Electrophysiologically-based electrode selection has the potential to improve speech perception in cochlear-implant users [0.03%]
基于电生理的电极选择有可能提高人工耳蜗使用者的言语感知能力
Wouter David,Elise Verwaerde,Robin Gransier et al.
Wouter David et al.
There is large variability in speech perception outcomes across cochlear-implant (CI) users. One factor that contributes to this variation is the neural modulation encoding in the periphery, which can vary along the implant electrode array....
Multivariate prediction of conductive dysfunction in well and NICU newborns using wideband acoustic immittance with acoustic reflex tests [0.03%]
基于广帯频声导抗和鼓膜反应回避测试预测普通新生儿及NICU新生儿导电功能障碍的研究
Lisa L Hunter,M Patrick Feeney,Denis F Fitzpatrick et al.
Lisa L Hunter et al.
Objectives: The goal of newborn hearing screening is to detect permanent congenital hearing loss. However, the high incidence of middle ear fluid and debris in the ear canal at birth results in only a 5-10% positive predi...
TGF-β signaling regulates flat epithelium formation in severely injured adult mouse utricle through epithelial-mesenchymal transition [0.03%]
转化生长因子β信号通过上皮间质转化调节重度损伤成年小鼠utricle的扁平上皮形成
Wei Su,Lu He,Ming-Yu Hao et al.
Wei Su et al.
Following severe injury, most cells in the vestibular sensory epithelium undergo cell death, whereas the surviving epithelial cells initiate a repair program that leads to the formation of a flat epithelium (FE). However, the mechanisms und...
Membrane scaffolding in auditory hair cells - a molecular tightrope walk enables lateral wall stiffness and flexibility [0.03%]
听觉毛细胞中的膜支架结构——分子张紧素使侧壁既坚固又灵活
Christian Vogl,Victoria C Halim
Christian Vogl
The mammalian cochlea achieves remarkable sensitivity and frequency selectivity through the coordinated function of sensory inner hair cells (IHCs) and electromotile outer hair cells (OHCs). OHCs play a critical role in cochlear amplificati...
Speech-in-noise recognition during hearing protector use: Human performance and acoustic prediction [0.03%]
耳部防护装置使用过程中的噪声环境中语音识别：人因性能和声学预测
Mallory Butler,D J Audet Jr,Carol Sammeth et al.
Mallory Butler et al.
Hearing protection devices (HPDs) are essential safety equipment for workers in noisy settings but can also degrade auditory perception. Some reports have suggested that HPDs can affect speech intelligibility, particularly at low levels, wh...
Miriam Furst,Yonatan Koral,Asaf Zorea
Miriam Furst
Age-related hearing loss arises from multiple cochlear pathologies. However, linking audiometric thresholds to their underlying cellular mechanisms remains a challenge. We present a biophysically grounded framework linking audiograms to the...
Cochlear size variation in a large-scale international multicentre cohort [0.03%]
大规模国际多中心队列中耳蜗大小的变异
Andrea Schreier,Mario Zernotti,Aanand Acharya et al.
Andrea Schreier et al.
Aim: This study aims to (1) review the literature on cochlear size, measured by the A-value, to assess reported variation across studies, and (2) consolidate cochlear parameters-specifically basal turn diameter (A-value) ...
Estimation of minor-to-moderate conductive hearing loss with distortion-product otoacoustic emissions in humans [0.03%]
人耳轻至中度传导性听力损失的失真产物耳声发射估计研究
Katharina Bader,Stephan Kempa,Philipp Graff et al.
Katharina Bader et al.
Distortion-product otoacoustic emission (DPOAE) level maps provide a three-dimensional, frequency-specific representation of cochlear nonlinearities and offer an objective tool to estimate conductive hearing loss (CHL). While previous exper...
Effects of early hearing deficits on olivocochlear efferent neuron morphology in mice [0.03%]
小鼠早期听力损伤对耳蜗背侧橄榄核神经元形态的影响
Kirupa Suthakar,Hannah Douglas-Kinniburgh,David K Ryugo
Kirupa Suthakar
One of the fundamental features of age-related hearing loss is difficulty discriminating signals in the presence of background noise, a functional deficit that may be related to the loss of auditory efferent neurons. We hypothesize that the...
Cochlear aging after synaptopathic noise: age-noise interactions in hair cell loss and axonal degeneration [0.03%]
暴露噪音后的耳蜗老化：年龄与噪声对毛细胞丢失和轴突变性的影响
Serhii Kostrikov,Jens Hjortkjaer,Torsten Dau et al.
Serhii Kostrikov et al.
Despite many studies of cochlear synaptic loss and/or recovery after acoustic injury, none has followed degeneration of auditory-nerve fiber (ANF) peripheral axons - a critical knowledge gap in the context of regenerative strategies. We exp...