A novel mouse model of acute vestibular dysfunction via semicircular canal injection of absolute ethanol [0.03%]
通过半规管注射绝对酒精构建急性前庭功能障碍小鼠模型的新方法
Pei Zhou,Jing Wang,Yuwei Zhang et al.
Pei Zhou et al.
Objective: Various vestibular pathology models have been developed to elucidate the underlying mechanisms of vestibular diseases; however, there is a notable absence of minimally invasive mouse model of vestibular dysfunc...
Application progress of Tubomanometry (TMM) in Eustachian tube function evaluation: A review [0.03%]
tubomanometry(TMM)在咽鼓管功能评价中的应用进展：综述
Qianling Su,Ruichun Chen,Jingqun Mo et al.
Qianling Su et al.
The Eustachian tube (ET) plays a pivotal role in preserving normal auditory function by regulating middle ear (ME) air pressure, facilitating the drainage of secretions from the tympanic cavity, and preventing retrograde infection by pathog...
The inner ear of the Port Jackson shark, Heterodontus portusjacksoni: morphometric analysis using bioimaging and phalloidin staining [0.03%]
霍加顿氏湾角鲨(Heterodontus portusjacksoni)内耳的生物影像及菲鹤豆素染色形态计量分析
H Robins,L Chapuis,C C Kerr et al.
H Robins et al.
The inner ear plays a crucial role in detecting sound and maintaining balance in elasmobranchs, yet its morphology and function remain poorly understudied compared to teleosts. This study provides the first detailed morphometric analysis of...
Julia Veloso de Oliveira,Nora M Weiss,Wilhelm Wimmer
Julia Veloso de Oliveira
Impedance telemetry is a routine procedure in cochlear implant care, providing insights into the electrode-tissue interface. Analyzing its electrical characteristics helps assess patient outcomes by accounting for implant-specific and tissu...
Prevention of aminoglycoside-induced outer hair cell loss by silencing CaMKKβ in an acute mouse model [0.03%]
沉默CaMKKβ预防氨基糖苷致急性小鼠耳蜗外毛细胞损失的作用及机制研究
Fan Wu,Shan Xu,Hongguo Su et al.
Fan Wu et al.
The use of ototoxic drugs remains a common cause of acquired hearing loss worldwide. Among them, aminoglycoside antibiotics are still widely used in clinical practice. Although the pathological mechanisms underlying aminoglycoside-induced h...
Optimization of the Yacovino maneuver for superior canal BPPV using numerical simulations [0.03%]
数值模拟优化Yacovino操使矫正 Superior 眨眼管BPPV
Ismael Arán-Tapia,Guillermo Bastos,Alberto P Muñuzuri
Ismael Arán-Tapia
We evaluated the effectiveness of the original Yacovino maneuver (YM) for treating superior canal benign paroxysmal positional vertigo (SC-BPPV) using numerical simulations and proposed modifications to enhance its efficacy. A high-resoluti...
Neural tracking of continuous speech in adverse acoustic conditions among healthy adults with normal hearing and hearing loss: A systematic review [0.03%]
正常听力和听力损失的健康成人不利声学条件下连续言语的神经追踪：系统评价研究
David Ratelle,Pascale Tremblay
David Ratelle
The study of neural speech tracking (NST) has gained increasing attention in the field of auditory neuroscience in recent years. However, its contribution to speech perception in noise (SPiN), especially regarding aging and hearing loss, ha...
BRCA1 deficiency promotes DNA damage in cochlear hair cells with activation of ATM-p53 pathway independent of CHK2 [0.03%]
BRCA1缺陷通过激活独立于CHK2的ATM-p53途径促进耳蜗毛细胞DNA损伤
Weitao Jiang,Feng Bai,Guanrun Wang et al.
Weitao Jiang et al.
Platinum-based chemotherapy drugs, including cisplatin (CDDP), are known to cause irreversible hearing loss. We recently discovered that BRCA1 facilitates the repair of CDDP-induced DNA double-strand breaks (DSBs) in cochlear hair cells (HC...
Machine learning identification of tinnitus-related features in auditory peripheral spontaneous activity in a guinea pig noise-induced tinnitus model [0.03%]
基于机学习的噪声诱发 Guinea Pig 模型耳蜗自发性活动的鉴别特征分析研究(tinnitus 相关指标)
Linhan Huang,Min Chen,Shuwen Fan et al.
Linhan Huang et al.
Objectives: Tinnitus affects millions globally, yet its clinical assessment relies on subjective reports, limiting diagnostic accuracy and treatment development. This study aimed to identify objective, tinnitus-related fe...
Hearing function and ossicular deformities and fractures in the oim mouse model of brittle bone disease [0.03%]
听觉功能和OIM鼠模型脆骨病 ossicular畸形和骨折
Maialen Ugarteburu,Aliah F Shaheen,Christoph Rau et al.
Maialen Ugarteburu et al.
Hearing loss is a prevalent symptom of osteogenesis imperfecta (OI), a group of collagen type I-related skeletal disorders, commonly known as brittle bone disease. Clinical manifestation of hearing loss in OI often presents with stapes foot...