Low level of expression of known deafness genes Kcne1, Kcnj10 or Col4a3 is sufficient to maintain hearing in mice [0.03%]
小鼠已知听力损失基因Kcne1、Kcnj10或Col4a3低表达足以保持听力
Darcey A Kirwin,Nina Treder,Elisa Martelletti et al.
Darcey A Kirwin et al.
Kcne1, Kcnj10 and Col4a3 are all expressed in the stria vascularis where they serve critical roles in generating the endocochlear potential. Mutations in any of these three genes are linked to human deafness syndromes for which there are cu...
Exploring the effect of cadaver head fixation in bone conduction hearing: Insights from finite element modeling [0.03%]
基于有限元模型的人头固定对骨导听觉影响的研究
Jongwoo Lim,Hyun Seong Shin,Ivo Dobrev et al.
Jongwoo Lim et al.
This study investigates the effects of head fixation method on bone conduction (BC) responses using a full head finite element model validated against experimental data. Boundary constraint variables, including fixation strength, location, ...
Effect of stimulus level on speech masking by multitalker noise in a cochlear model [0.03%]
多说话人噪声掩蔽下耳蜗模型中言语识别的困难度与刺激强度的关系研究
Václav Vencovský,Zbyněk Bureš
Václav Vencovský
Previous research shows that intelligibility of speech in noise (SIN) with a constant speech-to-noise ratio (SNR) changes in dependence on overall stimulus level. It has been hypothesized that these changes were associated with nonlinear re...
Investigation of intracochlear electrical fields with spread of excitation and voltage matrix in cochlear implant users and their link to speech perception [0.03%]
电位矩阵和兴奋扩散的颅内电场在人工耳蜗使用者身上的研究及其与言语感知的关系
Pascal Nachtigäller,Tobias Weissgerber,Uwe Baumann et al.
Pascal Nachtigäller et al.
Background: Objective measures and their relation to listening performance are of interest in the study of cochlear implants (CIs). Both spread of excitation (SoE) and the voltage matrix (VM) are objective descriptors of ...
Monocyte-dependent innate immunity prevents severe complications of acute bacterial infection in the middle ear in a murine model [0.03%]
单核细胞依赖的先天性免疫可防止小鼠急性细菌性中耳炎严重并发症发生
Seong Hoon Bae,Heang Ran Park,Hyoyeol Kim et al.
Seong Hoon Bae et al.
Introduction: Acute otitis media (AOM) is a common middle ear infection. The role of immune cells, particularly monocytes, in preventing complications of AOM remains unclear. Therefore, this study aimed to investigate the...
Deep learning models for predicting hearing thresholds based on joint stimulus-frequency otoacoustic emissions and distortion-product otoacoustic emissions [0.03%]
基于联合刺激频率性耳声发射和差频性耳声发射的听力阈值深度学习预测模型
Runyi Xu,Qin Gong
Runyi Xu
According to the dual-source generation hypothesis, stimulus-frequency otoacoustic emissions (SFOAEs) and distortion-product OAEs (DPOAEs) arise from different cochlear mechanisms, and both are capable of characterizing hearing loss. Howeve...
Role of risk factors and their variable types in predicting noise-induced hearing loss using artificial intelligence algorithms [0.03%]
风险因素及其变量类型在利用人工智能算法预测噪声性听力损失中的作用
Zhengheng Zhang,Longteng Jiang,Meibian Zhang et al.
Zhengheng Zhang et al.
Early prediction and warning of occupational noise-induced hearing loss (NIHL) in workers is critical. This study aimed to explore the role of risk factors and their variable types to NIHL prediction through machine learning (ML) techniques...
Predicting variability in pediatric cochlear implant outcomes through synchronous brain activation patterns: Insights from fNIRS [0.03%]
基于脑激活模式预测儿童人工耳蜗植入术预后变异度：近红外光谱成像的新视野
Hsueh-Ching Tseng,Huei-Mei Liu,Pei-Hsuan Lin et al.
Hsueh-Ching Tseng et al.
Objectives: This study examined the relationship between cortical activation and auditory performance in pediatric cochlear implant (CI) users compared to normal-hearing (NH) controls using functional near-infrared spectr...
Eye movement-related eardrum oscillations do not require current visual input [0.03%]
眼睛运动引起的鼓膜振动无需当前视觉输入
Hossein Abbasi,Cynthia D King,Stephanie Lovich et al.
Hossein Abbasi et al.
Oculomotor signals influence the neural processing of auditory input. Recent studies have shown that this connection extends to the auditory periphery: The phase and amplitude of eardrum oscillations was systematically influenced by eye mov...
Promoter polymorphism rs510432 in ATG5 affects the susceptibility of noise-induced hearing loss by altering the binding of C/EBPβ [0.03%]
ATG5基因启动子多态性rs510432通过影响C/EBPβ的结合从而影响噪声性听力损失的易感性
Long Miao,Man Qu,Yu Xue et al.
Long Miao et al.
Noise-induced hearing loss (NIHL) is an occupational-related disease characterized by progressive sensorineural hearing impairment. Autophagy is thought as a key pathway mediated by highly conserved autophagy-related genes (ATGs) and plays ...