Binaural temporal coding and the middle ear muscle reflex in audiometrically normal young adults [0.03%]
听力学上正常的年轻成人双耳时间编码及中耳肌肉反射
Adnan M Shehabi,Garreth Prendergast,Hannah Guest et al.
Adnan M Shehabi et al.
Noise exposure may damage the synapses that connect inner hair cells with auditory nerve fibers, before outer hair cells are lost. In humans, this cochlear synaptopathy (CS) is thought to decrease the fidelity of peripheral auditory tempora...
The roles of NADPH and isocitrate dehydrogenase in cochlear mitochondrial antioxidant defense and aging [0.03%]
NADPH和异柠檬酸脱氢酶在耳蜗线粒体抗氧化防御及衰老中的作用
Karessa White,Shinichi Someya
Karessa White
Hearing loss is the third most prevalent chronic health condition affecting older adults. Age-related hearing loss affects one in three adults over 65 years of age and is caused by both extrinsic and intrinsic factors, including genetics, a...
Toward a clinically viable spectro-temporal modulation test for predicting supra-threshold speech reception in hearing-impaired listeners [0.03%]
面向临床的谱-时调制测试以预测听损者超阈值言语辨别能力
Johannes Zaar,Lisbeth Birkelund Simonsen,Torsten Dau et al.
Johannes Zaar et al.
The ability of hearing-impaired listeners to detect spectro-temporal modulation (STM) has been shown to correlate with individual listeners' speech reception performance. However, the STM detection tests used in previous studies were overly...
Differences in neural encoding of speech in noise between cochlear implant users with and without preserved acoustic hearing [0.03%]
保留声学听力的耳蜗植入者和无保留声学听力的耳蜗植入者在噪声中言语神经编码差异的研究
Hwan Shim,Subong Kim,Jean Hong et al.
Hwan Shim et al.
Cochlear implants (CIs) have evolved to combine residual acoustic hearing with electric hearing. It has been expected that CI users with residual acoustic hearing experience better speech-in-noise perception than CI-only listeners because p...
Three-dimensional quasi-static displacement of human middle-ear ossicles under static pressure loads: Measurement using a stereo camera system [0.03%]
静态压力载荷下人类中耳听小骨的三维准静态位移：使用立体相机系统进行测量
Birthe Pipping,Ivo Dobrev,Merlin Schär et al.
Birthe Pipping et al.
The time delay and/or malfunctioning of the Eustachian tube may cause pressure differences across the tympanic membrane, resulting in quasi-static movements of the middle-ear ossicles. While quasi-static displacements of the human middle-ea...
The possible role of early-stage phase-locked neural activities in speech-in-noise perception in human adults across age and hearing loss [0.03%]
早期阶段锁相神经活动在成人及不同听力损失人群中噪声中言语感知的可能作用
Guangting Mai,Peter Howell
Guangting Mai
Ageing affects auditory neural phase-locked activities which could increase the challenges experienced during speech-in-noise (SiN) perception by older adults. However, evidence for how ageing affects SiN perception through these phase-lock...
Manipulating the blood labyrinth barrier with mannitol to prevent cisplatin-induced hearing loss [0.03%]
用甘露醇操纵血液迷路屏障以防止顺铂引起的听力损失
Ayesha Noman,Subhendu Mukherjee,Trung N Le
Ayesha Noman
Cisplatin, a chemotherapeutic medication, remains in the cochlea indefinitely, causing permanent hearing loss. Mannitol, a diuretic medication, has been shown to increase the permeability of the blood labyrinth barrier (BLB). We hypothesize...
Richard Salvi,Guang-Di Chen,Senthilvelan Manohar
Richard Salvi
Hyperacusis is a debilitating loudness intolerance disorder that can evoke annoyance, fear and aural facial pain. Although the auditory system seems to be the "central" player, hyperacusis is linked to more than twenty non-auditory medical ...
An emerging role for stress granules in neurodegenerative disease and hearing loss [0.03%]
应力颗粒在神经退行性疾病和听力损失中作用的崭新认识
Jack L Martin,Sally J Dawson,Jonathan E Gale
Jack L Martin
Stress granules (SGs) are membrane-less cytosolic assemblies that form in response to stress (e.g., heat, oxidative stress, hypoxia, viral infection and UV). Composed of mRNA, RNA binding proteins and signalling proteins, SGs minimise stres...
Components of impedance in a cochlear implant animal model with TGFβ1-accelerated fibrosis [0.03%]
具有TGFβ1加速纤维化的耳蜗植入动物模型中的阻抗成分研究
Christopher J Buswinka,Deborah J Colesa,Donald L Swiderski et al.
Christopher J Buswinka et al.
Outcomes of cochlear implantation are likely influenced by the biological state of the cochlea. Fibrosis is a pathological change frequently seen in implanted ears. The goal of this work was to investigate the relationship between fibrosis ...