Julia Veloso de Oliveira,Nora M Weiss,Wilhelm Wimmer
Julia Veloso de Oliveira
Impedance telemetry is a routine procedure in cochlear implant care, providing insights into the electrode-tissue interface. Analyzing its electrical characteristics helps assess patient outcomes by accounting for implant-specific and tissu...
Prevention of aminoglycoside-induced outer hair cell loss by silencing CaMKKβ in an acute mouse model [0.03%]
沉默CaMKKβ预防氨基糖苷致急性小鼠耳蜗外毛细胞损失的作用及机制研究
Fan Wu,Shan Xu,Hongguo Su et al.
Fan Wu et al.
The use of ototoxic drugs remains a common cause of acquired hearing loss worldwide. Among them, aminoglycoside antibiotics are still widely used in clinical practice. Although the pathological mechanisms underlying aminoglycoside-induced h...
Optimization of the Yacovino maneuver for superior canal BPPV using numerical simulations [0.03%]
数值模拟优化Yacovino操使矫正 Superior 眨眼管BPPV
Ismael Arán-Tapia,Guillermo Bastos,Alberto P Muñuzuri
Ismael Arán-Tapia
We evaluated the effectiveness of the original Yacovino maneuver (YM) for treating superior canal benign paroxysmal positional vertigo (SC-BPPV) using numerical simulations and proposed modifications to enhance its efficacy. A high-resoluti...
Neural tracking of continuous speech in adverse acoustic conditions among healthy adults with normal hearing and hearing loss: A systematic review [0.03%]
正常听力和听力损失的健康成人不利声学条件下连续言语的神经追踪：系统评价研究
David Ratelle,Pascale Tremblay
David Ratelle
The study of neural speech tracking (NST) has gained increasing attention in the field of auditory neuroscience in recent years. However, its contribution to speech perception in noise (SPiN), especially regarding aging and hearing loss, ha...
BRCA1 deficiency promotes DNA damage in cochlear hair cells with activation of ATM-p53 pathway independent of CHK2 [0.03%]
BRCA1缺陷通过激活独立于CHK2的ATM-p53途径促进耳蜗毛细胞DNA损伤
Weitao Jiang,Feng Bai,Guanrun Wang et al.
Weitao Jiang et al.
Platinum-based chemotherapy drugs, including cisplatin (CDDP), are known to cause irreversible hearing loss. We recently discovered that BRCA1 facilitates the repair of CDDP-induced DNA double-strand breaks (DSBs) in cochlear hair cells (HC...
Machine learning identification of tinnitus-related features in auditory peripheral spontaneous activity in a guinea pig noise-induced tinnitus model [0.03%]
基于机学习的噪声诱发 Guinea Pig 模型耳蜗自发性活动的鉴别特征分析研究(tinnitus 相关指标)
Linhan Huang,Min Chen,Shuwen Fan et al.
Linhan Huang et al.
Objectives: Tinnitus affects millions globally, yet its clinical assessment relies on subjective reports, limiting diagnostic accuracy and treatment development. This study aimed to identify objective, tinnitus-related fe...
Hearing function and ossicular deformities and fractures in the oim mouse model of brittle bone disease [0.03%]
听觉功能和OIM鼠模型脆骨病 ossicular畸形和骨折
Maialen Ugarteburu,Aliah F Shaheen,Christoph Rau et al.
Maialen Ugarteburu et al.
Hearing loss is a prevalent symptom of osteogenesis imperfecta (OI), a group of collagen type I-related skeletal disorders, commonly known as brittle bone disease. Clinical manifestation of hearing loss in OI often presents with stapes foot...
TRPA1 deficiency affects cochlear potentials days after noise exposure [0.03%]
TRPA1缺失在噪声暴露后的若干天影响耳蜗电位
Samantha A Radomski,D Susana Llanes-Coronel,Ava M Kruse et al.
Samantha A Radomski et al.
TRPA1 channels are master sensors of tissue damage. We recently showed that, after acoustic trauma, TRPA1 activation in cochlear supporting cells regulates hearing sensitivity and is a component of the temporary threshold shift. In the neon...
Moderate presbycusis boosts audio-visual integration, but not lip-reading [0.03%]
中度听力受损加强了视听整合，但不影响唇读能力
Tanguy Delmas,Mathieu Pham Van Cang,Grégory Gerenton et al.
Tanguy Delmas et al.
In audiological practice, speech comprehension is typically assessed in the auditory modality alone (speech in quiet or noise). However, in real-life communication when the auditory input is degraded - due to noise or hearing loss (HL) - in...
Investigating the causal relationship between circulating inflammatory proteins and tinnitus: Insights from a Mendelian Randomization study [0.03%]
基于孟德尔随机化研究探讨循环炎症蛋白与耳鸣之间的因果关系
Shichun He,Meiqi Wei,Deyu Meng et al.
Shichun He et al.
Tinnitus, a condition characterized by the perception of ringing in the ears, significantly impacts quality of life, yet its underlying biological mechanisms remain poorly understood. Emerging evidence suggests a role for inflammation in ti...