Hearing restoration through hair cell regeneration: A review of recent advancements and current limitations [0.03%]
通过毛细胞再生恢复听力：近期进展和当前限制的综述
Melissa M McGovern,Brandon C Cox
Melissa M McGovern
Hearing loss is extremely common, yet limited treatment options are available to restore hearing, and those that are available provide incomplete recovery of hearing detection. For patients who are born with normal hearing, the most common ...
Optimizing the stimulus used to elicit the acoustic change complex: Evaluation of the pre-transition stimulus duration and stimulus complexity in normal hearing adults [0.03%]
优化用于引发声学变化复合反应的刺激：评估正常听力成人中的过渡前刺激时长和刺激复杂度
Laura I A Schellekens,Marloes L Adank,Sarah Meehan et al.
Laura I A Schellekens et al.
Introduction: The Acoustic Change Complex (ACC), a cortical auditory evoked potential elicited by sound changes, is a promising measure of speech discrimination for populations unable to perform speech perception tests. H...
Dan Luo,Ji Liu,Ryszard Auksztulewicz et al.
Dan Luo et al.
Detecting patterns, and noticing unexpected pattern changes, in the environment is a vital aspect of sensory processing. Adaptation and prediction error responses are two components of neural processing related to these tasks, and previous ...
Dzmitry Vaido,Martín A Toderi,Dolores Bozovic
Dzmitry Vaido
Hair cells play a critical role in the auditory system, acting as key agents in active sound detection. Studying living hair cells ex vivo provides valuable insights into the mechanisms underlying sound detection. In this study, we investig...
The relationship between interaural coherence, interaural level differences, and binaural fusion [0.03%]
双耳相干性，双耳强度差与双耳融合的关系
Justin M Aronoff,Josephine R LaPapa,Jordan Deutsch
Justin M Aronoff
Binaural fusion is the perception of a single auditory image when signals are presented to the two ears. Decreasing the interaural coherence of the signals often degrades binaural fusion. However, perception of interaural level differences ...
The relationship between auditory brainstem responses, cognitive ability, and speech-in-noise perception among young adults with normal hearing thresholds [0.03%]
正常听力阈值的青年人中听觉脑干反应、认知能力以及噪声中的语音感知之间的关系
Mishaela DiNino,Jenna Crowell,Ilsa Kloiber et al.
Mishaela DiNino et al.
The goal of this research was to determine the contributions of auditory neural processing and cognitive abilities to predict performance on a speech-in-noise perception task in young, normal hearing adults. Two experiments were performed, ...
Influence of visual analogue of speech envelope, formants, and word onsets on word recognition is not pronounced [0.03%]
语音包络、共振峰和单词起始对词汇识别的影响不明显
Kaja Rosa Benz,Anne Hauswald,Nathan Weisz
Kaja Rosa Benz
In noisy environments, filtering out the relevant speech signal from the background noise is a major challenge. Visual cues, such as lip movements, can improve speech understanding. This suggests that lip movements carry information about s...
Cochlear health in a cohort of cochlear implant users carrying the p.Pro51Ser variant in the COCH gene (DFNA9): A cross-sectional study evaluating the changes in the electrically evoked compound action potential (eCAP) [0.03%]
携带COCH基因(p.Pro51Ser变体)的耳蜗植入使用者队列中的耳蜗健康：一项横断面研究，评估电诱发复合动作电位(eCAP)的变化
Julie Moyaert,Annick Gilles,Dyan Ramekers et al.
Julie Moyaert et al.
The present study focuses on DFNA9, an autosomal dominant disorder caused by pathogenic variants in the COCH gene. These mutations induce the formation of aggregates that are toxic to the fibrocytes in the extracellular matrix, ultimately l...
Evaluating the role of age on speech-in-noise perception based primarily on temporal envelope information [0.03%]
基于听觉-envelope信息评估年龄在噪声中语音感知中的作用
Jonathan Regev,Andrew J Oxenham,Helia Relaño-Iborra et al.
Jonathan Regev et al.
Acoustic amplitude modulation (AM) patterns carry important information, particularly in speech. AM masking, influenced by frequency selectivity in the modulation domain, is considered a crucial factor for speech intelligibility in noisy en...
Mammalian TMC1 or 2 are necessary for scramblase activity in auditory hair cells [0.03%]
哺乳动物的TMC1或TMC2对于听觉毛细胞中的scramblase活性是必需的
Thibault Peineau,Irina Marcovich,Cristobal von Muhlenbrock Rodriguez et al.
Thibault Peineau et al.
Sensory transduction in auditory hair cells gates mechanosensitive ion channels, converting sound information into electrical signals (Zheng and Holt, 2021). Previously, we found that Transmembrane channel (TMC) proteins 1 and 2 form the po...