Cochlear histopathology in human genetic hearing loss: State of the science and future prospects [0.03%]
人遗传性听力损失的耳蜗组织病理学：现状与未来前景
Krishna Bommakanti,Janani S Iyer,Konstantina M Stankovic
Krishna Bommakanti
Sensorineural hearing loss (SNHL) is an extraordinarily common disability, affecting 466 million people across the globe. Half of these incidents are attributed to genetic mutations that disrupt the structure and function of the cochlea. Th...
Afferent-efferent connectivity between auditory brainstem and cortex accounts for poorer speech-in-noise comprehension in older adults [0.03%]
听觉脑干和皮层的传入和传出连接性解释了老年人较差的噪音下言语理解能力
Gavin M Bidelman,Caitlin N Price,Dawei Shen et al.
Gavin M Bidelman et al.
Speech-in-noise (SIN) comprehension deficits in older adults have been linked to changes in both subcortical and cortical auditory evoked responses. However, older adults' difficulty understanding SIN may also be related to an imbalance in ...
Deborah A Hall,Christopher J Plack
Deborah A Hall
A simple algorithm for objective threshold determination of auditory brainstem responses [0.03%]
听性脑干反应客观阈值检测的简单算法
Kirupa Suthakar,M Charles Liberman
Kirupa Suthakar
The auditory brainstem response (ABR) is a sound-evoked neural response commonly used to assess auditory function in humans and laboratory animals. ABR thresholds are typically chosen by visual inspection, leaving the procedure susceptible ...
Comparative Study
Hearing research. 2019 Sep 15:381:107782. DOI:10.1016/j.heares.2019.107782 2019
Repeated temporary threshold shift and changes in cochlear and neural function [0.03%]
听觉阈值的暂时性改变及耳蜗和神经的功能变化
D S Morgan,A A Arteaga,N A Bosworth et al.
D S Morgan et al.
A robust temporary threshold shift (TTS) can create significant primary damage to the auditory synapse, termed cochlear synaptopathy (CS). The common model applied to examination of this pathology is a single noise exposure or extended dura...
NLRP3 inflammasome activation in human vestibular schwannoma: Implications for tumor-induced hearing loss [0.03%]
人类前庭神经鞘瘤中NLRP3炎症小体的激活：对肿瘤诱导性听力损失的意义
Jessica E Sagers,Mehmet I Sahin,InSeok Moon et al.
Jessica E Sagers et al.
Vestibular schwannoma (VS) is the fourth most common intracranial tumor, arising from neoplastic Schwann cells of the vestibular nerve and often causing debilitating sensorineural hearing loss (SNHL) and tinnitus. Previous research suggests...
Meta-Analysis
Hearing research. 2019 Sep 15:381:107770. DOI:10.1016/j.heares.2019.07.007 2019
Visual input shapes the auditory frequency responses in the inferior colliculus of mouse [0.03%]
视觉输入影响小鼠下丘的听觉频率反应
Liang Cheng,Xin-Yuan Fei,Yi-Li Qu
Liang Cheng
The integration of visual and auditory information is important for humans or animals to build an accurate and coherent perception of the external world. Although some evidence has shown some principles of the audiovisual integration, littl...
Effects of developmental noise exposure on inhibitory cell densities and perineuronal nets in A1 and AAF of mice [0.03%]
噪声暴露对小鼠听皮层和听觉野外抑制性神经元密度及周围神经网状结构的影响
Sarah M Reinhard,Maximiliano Abundez-Toledo,Katherine Espinoza et al.
Sarah M Reinhard et al.
Within the auditory cortex, there are two primary-like regions considered to be 'core' cortical fields, the primary auditory cortex (A1) and the anterior auditory field (AAF). Both fields have sharp frequency tuning, tonotopic organization,...
Nelson's notch in the rate-level functions of auditory-nerve fibers might be caused by PIEZO2-mediated reverse-polarity currents in hair cells [0.03%]
内耳皮层Piezo2介导的反极化电流可能是形成神经纤维速率水平函数中纳尔逊缺口的原因
Peter Heil,Adam J Peterson
Peter Heil
Half a century ago, Nelson Kiang and colleagues observed that some spike rate versus stimulus level functions of auditory-nerve-fiber responses to tones are nonmonotonic, exhibiting a sharp notch ("Nelson's notch") at high stimulus levels. ...
The in-air auditory thresholds of the eurasian otter (Lutra lutra, L. 1758) as determined by auditory brainstem responses [0.03%]
听脑干反应确定欧亚水獭(Lutra lutra, L. 1758)空中听阈值研究
Mathias Benjamin Voigt,Christian Hackenbroich,Hans-Heinrich Krüger et al.
Mathias Benjamin Voigt et al.
As of yet there is no literature record of the hearing range of the Eurasian otter (Lutra lutra, L. 1758), a key species for natural conservation efforts in Europe. We recorded in-air pure tone hearing thresholds of anaesthetized otters usi...