Neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets [0.03%]
基底前脑胆碱能损伤后雪貂初级听皮层的神经处理过程
Fernando R Nodal,Nicholas D Leach,Peter Keating et al.
Fernando R Nodal et al.
Cortical acetylcholine (ACh) release has been linked to various cognitive functions, including perceptual learning. We have previously shown that cortical cholinergic innervation is necessary for accurate sound localization in ferrets, as w...
Neurometric amplitude modulation detection in the inferior colliculus of Young and Aged rats [0.03%]
年轻和老年大鼠脑下丘神经计量幅度检测能力的改变
Edward L Bartlett,Emily X Han,Aravindakshan Parthasarathy
Edward L Bartlett
Amplitude modulation is an important acoustic cue for sound discrimination, and humans and animals are able to detect small modulation depths behaviorally. In the inferior colliculus (IC), both firing rate and phase-locking may be used to d...
Comparative Study
Hearing research. 2024 Jun:447:109028. DOI:10.1016/j.heares.2024.109028 2024
Changes in visually and auditory attended audiovisual speech processing in cochlear implant users: A longitudinal ERP study [0.03%]
人工耳蜗植入者的视听语音处理的纵向研究中的变化
Anna Weglage,Natalie Layer,Hartmut Meister et al.
Anna Weglage et al.
Limited auditory input, whether caused by hearing loss or by electrical stimulation through a cochlear implant (CI), can be compensated by the remaining senses. Specifically for CI users, previous studies reported not only improved visual s...
Asymmetric pulses delivered by a cochlear implant allow a reduction in evoked firing rate and in spatial activation in the guinea pig auditory cortex [0.03%]
不对称电脉冲能够降低豚鼠听皮层神经元的诱发放电率和空间激活范围
V Adenis,E Partouche,P Stahl et al.
V Adenis et al.
Despite that fact that the cochlear implant (CI) is one of the most successful neuro-prosthetic devices which allows hearing restoration, several aspects still need to be improved. Interactions between stimulating electrodes through current...
Susceptibility of mouse cochlear hair cells to cisplatin ototoxicity largely depends on sensory mechanoelectrical transduction channels both Ex Vivo and In Vivo [0.03%]
小鼠耳蜗毛细胞的顺铂敏感性主要依赖于离体和在体感觉机械机电转化通道的存在
Ayako Maruyama,Yoshiyuki Kawashima,Yoko Fukunaga et al.
Ayako Maruyama et al.
Cisplatin, a highly effective chemotherapeutic drug for various human cancers, induces irreversible sensorineural hearing loss as a side effect. Currently there are no highly effective clinical strategies for the prevention of cisplatin-ind...
Quantitative profiling of cochlear synaptosomal proteins in cisplatin-induced synaptic dysfunction [0.03%]
顺铂引起的突触损伤的耳蜗突触体蛋白定量分析
Monazza Shahab,Rita Rosati,Paul M Stemmer et al.
Monazza Shahab et al.
The disruption of ribbon synapses in the cochlea impairs the transmission of auditory signals from the cochlear sensory receptor cells to the auditory cortex. Although cisplatin-induced loss of ribbon synapses is well-documented, and studie...
Tumors of the nervous system and hearing loss: Beyond vestibular schwannomas [0.03%]
神经系统肿瘤与听力损失：不止是听神经瘤
Carmen Ruiz-García,Luis Lassaletta,Pilar López-Larrubia et al.
Carmen Ruiz-García et al.
Hearing loss is a common side effect of many tumor treatments. However, hearing loss can also occur as a direct result of certain tumors of the nervous system, the most common of which are the vestibular schwannomas (VS). These tumors arise...
Murine cochlear damage models in the context of hair cell regeneration research [0.03%]
听觉毛细胞再生研究中的小鼠耳蜗损伤模型
Ayse Maraslioglu-Sperber,Fabian Blanc,Stefan Heller
Ayse Maraslioglu-Sperber
Understanding the complex pathologies associated with hearing loss is a significant motivation for conducting inner ear research. Lifelong exposure to loud noise, ototoxic drugs, genetic diversity, sex, and aging collectively contribute to ...
Biophysics-inspired spike rate adaptation for computationally efficient phenomenological nerve modeling [0.03%]
受生物物理启发的脉冲速率自适应在计算有效的神经元现象学建模中的应用
Jacob de Nobel,Savine S M Martens,Jeroen J Briaire et al.
Jacob de Nobel et al.
This study introduces and evaluates the PHAST+ model, part of a computational framework designed to simulate the behavior of auditory nerve fibers in response to the electrical stimulation from a cochlear implant. PHAST+ incorporates a high...
Motor, somatosensory, and executive cortical areas elicit monosynaptic and polysynaptic neuronal activity in the auditory midbrain [0.03%]
motor、躯体感觉和执行皮层区诱发听脑干的单突触和多突触神经元活动
Sarah E Gartside,Bas Mj Olthof,Adrian Rees
Sarah E Gartside
We recently reported that the central nucleus of the inferior colliculus (the auditory midbrain) is innervated by glutamatergic pyramidal cells originating not only in auditory cortex (AC), but also in multiple 'non-auditory' regions of the...