CACHD1-deficient mice exhibit hearing and balance deficits associated with a disruption of calcium homeostasis in the inner ear [0.03%]
缺少CACHD1的小鼠出现与内耳钙稳态紊乱相关的听力和平衡障碍
Cong Tian,Kenneth R Johnson,Jaclynn M Lett et al.
Cong Tian et al.
CACHD1 recently was shown to be an α2δ-like subunit that can modulate the activity of some types of voltage-gated calcium channels, including the low-voltage activated, T-type CaV3 channels. CACHD1 is widely expressed in the central nervo...
A state-of-the-art implementation of a binaural cochlear-implant sound coding strategy inspired by the medial olivocochlear reflex [0.03%]
一种基于中迷路橄榄核反射的双耳人工耳蜗声音编码策略的前沿实现方法研究
Milagros J Fumero,Almudena Eustaquio-Martín,José M Gorospe et al.
Milagros J Fumero et al.
Cochlear implant (CI) users find it hard and effortful to understand speech in noise with current devices. Binaural CI sound processing inspired by the contralateral medial olivocochlear (MOC) reflex (an approach termed the 'MOC strategy') ...
Effects of long-term unilateral cochlear implant use on large-scale network synchronization in adolescents [0.03%]
长期单侧人工耳蜗使用对青少年全脑功能连接的影响研究
Salima Jiwani,Sam M Doesburg,Blake C Papsin et al.
Salima Jiwani et al.
Unilateral cochlear implantation (CI) limits deafness-related changes in the auditory pathways but promotes abnormal cortical preference for the stimulated ear and leaves the opposite ear with little protection from auditory deprivation. In...
Interaction of micropatterned topographical and biochemical cues to direct neurite growth from spiral ganglion neurons [0.03%]
微图案拓扑和生化提示相互作用指导螺旋神经节神经元轴突生长
Kristy Truong,Braden Leigh,Joseph T Vecchi et al.
Kristy Truong et al.
Functional outcomes with neural prosthetic devices, such as cochlear implants, are limited in part due to physical separation between the stimulating elements and the neurons they stimulate. One strategy to close this gap aims to precisely ...
Maurizio Cortada,Loïc Sauteur,Michael Lanz et al.
Maurizio Cortada et al.
Hearing loss affects millions of people worldwide. Yet, there are still no curative therapies for sensorineural hearing loss. Frequent causes of sensorineural hearing loss are due to damage or loss of the sensory hair cells, the spiral gang...
Enhancement of interaural level differences for bilateral cochlear implant users [0.03%]
双侧人工耳蜗植入患者的两耳水平差异增强
Tom Gajecki,Waldo Nogueira
Tom Gajecki
Bilateral cochlear implant (BiCI) users do not localize sounds as well as normal hearing (NH) listeners do. NH listeners rely on two binaural cues to localize sounds in the horizontal plane, namely interaural level differences (ILDs) and in...
Emanuele Perugia,Christopher J Plack,Michael A Stone
Emanuele Perugia
Early signs of noise-induced hearing damage are difficult to identify, as they are often confounded by factors such as age, audiometric thresholds, or even music experience. Much previous research has focused on deficits observed at high in...
Reverberation strength perceived by normal-hearing listeners predictable based on time-varying binaural loudness [0.03%]
基于双耳响度时变特性预测正常听力者对 reverberation 强度的感知
Gregory M Ellis,Pavel Zahorik
Gregory M Ellis
Previous work has explored novel binaural combinations of reverberation and the resulting perceived reverberation strength (reverberance). The present study examines the perceptual effects of additional binaural combinations of reverberatio...
Pitch perception is more robust to interference and better resolved when provided by pulse rate than by modulation frequency of cochlear implant stimulation [0.03%]
脉冲率比耳蜗植入刺激的调制频率对音高感知更有优势
Raymond L Goldsworthy,Andres Camarena,Susan R S Bissmeyer
Raymond L Goldsworthy
Cochlear implants are medical devices that have been used to restore hearing to more than half a million people worldwide. Most recipients achieve high levels of speech comprehension through these devices, but speech comprehension in backgr...
C Röösli,I Dobrev,F Pfiffner
C Röösli
In bone conduction (BC) stimulation, the sound travels from the site of stimulation to the ipsilateral and contralateral cochlea. A frequency dependent reduction in BC hearing sensitivity occurs when sound travels to the contralateral cochl...