Outer hair cell driven reticular lamina mechanical distortion in living cochleae [0.03%]
活体耳蜗外毛细胞驱动的网状层机械变形
G Burwood,W X He,A Fridberger et al.
G Burwood et al.
Cochlear distortions afford researchers and clinicians a glimpse into the conditions and properties of inner ear signal processing mechanisms. Until recently, our examination of these distortions has been limited to measuring the vibration ...
Sofía García-Hernández,María E Rubio
Sofía García-Hernández
The primary startle response (SR) is an innate reaction evoked by sudden and intense acoustic, tactile or visual stimuli. In rodents and humans the SR involves reflexive contractions of the face, neck and limb muscles. The acoustic startle ...
Audiovisual training rapidly reduces potentially hazardous perceptual errors caused by earplugs [0.03%]
视听训练可以快速减少耳塞造成的潜在危险的感知错误
David J Audet,William O Gray,Andrew D Brown
David J Audet
Our ears capture sound from all directions but do not encode directional information explicitly. Instead, subtle acoustic features associated with unique sound source locations must be learned through experience. Surprisingly, aspects of th...
Li Li,Guang-Di Chen,Richard Salvi
Li Li
Background: Levetiracetam (LEV, 5-100 mg/kg) has been shown to prevent audiogenic seizures in a dose-dependent manner. This chemical is known to bind to synaptic vesicle protein 2A and inhibit l-type calcium channels, aff...
Estimating health of the implanted cochlea using psychophysical strength-duration functions and electrode configuration [0.03%]
使用心理物理强度-时间函数和电极配置估算植入耳蜗的健康状况
Soha N Garadat,Deborah J Colesa,Donald L Swiderski et al.
Soha N Garadat et al.
It is generally believed that the efficacy of cochlear implants is partly dependent on the condition of the stimulated neural population. Cochlear pathology is likely to affect the manner in which neurons respond to electrical stimulation, ...
Temporal integration for amplitude modulation in childhood: Interaction between internal noise and memory [0.03%]
儿童时期的幅度调制的时间整合：内部噪声与记忆的相互作用
Laurianne Cabrera,Irene Lorenzini,Stuart Rosen et al.
Laurianne Cabrera et al.
It is still unclear whether the gradual improvement in amplitude-modulation (AM) sensitivity typically found in children up to 10 years of age reflects an improvement in "processing efficiency" (the central ability to use information extrac...
Kazuaki Homma,Satoe Takahashi,Mary Ann Cheatham
Kazuaki Homma
Prestin (SLC26A5) is a membrane-based voltage-dependent motor protein responsible for outer hair cell (OHC) somatic electromotility. Its importance for mammalian cochlear amplification has been demonstrated using mouse models lacking presti...
Phoenix auditory neurons as 3R cell model for high throughput screening of neurogenic compounds [0.03%]
凤头鸟的听神经元作为高通量筛选促神经发生化合物的3R细胞模型
Francis Rousset,Dominik Schmidbauer,Stefan Fink et al.
Francis Rousset et al.
Auditory neurons connect the sensory hair cells from the inner ear to the brainstem. These bipolar neurons are relevant targets for pharmacological intervention aiming at protecting or improving the hearing function in various forms of sens...
Corstiaen P C Versteegh,Evangelia Tserga,Jacopo M Fontana et al.
Corstiaen P C Versteegh et al.
Noise trauma involves a plethora of mechanisms including reactive oxygen species, apoptosis, tissue damage, and inflammation. Recently, circadian mechanisms were also found to contribute to the vulnerability to noise trauma in mice, with gr...
Arthur N Popper,Anthony D Hawkins,Joseph A Sisneros
Arthur N Popper
Investigators working with fish bioacoustics used to refer to fishes that have a narrow hearing bandwidth and poor sensitivity as "hearing generalists" (or "non-specialists"), while fishes that could detect a wider hearing bandwidth and had...