The reduced auditory evoked potential component N1 after repeated stimulation: Refractoriness hypothesis vs. habituation account [0.03%]
听觉诱发位相N1重复刺激后的减弱：适应作用假说和不应期假说的对比研究
Timm Rosburg,Ralph Mager
Timm Rosburg
Similar to other event-related potential (ERP) components, the amplitude of the auditory evoked N1 depends on the interstimulus interval (ISI). At ISIs > 0.4 s, the amplitude of the N1 increases with longer ISIs, until it saturates at ISIs ...
Geoffrey A Manley
Geoffrey A Manley
The erroneous idea that mammalian three-ossicle middle ears are superior to single-ossicle ones has influenced thinking about prostheses. Evolutionary facts and measurements indicate that single-ossicle ears are equivalent and more flexible...
Impact of the sensory environment on balance in children with bilateral cochleovestibular loss [0.03%]
感觉环境对双侧耳蜗前庭损伤儿童平衡影响的研究
Nikolaus E Wolter,Karen A Gordon,Jennifer Campos et al.
Nikolaus E Wolter et al.
Background: The aim of the present study was to determine the role of auditory and visual sensory input on balance in children with bilateral cochlevestibular loss. The prevalence of vestibular impairment, and specificall...
Randomized Controlled Trial
Hearing research. 2021 Feb:400:108134. DOI:10.1016/j.heares.2020.108134 2021
The second harmonic neurons in auditory midbrain of Hipposideros pratti are more tolerant to background white noise [0.03%]
白纹异胸蝠听中脑第二谐波神经元具有更强的背景噪声容忍度
Zhongdan Cui,Guimin Zhang,Dandan Zhou et al.
Zhongdan Cui et al.
Although acoustic communication is inevitably influenced by noise, behaviorally relevant sounds are perceived reliably. The noise-tolerant and -invariant responses of auditory neurons are thought to be the underlying mechanism. So, it is re...
Melodic interval perception with acoustic and electric hearing in bimodal and single-sided deaf cochlear implant listeners [0.03%]
听觉模式和单侧植入人工耳蜗患者对旋律音程的感知能力
Emily R Spitzer,John J Galvin rd,David R Friedmann et al.
Emily R Spitzer et al.
Two notes sounded sequentially elicit melodic intervals and contours that form the basis of melody. Many previous studies have characterized pitch perception in cochlear implant (CI) users to be poor which may be due to the limited spectro-...
Novel 3D-printed hollow microneedles facilitate safe, reliable, and informative sampling of perilymph from guinea pigs [0.03%]
新型3D打印中空微针可安全、可靠地采集 Guinea Pig 的内淋巴以获得信息式样本
Betsy Szeto,Aykut Aksit,Chris Valentini et al.
Betsy Szeto et al.
Background: Inner ear diagnostics is limited by the inability to atraumatically obtain samples of inner ear fluid. The round window membrane (RWM) is an attractive portal for accessing perilymph samples as it has been sho...
Cochlear spiral ganglion neuron degeneration following cyclodextrin-induced hearing loss [0.03%]
环糊精诱导的听力损失后的耳蜗螺旋神经元退变
Dalian Ding,Haiyan Jiang,Richard Salvi
Dalian Ding
Because cyclodextrins are capable of removing cholesterol from cell membranes, there is growing interest in using these compounds to treat diseases linked to aberrant cholesterol metabolism. One compound, 2-hydroxypropyl-beta-cyclodextrin (...
Tricellular adherens junctions provide a cell surface delivery platform for connexin 26/30 oligomers in the cochlea [0.03%]
三细胞粘附连接复合体是耳蜗中缝隙连接蛋白Connexin26/30递送的平台
Jean Defourny,Marc Thiry
Jean Defourny
In the cochlea, connexins 26 (Cx26) and 30 (Cx30) largely co-assemble into heteromeric gap junctions, which connect adjacent non-sensory epithelial cells. These channels are believed to ensure the rapid removal of K+ away from the base of s...
Structural stiffening in the human middle ear due to static pressure: Finite-element analysis of combined static and dynamic middle-ear behavior [0.03%]
静水压作用下人耳中耳结构加固的有限元分析及静态和动态中耳行为的组合研究
Pieter G G Muyshondt,Joris J J Dirckx
Pieter G G Muyshondt
The vibration response of the middle ear (ME) to sound changes when static pressure gradients are applied across the tympanic membrane (TM). To date, it has not been well understood which mechanisms lead to these changes in ME vibration res...
GJB2 mutation spectrum in the Taiwanese population and genotype-phenotype comparisons in patients with hearing loss carrying GJB2 c.109G>A and c.235delC mutations [0.03%]
台湾人群连接蛋白2基因突变分布及连接蛋白2基因c.109G>A和c.235delC突变患者的听力损失表型分析
Yi-Feng Lin,Hung-Ching Lin,Chia-Ling Tsai et al.
Yi-Feng Lin et al.
Hearing loss, the most common sensory abnormality, is caused by the death of or damage to inner ear hair cells. Genetic mutations are the main cause of hearing loss. We used nex-generation sequencing data released by the Taiwan Biobank to i...