粒用于乳腺癌治疗
Zhiting Sun,Ming Xu,Lu Nie et al.
Zhiting Sun et al.
Tumor-resident microbiotas critically influence breast cancer progression and metastasis. To simultaneously eliminate intratumoral bacteria and induce tumor cell death, we developed pH-sensitive nanoparticles (PEPCA@SPA/Fe3+ NPs) by encapsu...
Sunlight triggered radical oxygen species redistribution in infected wound treatment [0.03%]
光敏引发的活性含氧物种重新分布促进感染伤口治疗
Bikun Zhou,Xingan Qiu,Pengzhen Bu et al.
Bikun Zhou et al.
Photodynamic therapy achieves antibacterial effects by generating reactive oxygen species (ROS), and is therefore used in the clinical treatment of infectious wounds. However, generated ROS also causes damage to surrounding normal tissues a...
Thermoplastic silk-plasticizer membranes for biodegradable artificial corneal endothelium [0.03%]
热塑性丝素塑化剂膜作为可生物降解人工角膜内皮的研究
Miaomiao Chi,Xiuyuan Luo,Bowei Yuan et al.
Miaomiao Chi et al.
Corneal endothelial dysfunction (CED) induces stromal edema through aqueous influx, disrupting collagen organization and causing corneal opacity, with chronic cases progressing to fibrosis. As a major cause of corneal blindness, CED current...
NIR-driven electron transfer for in situ gelation and enhanced hydrogen therapy [0.03%]
用于原位胶凝和增强氢疗法的近红外驱动电子转移
Ziyi Zhang,Ningjing Zhao,Wenting Li et al.
Ziyi Zhang et al.
Hydrogen therapy has shown significant promise in improving wound healing by mitigating oxidative stress and inflammation. However, its therapeutic efficacy is constrained by limited delivery methods and insufficient bioavailability of hydr...
Magnesium-based barrier membrane for guided bone regeneration: From bedside to bench and back again [0.03%]
镁基屏障膜引导骨再生：从床边到实验台再回归临床
Ping Li,Jiahao Chen,Franziska Schmidt et al.
Ping Li et al.
Magnesium (Mg)-based barrier membranes represent a promising advancement in guided bone regeneration (GBR) treatment, with significant potential due to their unique material properties. This comprehensive review is an in-depth exploration o...
Dual-loaded BMSCs-Metformin microgels promote cartilage repair through combined anti-inflammatory, antioxidant, and regenerative effects [0.03%]
双加载BMSCs-二甲双胍微凝胶通过联合抗炎、抗氧化和再生作用促进软骨修复
Danmei Li,Yixiang Wang,Guangxun Yuan et al.
Danmei Li et al.
The restricted self-healing capacity of articular cartilage, combined with the inflammatory response and oxidative stress that follow injury, makes articular cartilage restoration a challenging therapeutic problem. We engineered an injectab...
Co-localization of lymph node therapeutics enhances T cell activation and anti-tumor response [0.03%]
淋巴结治疗的共定位增强T细胞活化和抗肿瘤反应
Ruochen Shen,Senta M Kapnick,Camilla Edwards et al.
Ruochen Shen et al.
Lymph nodes (LNs) are essential tissues in generating and modulating effective immune responses. In this study, we investigated the intra-lymphatic delivery of immunotherapy cues encapsulated in degradable microparticles (MPs). We demonstra...
Corrigendum to "Local release of fibroblast growth factor 21 and cannabidiol promoting spinal cord nerve injury repair through activation of cannabinoid receptor 2" [Biomaterials. 325 (2026) 123609] [0.03%]
关于“局灶释放纤维细胞生长因子21和大麻二酚通过激活大麻素受体2促进脊髓神经损伤修复”一文的勘误[Biomaterials. 325 (2026) 123609]
Zhao Zhang,Zhengquan Wang,Zhihao Shen et al.
Zhao Zhang et al.
Published Erratum
Biomaterials. 2025 Oct 28:123801. DOI:10.1016/j.biomaterials.2025.123801 2025
Precision stem cell regeneration enabled by a collagen-targeting, fate-directing bi-functional peptide [0.03%]
一种靶向胶原蛋白、决定细胞命运的双功能肽实现高精度干细胞再生
Chun-Te Ho,Yu-Ching Liu,Chao-Jung Chen et al.
Chun-Te Ho et al.
Precise control over stem cell selection, delivery, and fate remains a key challenge in regenerative medicine. Here, we report a collagen-targeting, fate-directing bi-functional peptide (BiFP) that enhances stem cell therapy for osteoarthri...
pH-responsive neutrophil membrane camouflage Ga-Mn bimetallic nanodecoy triggers apoptosis-immunity-metastasis suppression for tumor therapy [0.03%]
一种用于肿瘤治疗的响应pH值的中性粒细胞膜伪装Ga-Mn双金属纳米诱饵引发凋亡-免疫-转移抑制疗法
Guangyu Ma,Silin Du,Xiang Li et al.
Guangyu Ma et al.
Mitochondria-mediated apoptosis and immunogenic cell death (ICD) are promising avenues in cancer therapy; however, they encounter challenges such as resistance to apoptosis and inadequate cytoplasmic sensing of mitochondrial DNA (mtDNA). Ad...