Comparative proteomic analysis of skin wound healing responses to biomaterial treatments identifies key pathways which govern differential regenerative outcomes [0.03%]
生物材料治疗皮肤伤口愈合的蛋白组学比较分析鉴定出决定不同再生结局的关键通路
Alejandra Suarez-Arnedo,Eleanor L P Caston,Yining Liu et al.
Alejandra Suarez-Arnedo et al.
The wound healing cascade is characterized by the steady progression of distinct stages. Though biomaterials are used clinically to enhance wound closure rate and quality of healed tissue, their mechanisms of action are less understood. Her...
Multiscale molecular engineering co-modulated dual-mode ratiometric probe for monitoring tumor-associated macrophage repolarization [0.03%]
多尺度分子工程协同调节双模式比值探针用于监测肿瘤相关巨噬细胞重极化
Xinyue Li,Ning Li,Zhiang Duan et al.
Xinyue Li et al.
Precise modulation of structure-function relationship of molecules is at the core of driving breakthroughs in biosensing technology through chemical strategy. Here, we present a near-infrared (NIR) ratiometric fluorescence/photoacoustic dua...
Non-covalent framework imparting "hot spring" dressing materials with high energy storage density and long-time heat release for wound treatment [0.03%]
一种非共价框架使温泉敷料材料具有高能量存储密度和长时间的热释放以用于伤口治疗
Lei Zhang,Zhongtao Wu,Lijia Jiang et al.
Lei Zhang et al.
Photon energy and low-grade heat are bio-friendly natural energies for creating mild heat stimulation that can promote the tissue repair process by enhancing angiogenesis and accelerating regeneration. Here, a type of azobenzene-containing ...
Precision targeted cancer-associated fibroblast nano-regulator enhanced chemo-immunotherapy for triple-negative breast cancer [0.03%]
用于三阴性乳腺癌的精准肿瘤相关成纤维细胞纳米调控增强型化疗免疫疗法
Peng Xian,Linghui Zou,Jiaxin Zhang et al.
Peng Xian et al.
Cancer-associated fibroblasts (CAFs), major components of the triple-negative breast cancer (TNBC) tumor microenvironment, affect tumor growth and limit the therapeutic efficacy of various clinical approaches by forming a dense stromal phys...
Corrigendum to 'Ultrathin chalcogenide nanosheets for photoacoustic imaging-guided synergistic photothermal/gas therapy' [Biomaterials 273 (2021) 120807] [0.03%]
“用于光声成像引导的超薄硫族元素纳米片的协同光热/气体治疗”的勘误表
Jingjing Wu,Gareth R Williams,Yu Zhu et al.
Jingjing Wu et al.
Published Erratum
Biomaterials. 2025 Sep 10:123688. DOI:10.1016/j.biomaterials.2025.123688 2025
Compositional "plainification" in biodegradable magnesium-rare earth alloys - Achieving well-balanced performance in an ultra-lean Mg-Pr alloy [0.03%]
生物可降解镁稀土合金的组分脱复杂化研究——超低含量Mg-Pr合金中的性能均衡策略
Ge Yang,Xiongke Hu,Xiaochuan Li et al.
Ge Yang et al.
Contrary to the traditional strengthening route by adding multiple & high-dosage alloying elements, we here explored extremely compositional and phase-constituent "simplification" in rare earth (RE) containing biodegradable magnesium alloys...
Investigating the functional contributions of phospholipids in selective organ targeting lipid nanoparticles [0.03%]
探究靶向器官脂质纳米颗粒中磷脂的功能作用
Erick D Guerrero,Amogh Vaidya,Julien Santelli et al.
Erick D Guerrero et al.
Modular lipid nanoparticles (LNPs) are a promising platform to deliver mRNA to various tissues and cells. Optimization of LNPs for hepatic and extrahepatic tissues often involves substitution of helper lipids or addition of novel lipids not...
Resolve and regulate: Alum nanoplatform coordinating STING availability and agonist delivery for enhanced anti-tumor immunotherapy [0.03%]
解决与调节：铝纳米平台协调STING的可用性和激动剂递送以增强抗肿瘤免疫治疗
Yu Sun,Hideki Nakanishi,Xiaonan Huang et al.
Yu Sun et al.
The stimulator of interferon genes (STING) pathway represents a promising target in cancer immunotherapy. However, the clinical translation of cyclic dinucleotide (CDN)-based STING agonists remains hindered by insufficient formation of func...
Ganghao Liang,Songyue Chen,Jun Chen
Ganghao Liang
Wearable bioelectronics have transformed modern biomedical applications by enabling seamless integration with biological tissues, providing continuous, comprehensive, and personalized healthcare. Skin cancer, particularly melanoma, poses a ...
Senescence-regulating agents remodel mesenchymal stem cell-schwann cell circuitry for diabetic bone regeneration [0.03%]
衰老调节剂重塑间充质干细胞-施万细胞回路用于糖尿病骨再生
An Lao,Yiting Sun,Weiqi Li et al.
An Lao et al.
Bone healing requires Schwann cells (SCs) paracrine factors for mesenchymal stem cell function. Diabetes mellitus (DM) patients are susceptible to developing SCs dysfunction and impairing bone healing. Rare research considered reconstructin...