Critical role of hepsin/TMPRSS1 in hearing and tectorial membrane morphogenesis: Insights from transgenic mouse models [0.03%]
肝素酶/TMPRSS1在听力和顶膜形态发生中的关键作用：来自转基因小鼠模型的启示
Ting-Hua Yang,Yu-Chen Hsu,Peng Yeh et al.
Ting-Hua Yang et al.
Mutations in various type II transmembrane serine protease (TMPRSS) family members are associated with non-syndromic hearing loss, with some mechanisms still unclear. For instance, the mechanism underlying profound hearing loss and tectoria...
Resting-state networks in chronic tinnitus: Increased connectivity between thalamus and visual areas [0.03%]
慢性耳鸣的静息态网络重联：丘脑和视觉区域之间的功能连接增加
Tori Kok,Rosemary Varley,Chris Clark et al.
Tori Kok et al.
Tinnitus is thought to be associated with aberrant spontaneous activity in the central nervous system. Previous resting-state fMRI findings support this hypothesis and have shown a variety of alterations in neural activity in people with ti...
Gene therapy for hearing loss: Current status and future prospects of non-viral vector delivery systems [0.03%]
非病毒载体递送系统在基因治疗感音神经性听力损失中的现状及未来前景展望
Jean-Christophe Leclère,Remi Marianowski,Tristan Montier
Jean-Christophe Leclère
Current therapeutic options for hearing loss rely on hearing aids, ossiculoplasty or cochlear implants. These devices have limitations, particularly in noisy acoustic environments. Therefore, interest in exploring aetiological treatments to...
A simple electrical circuit model for impedance spectroscopy with cochlear implant electrodes [0.03%]
一种用于人工耳蜗电极阻抗谱测量的简单电路模型
Merle Sehlmeyer,Mit B Bhavsar,Stefan Zimmermann et al.
Merle Sehlmeyer et al.
Although cochlear implants are an established method of restoring hearing, they can have limitations such as increasing current spread and decreasing frequency resolution due to tissue growth around the electrode array. Impedance measuremen...
No causal relationship serum lipids on age-related hearing loss based on Mendelian randomized evidence [0.03%]
基于孟德尔随机化的证据表明血脂与年龄相关性听力损失无因果关系
Tianyi Ni,Ziyu Shen,Xiuling Lu et al.
Tianyi Ni et al.
Objectives: Presbycusis, or age-related hearing loss (ARHL) has been a common disability disease among the elderly population. It is particularly essential to identify the underlying role of related risk factors for ARHL ...
Conductance properties of the α9α10 nicotinic acetylcholine receptor of neonatal mouse inner and outer hair cells [0.03%]
新生小鼠内、外毛细胞α9α10型乙酰胆碱受体的电导性质研究
Helen J Kennedy,Michael G Evans
Helen J Kennedy
In the developing cochlea, just before the onset of hearing on postnatal day 12, the medial olivocochlear efferent axons in synaptic contact with the inner hair cells (IHCs) start withdrawing and new efferent synaptic connections are formed...
Frequency dependence and harmonic distortion of stapes displacement and intracochlear pressure in response to very high level sounds [0.03%]
高强度声音刺激下听骨链足 process 和耳蜗内压力的频响及谐波失真研究
Nathaniel T Greene,Theodore F Argo,James Easter et al.
Nathaniel T Greene et al.
Previous reports have suggested that intracochlear pressures (PIC) measured at the base of the cochlea increase directly proportionally with stapes displacement (DStap) in response to moderately high (
Cross-sectional screening for inflammation in tinnitus with near-normal hearing [0.03%]
耳鸣的横断面筛查（近乎正常听力下的炎症）
Lilian M Mennink,Lina B M Albakri,Marlien W Aalbers et al.
Lilian M Mennink et al.
Tinnitus is the perception of sound without an external stimulus. Recently, inflammation has been implicated in the pathophysiology of tinnitus. In tinnitus animal models, cytokine levels are increased throughout the whole auditory pathway,...
Auditory changes in awake guinea pigs exposed to overcompressed music [0.03%]
暴露在过度压缩音乐中的清醒 Guinea Pig 的听觉变化
Thamara Suzi Dos Santos,Pierrick Bordiga,Paul Avan
Thamara Suzi Dos Santos
Exposure to loud sound during leisure time is identified as a significant risk factor for hearing by health authorities worldwide. The current standard that defines unsafe exposure rests on the equal-energy hypothesis, according to which th...
The effect of acoustically enriched environment on structure and function of the developing auditory system [0.03%]
声学丰富环境对发育听觉系统结构和功能的影响
Zbyněk Bureš,Jana Svobodová Burianová,Kateryna Pysanenko et al.
Zbyněk Bureš et al.
It has long been known that environmental conditions, particularly during development, affect morphological and functional properties of the brain including sensory systems; manipulating the environment thus represents a viable way to explo...