Surface electrical stimulation of the auditory cortex preserves efferent medial olivocochlear neurons and reduces cochlear traits of age-related hearing loss [0.03%]
听皮层表面电刺激可保存耳蜗发出的中 Olivocochlear 神经元并减少与年龄相关的听力损失的耳蜗特征
V Fuentes-Santamaría,Z Benítez-Maicán,J C Alvarado et al.
V Fuentes-Santamaría et al.
The auditory cortex is the source of descending connections providing contextual feedback for auditory signal processing at almost all levels of the lemniscal auditory pathway. Such feedback is essential for cognitive processing. It is like...
L-Ergothioneine slows the progression of age-related hearing loss in CBA/CaJ mice [0.03%]
L-耳舒肽延缓CBA/CaJ小鼠年龄相关性听力损失的进展
Mark A Bauer,Parveen Bazard,Alejandro A Acosta et al.
Mark A Bauer et al.
The naturally occurring amino acid, l-ergothioneine (EGT), has immense potential as a therapeutic, having shown promise in the treatment of other disease models, including neurological disorders. EGT is naturally uptaken into cells via its ...
Two are better than one: Differences in cortical EEG patterns during auditory and visual verbal working memory processing between Unilateral and Bilateral Cochlear Implanted children [0.03%]
双则优于单：单侧和双侧人工耳蜗植入儿童在听觉和视觉言语工作记忆处理过程中的皮层EEG模式差异
Bianca Maria Serena Inguscio,Giulia Cartocci,Nicolina Sciaraffa et al.
Bianca Maria Serena Inguscio et al.
Despite the proven effectiveness of cochlear implant (CI) in the hearing restoration of deaf or hard-of-hearing (DHH) children, to date, extreme variability in verbal working memory (VWM) abilities is observed in both unilateral and bilater...
Comparative Study
Hearing research. 2024 May:446:109007. DOI:10.1016/j.heares.2024.109007 2024
Electrocochleographic frequency-following responses as a potential marker of age-related cochlear neural degeneration [0.03%]
电致听觉反应作为潜在的年龄相关性耳蜗神经变性的标志物
Miguel Temboury-Gutierrez,Jonatan Märcher-Rørsted,Michael Bille et al.
Miguel Temboury-Gutierrez et al.
Auditory nerve (AN) fibers that innervate inner hair cells in the cochlea degenerate with advancing age. It has been proposed that age-related reductions in brainstem frequency-following responses (FFR) to the carrier of low-frequency, high...
Comparative Study
Hearing research. 2024 May:446:109005. DOI:10.1016/j.heares.2024.109005 2024
Characteristics of spatial protein expression in the mouse cochlear sensory epithelia: Implications for age-related hearing loss [0.03%]
小鼠耳蜗感觉上皮蛋白质空间表达特征：对年龄相关听力损失的启示
Huilin Lao,Yafeng Zhu,Mei Yang et al.
Huilin Lao et al.
Hair cells in the cochlear sensory epithelia serve as mechanosensory receptors, converting sound into neuronal signals. The basal sensory epithelia are responsible for transducing high-frequency sounds, while the apex handles low-frequency ...
Intraoperative assessment of cochlear nerve functionality in various vestibular schwannoma scenarios: Lessons learned [0.03%]
术中内听道不同位置 schwannoma 手术对听神经功能影响的评估
Luis Lassaletta,Miryam Calvino,Miguel Díaz et al.
Luis Lassaletta et al.
The use of cochlear implants (CIs) is on the rise for patients with vestibular schwannoma (VS). Besides CI following tumor resection, new scenarios such as implantation in observed and/or irradiated tumors are becoming increasingly common. ...
Noise-induced synaptic loss and its post-exposure recovery in CBA/CaJ vs. C57BL/6J mice [0.03%]
CBA/CaJ和C57BL/6J小鼠的噪声诱导突触丢失及其暴露后的恢复效应
Pei-Zhe Wu,Leslie D Liberman,M Charles Liberman
Pei-Zhe Wu
Acute noise-induced loss of synapses between inner hair cells (IHCs) and auditory nerve fibers (ANFs) has been documented in several strains of mice, but the extent of post-exposure recovery reportedly varies dramatically. If such inter-str...
Towards universal access: A review of global efforts in ear and hearing care [0.03%]
走向普遍享有：全球听力照护工作综述
Rolvix H Patterson,Olayinka Suleiman,Racheal Hapunda et al.
Rolvix H Patterson et al.
Hearing loss affects 1.6 billion people worldwide and disproportionately affects those in low- and middle-income countries. Despite being largely preventable or treatable, ear and hearing conditions result in significant and lifelong morbid...
Geoffrey A Manley,Bert Maat,Sabine Begall et al.
Geoffrey A Manley et al.
African mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit d...
The crucial role of diverse animal models to investigate cochlear aging and hearing loss [0.03%]
探讨听力损失和耳蜗衰老的多种动物模型的关键作用
Karen Castaño-González,Christine Köppl,Sonja J Pyott
Karen Castaño-González
Age-related hearing loss affects a large and growing segment of the population, with profound impacts on quality of life. Age-related pathology of the cochlea-the mammalian hearing organ-underlies age-related hearing loss. Because investiga...