Sonia Tabibi,Andrea Kegel,Wai Kong Lai et al.
Sonia Tabibi et al.
A bio-inspired coding (BIC) strategy was implemented in this study with the goal of better representation of spectral and temporal information. The auditory nerve fibers' (ANFs) characteristics such as refractory recovery, facilitation and ...
Comparative Study
Hearing research. 2020 Mar 15:388:107885. DOI:10.1016/j.heares.2020.107885 2020
Post-natal development of the envelope following response to amplitude modulated sounds in the bat Phyllostomus discolor [0.03%]
短尾蝠（Phyllostomus discolor）对调制声音的包络跟随反应的产后发育
Stephen Gareth Hörpel,Uwe Firzlaff
Stephen Gareth Hörpel
Bats use a large repertoire of calls for social communication, which are often characterized by temporal amplitude and frequency modulations. As bats are considered to be among the few mammalian species capable of vocal learning, the percep...
Comparative Study
Hearing research. 2020 Mar 15:388:107904. DOI:10.1016/j.heares.2020.107904 2020
The expression of copper transporters associated with the ototoxicity induced by platinum-based chemotherapeutic agents [0.03%]
与铂类化疗药诱发的耳毒性相关的铜转运蛋白的表达调控
Maria Perde-Schrepler,Eva Fischer-Fodor,Piroska Virag et al.
Maria Perde-Schrepler et al.
Background: Antitumor agents based on platinum have gained a well-established place in the treatment of several forms of cancer. Their efficiency is hampered by serious toxic effects against healthy tissues as well. Ototo...
Comparative Study
Hearing research. 2020 Mar 15:388:107893. DOI:10.1016/j.heares.2020.107893 2020
Molecular basis and restoration of function deficiencies of Kv7.4 variants associated with inherited hearing loss [0.03%]
与遗传性听力损失相关的Kv7.4变异体的功能缺陷的分子机制及功能恢复研究
Xin Xia,Qiansen Zhang,Yanyan Jia et al.
Xin Xia et al.
Deafness non-syndromic autosomal dominant 2 (DFNA2) is characterized by symmetric, predominantly high-frequency sensorineural hearing loss that is progressive across all frequencies. The disease is associated with variants of a potassium vo...
HyunJung An,Ryszard Auksztulewicz,HiJee Kang et al.
HyunJung An et al.
Predictive coding is an influential theory of neural processing underlying perceptual inference. However, it is unknown to what extent prediction violations of different sensory features are mediated in different regions in auditory cortex,...
Dissociable neural effects of temporal expectations due to passage of time and contextual probability [0.03%]
时间流逝和情境概率分别引起的时空预期的神经机制的区别效应
Ana Todorovic,Ryszard Auksztulewicz
Ana Todorovic
The human brain is equipped with complex mechanisms to track the changing probability of events in time. While the passage of time itself usually leads to a mounting expectation, context can provide additional information about when events ...
Neural processes of auditory perception in Heschl's gyrus for upcoming acoustic stimuli in humans [0.03%]
海马回对即将到来的听觉刺激的人类神经过程
Minjing Hu,Di Wang,Xuanxiu Ji et al.
Minjing Hu et al.
In the natural environment, attended sounds tend to be perceived much better than unattended sounds. However, the physiological mechanism of how our neural systems direct the state of perceptual attention to prepare for the detection of upc...
Generation of a ChATCre mouse line without the early onset hearing loss typical of the C57BL/6J strain [0.03%]
无C57BL/6J小鼠品系早期听力损失的ChATCre小鼠系的产生
Nichole L Beebe,Colleen S Sowick,Inga Kristaponyte et al.
Nichole L Beebe et al.
The development of knockin mice with Cre recombinase expressed under the control of the promoter for choline acetyltransferase (ChAT) has allowed experimental manipulation of cholinergic circuits. However, currently available ChATCre mouse ...
Age-related changes in the number of cresyl-violet-stained, parvalbumin and NMDAR 2B expressing neurons in the human spiral ganglion [0.03%]
人耳蜗神经节双苯胺紫染色、_parvalbumin_和_NMDAR_2B阳性神经元数量的年龄相关变化规律研究
Charanjeet Kaur,Shubhi Saini,Indra Pal et al.
Charanjeet Kaur et al.
Animal-studies associate age-related hearing loss (presbycusis) with decreasing number of spiral ganglion neurons (SGNs) in Rosenthal's canal (RC) of cochlea. The excitatory neurotransmitter for SGNs is glutamate (through its receptor NMDAR...
Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B [0.03%]
携带ADGB的AAV9-php.b.utricular注射有效转导小鼠内耳毛细胞
John Lee,Carl Nist-Lund,Paola Solanes et al.
John Lee et al.
Viral delivery of exogenous coding sequences into the inner ear has the potential for therapeutic benefit for patients suffering genetic or acquired hearing loss. To devise improved strategies for viral delivery, we investigated two injecti...