Structural changes in the human stria vascularis induced by aminoglycosides and loop diuretics [0.03%]
氨基糖苷和襻利尿剂诱发的人耳蜗边缘细胞结构变化
Anthony Wright,Andrew Forge,Daniel J Jagger
Anthony Wright
The human stria vascularis has been examined both by scanning and transmission electron microscopy in normal controls and from individuals who had received loop diuretics, aminoglycoside antibiotics or some combination of the two prior to t...
Structural and functional diversity of mitochondria in vestibular/cochlear hair cells and vestibular calyx afferents [0.03%]
前庭/耳蜗毛细胞和前庭爪状afferent的线粒体结构与功能多样性
Anna Lysakowski,Aravind Chenrayan Govindaraju,Robert M Raphael
Anna Lysakowski
Mitochondria supply energy in the form of ATP to drive a plethora of cellular processes. In heart and liver cells, mitochondria occupy over 20% of the cellular volume and the major need for ATP is easily identifiable - i.e., to drive cross-...
Parveen Bazard,Jennifer Pineros,Alejandro A Acosta et al.
Parveen Bazard et al.
Post-translational modifications (PTMs) affect nearly all systems of the human body due to their role in protein synthesis and functionality. These reversible and irreversible modifications control the structure, localization, activity, and...
How much individualization is required to predict the individual effect of suprathreshold processing deficits? Assessing Plomp's distortion component with psychoacoustic detection thresholds and FADE [0.03%]
超阈值处理缺陷的个体效应的预测需要多少个性化？用心理声学检测阈值和FADE评估Plomp的失真成分
David Hülsmeier,Birger Kollmeier
David Hülsmeier
Plomp introduced an empirical separation of the increased speech recognition thresholds (SRT) in listeners with a sensorineural hearing loss into an Attenuation (A) component (which can be compensated by amplification) and a non-compensable...
Animal Models of Hearing Loss after Cochlear Implantation and Electrical Stimulation [0.03%]
人工耳蜗植入及电刺激后听力损失的动物模型研究进展
Lina A J Reiss,Jonathon Kirk,Alexander D Claussen et al.
Lina A J Reiss et al.
Many hearing-impaired patients may significantly benefit from the Hybrid or electro-acoustic stimulation (EAS) cochlear implant (CI). However, as much as 30-55% of CI recipients lose residual hearing after implantation and the potential for...
Modeling temporal information encoding by the population of fibers in the healthy and synaptopathic auditory nerve [0.03%]
健康和突触病理性听神经纤维群体时间信息编码的模型研究
Peter T Johannesen,Thibaud Leclère,Aswin Wijetillake et al.
Peter T Johannesen et al.
We report a theoretical study aimed at investigating the impact of cochlear synapse loss (synaptopathy) on the encoding of the envelope (ENV) and temporal fine structure (TFS) of sounds by the population of auditory nerve fibers. A computat...
Spectro-temporal modulation glimpsing for speech intelligibility prediction [0.03%]
基于光谱时序调制的语音可懂度预测模型研究
Amin Edraki,Wai-Yip Chan,Jesper Jensen et al.
Amin Edraki et al.
We compare two alternative speech intelligibility prediction algorithms: time-frequency glimpse proportion (GP) and spectro-temporal glimpsing index (STGI). Both algorithms hypothesize that listeners understand speech in challenging acousti...
Speech intelligibility prediction based on modulation frequency-selective processing [0.03%]
基于调制频率选择性处理的可懂度预测模型
Helia Relaño-Iborra,Torsten Dau
Helia Relaño-Iborra
Speech intelligibility models can provide insights regarding the auditory processes involved in human speech perception and communication. One successful approach to modelling speech intelligibility has been based on the analysis of the amp...
Mahdie Karbasi,Dorothea Kolossa
Mahdie Karbasi
Various types of methods and approaches are available to predict the intelligibility of speech signals, but many of these still suffer from two major problems: first, their required prior knowledge, which itself could limit the applicabilit...
An overview of the HASPI and HASQI metrics for predicting speech intelligibility and speech quality for normal hearing, hearing loss, and hearing aids [0.03%]
HASPI和HASQI指标综述：正常听力、听力损失及助听器的言语可懂度和清晰度预测概述
James M Kates,Kathryn H Arehart
James M Kates
Alterations of the speech signal, including additive noise and nonlinear distortion, can reduce speech intelligibility and quality. Hearing aids present an especially complicated situation since these devices may implement nonlinear process...