Postnatal development of subfields in the core region of the mouse auditory cortex [0.03%]
小鼠听皮层核心区亚区的产后发育时间表
Feifan Chen,Makoto Takemoto,Masataka Nishimura et al.
Feifan Chen et al.
The core region of the rodent auditory cortex has two subfields: the primary auditory area (A1) and the anterior auditory field (AAF). Although the postnatal development of A1 has been studied in several mammalian species, few studies have ...
BDNF-mediated preservation of spiral ganglion cell peripheral processes and axons in comparison to that of their cell bodies [0.03%]
脑源性神经营养因子介导的螺旋神经节细胞周围过程和轴突的维持与胞体的比较研究
Henk A Vink,Huib Versnel,Steven Kroon et al.
Henk A Vink et al.
Treatment with neurotrophins prevents degeneration of spiral ganglion cells (SGCs) after severe hair cell loss. In a previous study we demonstrated a long-lasting effect with brain-derived neurotrophic factor (BDNF) after cessation of treat...
Breaking the sound barrier: Towards next-generation AAV vectors for gene therapy of hearing disorders [0.03%]
突破声音屏障:面向基因治疗听力障碍的下一代AAV载体研究趋势
Julia Fakhiri,Lukas D Landegger,Dirk Grimm
Julia Fakhiri
Owing to the advances in transgenic animal technology and the advent of the next-generation sequencing era, over 120 genes causing hereditary hearing loss have been identified by now. In parallel, the field of human gene therapy continues t...
Effects of age on psychophysical measures of auditory temporal processing and speech reception at low and high levels [0.03%]
年龄对听觉时间处理和低强度及高强度语音接收的心理物理测量的影响
Samuele Carcagno,Christopher J Plack
Samuele Carcagno
Age-related cochlear synaptopathy (CS) has been shown to occur in rodents with minimal noise exposure, and has been hypothesized to play a crucial role in age-related hearing declines in humans. It is not known to what extent age-related CS...
Effect of exceeding compliance voltage on speech perception in cochlear implants [0.03%]
Cochlear植入超过符合电压对言语感知的影响
Aniket A Saoji,Weston J Adkins,Amy P Olund et al.
Aniket A Saoji et al.
Objectives: In cochlear implants, the maximum current I (Amperes) that can be delivered on a cochlear implant electrode is determined by V = I * R, where V = compliance voltage (Volts) and R = electrode impedance (Ohms). ...
Josef Syka,Barbara Canlon
Josef Syka
Immunohistochemical location of Na+, K+-ATPase α1 subunit in the human inner ear [0.03%]
人内耳Na+,K+-ATP酶α1亚单位的免疫组织化学定位
Ryan Stephenson,Astkhik Mangasarian,Gail Ishiyama et al.
Ryan Stephenson et al.
Na+, K+-ATPase (Na,K-ATPase) is an ubiquitous enzyme in the inner ear and a key factor in the maintenance of the osmotic gradient of the endolymph. This study uses Na,K-ATPase α1 subunit immunoreactivity (IR) to identify cellular structure...
Cortical processing of location and frequency changes of sounds in normal hearing listeners [0.03%]
正常听觉者对声音定位和频率变化的皮层处理
Fawen Zhang,Kelli McGuire,Gabrielle Firestone et al.
Fawen Zhang et al.
Sounds we hear in our daily life contain changes in the acoustic features (e.g., frequency, intensity, and duration or "what" information) and/or changes in location ("where" information). The purpose of this study was to examine the cortic...
Marlin Johansson,Åke Olofsson,Erik Berninger
Marlin Johansson
Our knowledge of which physiological mechanisms shape transient evoked otoacoustic emissions (TEOAEs) is incomplete, although thousands of TEOAEs are recorded each day as part of universal newborn hearing-screening (UNHS). TEOAE heritabilit...
Liangjie Chen,Yu Ding,Qingxin Meng et al.
Liangjie Chen et al.
In a reverberant environment, humans with normal hearing can perceptually fuse the soundwave from a source with its reflections off nearby surfaces into a single auditory image, whose location appears to be around the source. This phenomeno...