Interrogating functional connectivity of in vitro neural glia tissue model modulated through integrative control of matrix stiffness and a neurotrophic factor [0.03%]
通过整合控制基质刚度和神经营养因子的体内神经胶质组织模型的功能连接研究
Sehong Kang,Eun Mi Kim,Eric Burgeson et al.
Sehong Kang et al.
Brain function emerges from intricate cellular communication within neural networks. Both In silico neuronal models and primary neuron cells have revealed that the branching architecture of individual neurons determines the bioelectrical si...
Stimulus-responsive AIE nanoassembly for NIR-II imaging-guided cascade photothermal/photodynamic/gas synergistic thrombolysis and vascular healing [0.03%]
刺激响应型聚集诱导发光纳米复合材料用于近红外二区成像引导的协同光热/光动力/气体溶血和血管修复
Dan Zhou,Jialin Tong,Liping Zhang et al.
Dan Zhou et al.
Thrombosis remains a major contributor to cardiovascular diseases globally, yet current therapeutic strategies are hindered by narrow therapeutic windows, suboptimal thrombolytic efficacy, and inflammation-driven recurrence. Herein, we repo...
Corrigendum to "PEGylated immunoliposome-loaded endoglin single-chain antibody enhances anti-tumor capacity of porcine α1,3GT gene" [Biomaterials 217 (2019) 119231] [0.03%]
“聚乙二醇化免疫脂质体加载内皮素单链抗体增强猪α1，3gt基因的抗肿瘤能力”[生物材料217（2019）119231]的勘误表
Yingying Huang,Yong Huang,Jian He et al.
Yingying Huang et al.
Published Erratum
Biomaterials. 2025 Sep 15:123687. DOI:10.1016/j.biomaterials.2025.123687 2025
A degradable scaffold enabling shape matching and bone-mimetic biomechanics via in-situ forming for promoting bone defect repair [0.03%]
一种可降解的匹配缺陷形状并具有仿生力学性能的骨缺损修复植入体
Zijian Bao,Binggang Chen,Ran Yang et al.
Zijian Bao et al.
Segmental bone defect repair remains a persistent challenge in clinical orthopedics. Implanting degradable bioactive scaffold to induce bone regeneration represents a promising therapeutic strategy. However, existing scaffold materials stru...
Chemotaxis-guided nanoplatform for non-alcoholic steatohepatitis therapy via macrophage reprogramming, hepatoprotection and gut microbiome modulation [0.03%]
趋化因子引导的纳米平台通过巨噬细胞重编程、肝保护和肠道菌群调节治疗非酒精性脂肪性肝炎
Xier Pan,Xinyi Chen,Ying Ma et al.
Xier Pan et al.
Non-alcoholic steatohepatitis (NASH), characterized by hepatic steatosis, inflammation, and varying degrees of fibrosis, has become a growing global health burden. Obeticholic acid (OCA, a farnesoid X receptor agonist) has shown limited eff...
Nanoengineered T cell membrane-coated nanodecoys blocking LAG-3/FGL1 to enhance cancer immunotherapy [0.03%]
纳米工程T细胞膜涂层纳痘剂阻断LAG-3/FGL1以增强癌症免疫治疗
Xiaoxia Xu,Beibei Zhang,Ge Chen et al.
Xiaoxia Xu et al.
Immune checkpoint blockade resistance, driven by alternative immune checkpoint upregulation and inefficient T cell-mediated immune stimulation, remains a major challenge in cancer immunotherapy. Here, we present a nanoengineered T cell memb...
DETOX: An innovative dendritic nanosystem for the delivery of BoNT/A LC domain to ischemic neurons [0.03%]
一种创新树突状纳米系统 用于向缺血神经元递送肉毒杆菌素A轻链域名
Marília Torrado,Clara Sinthon,Duarte Silva et al.
Marília Torrado et al.
Ischemic stroke is a leading cause of mortality and morbidity worldwide. Nevertheless, current treatments are very ineffective as they only restore the blood flow, lacking neuroprotective properties. Excitotoxicity, primarily mediated by th...
Self-assembled hADSCs/hNSCs spheroids combined with 3D printed M-shaped GelMA/Pu Scaffolds: Creating histologically biomimetic engineered cartilage that meets the characteristics of alar cartilage [0.03%]
自组装的hADSCs / hNSCs球体与3D打印的M形凝胶明胶（GelMA）/聚氨酯（Pu）支架结合：创建类软骨组织工程移植物以满足翼状软骨特性
Guanhuier Wang,Weibo Lin,Wenqiang Yan et al.
Guanhuier Wang et al.
Background: Traditional cartilage grafts for nasal alar retraction repair often lack sufficient elasticity and histocompatibility, leading to suboptimal clinical outcomes. To address this challenge, we developed a biomime...
Dynamic ROS-responsive hyperbranched polymer-based neuroprotective drug delivery system for pathogenesis-adaptive sequential therapy of cerebral ischemic stroke [0.03%]
一种针对脑缺血病理变化的自适应序贯治疗的动态ROS响应型神经保护药物输送系统
Xutao Ma,Xue Zhang,Yanan Wang et al.
Xutao Ma et al.
The limited delivery efficiency of most therapeutic drugs is a major challenge for effective treatment of ischemic stroke. Herein, we synthesized a ROS-cleavable thioacetal (TA)-linked precursor with multiple reactivities from scratch using...
EMERGE patch, a novel electrogenic engineered material to enhance healing of severe corneal wounds [0.03%]
一种新型电活性工程材料EMERGE补丁可促进严重角膜伤口愈合
Li Ma,Brian Reid,Lance Baird et al.
Li Ma et al.
Severe corneal wounds with stromal damage, especially those inflicted in battlefield and terrorist attacks, remain a significant clinical challenge. Naturally occurring wound electric fields have been demonstrated to have powerful effects o...