Translational and interdisciplinary insights into presbyacusis: A multidimensional disease [0.03%]
老龄化听力损失的跨学科和交叉学科见解：一种多维疾病
Mark A Eckert,Kelly C Harris,Hainan Lang et al.
Mark A Eckert et al.
There are multiple etiologies and phenotypes of age-related hearing loss or presbyacusis. In this review we summarize findings from animal and human studies of presbyacusis, including those that provide the theoretical framework for distinc...
Expression pattern of brain-derived neurotrophic factor and its associated receptors: Implications for exogenous neurotrophin application [0.03%]
脑源性神经营养因子及其受体的表达模式：外源性神经营养素应用的意义
Jennifer Schulze,Hinrich Staecker,Dirk Wedekind et al.
Jennifer Schulze et al.
The application of neurotrophins such as brain-derived neurotrophic factor (BDNF) is a promising pharmacological approach in cochlear implant research. Several in vitro and in vivo studies demonstrated that treatment with neurotrophins supp...
Factors influencing classification of frequency following responses to speech and music stimuli [0.03%]
影响语音和音乐刺激诱发频率跟随反应分类的因素分析
Steven Losorelli,Blair Kaneshiro,Gabriella A Musacchia et al.
Steven Losorelli et al.
Successful mapping of meaningful labels to sound input requires accurate representation of that sound's acoustic variances in time and spectrum. For some individuals, such as children or those with hearing loss, having an objective measure ...
Is cochlear synapse loss an origin of low-frequency hearing loss associated with endolymphatic hydrops? [0.03%]
膜迷路积水相关低频听力下降的毛细胞突触损失病因学研究
Carla V Valenzuela,Choongheon Lee,Abby Mispagel et al.
Carla V Valenzuela et al.
There is a strong association between endolymphatic hydrops and low-frequency hearing loss, but the origin of the hearing loss remains unknown. A reduction in the number of cochlear afferent synapses between inner hair cells and auditory ne...
Frequency selectivity of tonal language native speakers probed by suppression tuning curves of spontaneous otoacoustic emissions [0.03%]
语频谱图中 tonal 语言母语者的频率特异性研究
Sina Engler,Emile de Kleine,Paul Avan et al.
Sina Engler et al.
Native acquisition of a tonal language (TL) is related to enhanced abilities of pitch perception and production, compared to non-tonal language (NTL) native speakers. Moreover, differences in brain responses to both linguistically relevant ...
Cochlear microphonic latency predicts outer hair cell function in animal models and clinical populations [0.03%]
耳蜗微音器潜伏期预测动物模型和临床人群的外毛细胞功能
Christofer Bester,Stefan Weder,Aaron Collins et al.
Christofer Bester et al.
As recently reported, electrocochleography recorded in cochlear implant recipients showed reduced amplitude and shorter latency in patients with more severe high-frequency hearing loss compared with those with some residual hearing. As the ...
Translational implications of the interactions between hormones and age-related hearing loss [0.03%]
激素与年龄相关性听力损失之间相互作用的临床意义
R D Frisina,P Bazard,M Bauer et al.
R D Frisina et al.
Provocative research has revealed both positive and negative effects of hormones on hearing as we age; with in some cases, mis-regulation of hormonal levels in instances of medical comorbidities linked to aging, lying at the heart of the pr...
Short and long-term adaptation in the auditory nerve stimulated with high-rate electrical pulse trains are better described by a power law [0.03%]
高频率电脉冲刺激听神经的短期和长期适应现象更好地用幂律描述
M J van Gendt,M Siebrecht,J J Briaire et al.
M J van Gendt et al.
Despite the introduction of many new sound-coding strategies speech perception outcomes in cochlear implant listeners have leveled off. Computer models may help speed up the evaluation of new sound-coding strategies, but most existing model...
Perception and prediction of loudness in sound coding strategies using simultaneous electric stimulation [0.03%]
使用同时电刺激的声音编码策略中响度的感知和预测
Florian Langner,Colette M McKay,Andreas Büchner et al.
Florian Langner et al.
Cochlear Implant (CI) sound coding strategies based on simultaneous stimulation lead to an increased loudness percept when compared to sequential stimulation using the same current levels. This is due to loudness summation as a result of ch...
Changes in audiometric threshold and frequency selectivity correlate with cochlear histopathology in macaque monkeys with permanent noise-induced hearing loss [0.03%]
恒河猴永久性噪声性听力损失的听阈和频率选择性的变化与耳蜗的组织病理学改变相关分析
Jane A Burton,Chase A Mackey,Kaitlyn S MacDonald et al.
Jane A Burton et al.
Exposure to loud noise causes damage to the inner ear, including but not limited to outer and inner hair cells (OHCs and IHCs) and IHC ribbon synapses. This cochlear damage impairs auditory processing and increases audiometric thresholds (n...