Combinatorial Atoh1, Gfi1, Pou4f3, and Six1 gene transfer induces hair cell regeneration in the flat epithelium of mature guinea pigs [0.03%]
Atoh1、Gfi1、Pou4f3和Six1基因联合转移诱导成年 Guinea 猪水平耳蜗导管支持细胞转分化为新的感觉毛细胞
Yujie Liu,Lin Yang,Sunita Singh et al.
Yujie Liu et al.
Flat epithelium (FE) is a condition characterized by the loss of both hair cells (HCs) and supporting cells and the transformation of the organ of Corti into a simple flat or cuboidal epithelium, which can occur after severe cochlear insult...
Normal behavioral discrimination of envelope statistics in budgerigars with kainate-induced cochlear synaptopathy [0.03%]
鸡膝酸诱导耳蜗突触病的袋鼠莺的行为统计歧视
Kenneth S Henry,Anna A Guo,Kristina S Abrams
Kenneth S Henry
Cochlear synaptopathy is a common pathology in humans associated with aging and potentially sound overexposure. Synaptopathy is widely expected to cause "hidden hearing loss," including difficulty perceiving speech in noise, but support for...
Peter Bowers,Michael E Ravicz,John J Rosowski
Peter Bowers
We measure bone-conduction (BC) induced skull velocity, sound pressure at the tympanic membrane (TM) and inner-ear compound-action potentials (CAP) before and after manipulating the ear canal, ossicles, and the jaw to investigate the genera...
Making sense of music: Insights from neurophysiology and connectivity analyses in naturalistic listening conditions [0.03%]
音乐的神经科学：自然聆听条件下的洞察与连接分析
Elvira Brattico,Marianna Delussi
Elvira Brattico
According to the latest frameworks, auditory perception and memory involve the constant prediction of future sound events by the brain, based on the continuous extraction of feature regularities from the environment. The neural hierarchical...
Comprehensive behavioral and physiologic assessment of peripheral and central auditory function in individuals with mild traumatic brain injury [0.03%]
轻度脑震荡患者的周围听觉和中枢听觉的功能评估
Amy N Stahl,Jordan M Racca,Cailey I Kerley et al.
Amy N Stahl et al.
Auditory complaints are frequently reported by individuals with mild traumatic brain injury (mTBI) yet remain difficult to detect in the absence of clinically significant hearing loss. This highlights a growing need to identify sensitive in...
Milagros J Fumero,Miriam I Marrufo-Pérez,Almudena Eustaquio-Martín et al.
Milagros J Fumero et al.
Previous studies have shown that in challenging listening situations, people find it hard to equally divide their attention between two simultaneous talkers and tend to favor one talker over the other. The aim here was to investigate whethe...
Head-related transfer functions of rabbits within the front horizontal plane [0.03%]
兔子正面水平平面内的头相关传输函数
Mitchell L Day
Mitchell L Day
The head-related transfer function (HRTF) describes the direction-dependent acoustic filtering by the head that occurs between a source signal in free-field space and the signal at the tympanic membrane. HRTFs contain information on sound s...
Temporal integration of sound motion: Motion-onset response and perception [0.03%]
声音运动的时序整合：运动诱发反应及感知
Lidia B Shestopalova,Ekaterina A Petropavlovskaia,Diana A Salikova et al.
Lidia B Shestopalova et al.
The purpose of our study was to estimate the time interval required for integrating the acoustical changes related to sound motion using both psychophysical and EEG measures. Healthy listeners performed direction identification tasks under ...
NADH improves AIF dimerization and inhibits apoptosis in iPSCs-derived neurons from patients with auditory neuropathy spectrum disorder [0.03%]
NADH可改善线粒体内源性凋亡抑制蛋白(AIF)二聚化并抑制听神经病谱系障碍诱导的 pluripotent干细胞来源神经元凋亡
Yue Qiu,Hongyang Wang,Huaye Pan et al.
Yue Qiu et al.
Auditory neuropathy spectrum disorder (ANSD) is a hearing impairment involving disruptions to inner hair cells (IHCs), ribbon synapses, spiral ganglion neurons (SGNs), and/or the auditory nerve itself. The outcomes of cochlear implants (CI)...
Age-related changes of auditory sensitivity across the life span of CBA/CaJ mice [0.03%]
CBA/CaJ小鼠一生中听敏度的年龄相关变化
Collin R Park,James F Willott,Joseph P Walton
Collin R Park
The inbred mouse strain CBA/CaJ is a frequently used animal model of age-related hearing loss in humans. These mice display significant hearing loss at a relatively advanced age, similar to most humans, with progressive loss of hearing as t...