C57BL/6-derived mice and the Cdh23ahl allele - Background matters [0.03%]
背景因素会影响Cdh23ahl突变体小鼠听力下降模型的效果
Sherylanne Newton,Carlos Aguilar,Michael R Bowl
Sherylanne Newton
C57BL/6-derived mice are the most utilised mice in biomedical research, and yet actually there is no such thing as a generic C57BL/6 mouse. Instead, there are more than 150 C57BL/6-derived sub-strains recognised by the Mouse Genome Informat...
Pascal Barone,Andrej Kral
Pascal Barone
Assessing behavioral and neural correlates of change detection in spatialized acoustic scenes [0.03%]
基于空间声场的听觉变化感知的行为学和神经机制研究
Katarina C Poole,Drew Cappotto,Vincent Martin et al.
Katarina C Poole et al.
The ability to detect changes in complex auditory scenes is crucial for human survival, yet the neural mechanisms underlying this process remain elusive. This study investigates how the presence and location of sound sources impacts active ...
Cochlear representation of wideband biosonar sounds and the emergence of neural oscillations [0.03%]
宽频生物声纳信号的耳蜗表征及其神经振荡现象的产生
James A Simmons,Darlene R Ketten,Andrea Megela Simmons
James A Simmons
Echolocating big brown bats and bottlenose dolphins broadcast wideband ultrasonic echolocation calls in the baseband to sense their surroundings. Even though these species inhabit different media and emit echolocation calls with different s...
Axon terminal distribution in layer 1 of the mouse auditory cortex: differential projections from the dorsal and medial subdivisions of the medial geniculate body and the marginal zone of the posterior thalamic nuclei [0.03%]
鼠听皮层第1层轴突末端的投射：上丘脑后核边缘区和腹侧、中侧膝状体亚核至听皮层第1层轴突末端的差异性分布模式研究
Meng Sun,Makoto Takemoto,Ryohei Tomioka et al.
Meng Sun et al.
Layer 1 (L1) of the neocortex integrates bottom-up and top-down signals. Inputs to L1, however, remain incompletely characterized. L1 of the auditory cortex (ACX) receives ascending inputs from the medial geniculate body (MGB) subdivisions ...
Clonidine mitigates noise-induced hearing loss by regulating TRPC6-mediated calcium influx in cochlear hair cells [0.03%]
克伦欣定通过调节耳蜗毛细胞中TRPC6介导的钙离子流入来缓解噪声引起的听力损失
Wenji Zhai,Xiaojing Kuang,Jie Wu et al.
Wenji Zhai et al.
Noise-induced hearing loss (NIHL) is a common auditory disorder driven by calcium overload, oxidative stress, and apoptosis in cochlear sensory hair cells. The transient receptor potential canonical 6 (TRPC6), a nonselective cation channel ...
Sustained Wnt signaling in the mouse inner ear after morphogenesis: In hair cells, supporting cells, and spiral ganglion neurons [0.03%]
小鼠内耳在形态建立后的持续Wnt信号传导：毛细胞、支持细胞和螺旋神经节神经元中的信号转导
Teppei Noda,Takahiro Wakizono,Takahiro Manabe et al.
Teppei Noda et al.
The regenerative capacity of inner ear hair cells in mammals varies between the cochlea and the vestibular system. Hair cells in the cochlea lack regenerative ability, whereas those in the vestibular system exhibit limited regenerative pote...
ABRpresto: An algorithm for automatic thresholding of the Auditory Brainstem Response using resampled cross-correlation across subaverages [0.03%]
基于子平均交叉互相关的听觉脑干反应自动阈值算法ABRpresto
Luke A Shaheen,Brad N Buran,Kirupa Suthakar et al.
Luke A Shaheen et al.
The Auditory Brainstem Response (ABR) is an essential diagnostic indicator of overall health of cochlea, auditory brainstem and midbrain, used extensively in both basic research and clinical studies. A key quantification of the ABR is thres...
The cortilymph wave: Its relation to the traveling wave, auditory-nerve responses, and low-frequency downward glides [0.03%]
耳蜗淋巴波：与行波、听神经反应及低频下行滑动的关系
John J Guinan Jr
John J Guinan Jr
In the cochlear base, recent data show that amplification of the traveling wave does not come from outer-hair-cell (OHC) forces acting on the basilar membrane (BM). Instead, traveling wave amplification is hypothesized to come from OHCs pro...
Coupling-induced tunability of characteristic frequency, bandwidth and gain of artificial hair cells [0.03%]
耦合诱导的人工毛细胞本征频率、带宽和增益的可调性
Kalpan Ved,Hermann Folke Johann Rolf,Tzvetan Ivanov et al.
Kalpan Ved et al.
Drawing inspiration from nature, we develop bio-inspired acoustic sensors with integrated signal processing capabilities to (i) close the performance gap between the human hearing and machine hearing and (ii) test models on biological heari...