Effect of coupler tip size on round window stimulation with the floating mass transducer under controlled preload [0.03%]
不同耦合器尺寸的浮质量换能器在控制预载下对卵圆窗刺激的效果研究
Houguang Liu,Mohammad Ghoncheh,Daniel Schurzig et al.
Houguang Liu et al.
Objective: Mechanical stimulation of the cochlear round window (RW) extends the indication of active middle-ear implants to mixed and conductive hearing loss, yet outcomes vary considerably due to transducer-RW size misma...
Oren Poliva,Yuanxin Liu,Robert D Rafal
Oren Poliva
Background: The acoustic radiations connect the medial geniculate nucleus (MGN) of the thalamus with the auditory cortex in Heschl's gyrus (HG). Classic histological dissections described a trajectory that courses through...
Psychoacoustic and cognitive predictors of sound sensitivity in healthy young adults [0.03%]
健康青年人对声音敏感性的心理声学和认知预测因素
Breann Krygsman,Alisa Pitre,Sebastien Paquette
Breann Krygsman
Hyperacusis and sound sensitivity are complex phenomena influenced by both auditory and psychological factors. This study investigated the relationship between hearing thresholds, perceptual ratings of natural sounds, attitudes toward noise...
Berberrubine protects against noise-induced cochlear damage and hearing loss by inhibiting the p38 MAPK signaling pathway [0.03%]
伯柏鲁滨通过抑制p38丝裂原活化蛋白激酶信号通路对抗噪声性耳蜗损伤和听力损失
Hanbo Seng,Guodong Hong,Le Wang et al.
Hanbo Seng et al.
Cochlear hair cells are critical sensory receptors for auditory function, and exposure to high-intensity noise can lead to irreversible hearing loss. However, the mechanisms underlying noise-induced hearing loss (NIHL) are poorly understood...
Differences in hearing across the lifespan in two strains of Alzheimer's mouse models as measured using behavioral and physiological techniques [0.03%]
行为和生理技术在两种阿尔茨海默病小鼠模型生命期各个阶段的听力差异研究
Payton E Charlton,Kali Burke,Sevda Abdavinejad et al.
Payton E Charlton et al.
Alzheimer's disease (AD) is a brain condition with heterogeneity in disease progression due to genetic and environmental variables. There is a critical need to better understand the relationship of AD pathologies and potential modifiable fa...
Using vocoders to the implanted ear to investigate the binaural benefit for music sound quality in single-sided deaf cochlear implant users [0.03%]
利用声码器探究单侧耳植入用户音乐声音质量的双耳效益
Sean Lang,John J Galvin rd,Isaac Cooley et al.
Sean Lang et al.
Despite the poor sound quality provided by cochlear implants (CIs), single-sided deaf (SSD) CI users prefer to listen to music with the acoustic hearing (AH) and CI ears together rather than with the AH ear alone. The source of this binaura...
Vestibular habituation is associated with distinct autonomic signatures and greater reduction in visually induced motion sickness: A randomized controlled trial [0.03%]
前庭习惯化与视觉诱发运动病减轻相关的自主神经特征:一项随机对照试验
Qikun Zhang,Xinyang Chen,Chuanxia Cao et al.
Qikun Zhang et al.
This study compared the efficacy of short-duration, high-intensity versus stepwise, progressively lengthened optokinetic drum-chair training in alleviating visually induced motion sickness (VIMS) and modulating autonomic function. Ninety-si...
Circuit architecture and axonal branching in the efferent auditory system [0.03%]
听觉传出系统的电路结构和轴突分支现象
Brett R Schofield
Brett R Schofield
The auditory efferent system has been implicated in nearly all aspects of hearing, including adaptations to aging and response to damage or disease. The system encompasses a collection of descending neural pathways that are widespread, supp...
A porcine congenital deafness model with unconditional knockout of GJB2 generated by CRISPR/Cas9 genomic editing [0.03%]
利用CRISPR/Cas9基因组编辑技术制备无条件型GJB2敲除猪先天性耳聋模型
Fei Xie 谢飞,Xiaozhou Liu 刘晓宙,Lulu Wang 王露露 et al.
Fei Xie 谢飞 et al.
GJB2, the primary gene responsible for DFNB1, the most prevalent non-syndromic hearing loss (NSHL), has variants that account for over 50% of all prelingual hearing loss (HL). Mice are the main model for congenital hearing loss (CHL) resear...
Bayesian simulation of hearing thresholds at conventional and extended high frequencies in young adults [0.03%]
年轻人常规和扩展高频听阈的贝叶斯模拟
N Shahnaz,V Ciocca
N Shahnaz
The goal of this study was to characterize the population-level distributions of hearing thresholds at conventional and extended high frequencies (EHFs). To achieve this goal, distributions of typical hearing thresholds expressed in dB SPL ...