Trophoblast: The central unit of fetal growth, protection and programming [0.03%]
滋养层细胞：胎儿生长、保护和程序设定的中心单元
Frantisek Staud,Rona Karahoda
Frantisek Staud
The placenta is the first organ to be created during mammalian development. As the main link between the mother and the fetus it has more diverse functions than any other organ, serving as a digestive, excretory, respiratory, endocrine, and...
Current report of natural product development against breast cancer stem cells [0.03%]
当前天然产物乳腺癌干细胞研发进展报告
Adam Hermawan,Herwandhani Putri
Adam Hermawan
Chemotherapeutic agents are commonly used as neoadjuvant for breast cancer therapy. However, there is evidence of treatment failure for most of patients due to acquired resistance. Cancer stem cells, a small population of cells within tumor...
Snake venom components in medicine: From the symbolic rod of Asclepius to tangible medical research and application [0.03%]
蛇毒成分在医药中的应用：从医学象征的阿斯克勒庇俄斯杖到切实的医学研究和实践
Maria-Inacia Estevão-Costa,Raquel Sanz-Soler,Benjamin Johanningmeier et al.
Maria-Inacia Estevão-Costa et al.
Both mythologically and logically, snakes have always fascinated man. Snakes have attracted both awe and fear not only because of the elegant movement of their limbless bodies, but also because of the potency of their deadly venoms. Practic...
Knockdown of LncRNA MALAT1 contributes to cell apoptosis via regulating NF-κB/CD80 axis in neonatal respiratory distress syndrome [0.03%]
长链非编码RNA-MALAT1敲低通过调节NF-κB/CD80轴促进新生儿呼吸窘迫综合征细胞凋亡
Chenxia Juan,Qian Wang,Yan Mao et al.
Chenxia Juan et al.
Neonatal respiratory distress syndrome (NRDS) is a leading cause of morbidity in premature newborns and is a common reason for admission to the neonatal intensive care unit (NICU). Recent studies found that the pathogenesis of NRDS is not s...
Biosynthesized silver nanoparticles: Decoding their mechanism of action in Staphylococcus aureus and Escherichia coli [0.03%]
生物合成的银纳米颗粒：解码其在金黄色葡萄球菌和大肠杆菌中的作用机制
Melisa A Quinteros,Cano Aristizabal Viviana,Renné Onnainty et al.
Melisa A Quinteros et al.
The oxidative stress generation in bacteria by the presence of antibiotics (in this case silver nanoparticles (AgNPs)) is already widely known. Previously, we demonstrated that AgNPs generate oxidative stress in Staphylococcus aureus and Es...
A MAPK/c-Jun-mediated switch regulates the initial adaptive and cell death responses to mitochondrial damage in a neuronal cell model [0.03%]
一种MAPK/c-Jun介导的调控机制调节了神经元细胞模型中线粒体损伤后的初始适应性和细胞死亡反应
Thomas A Ryan,Katherine M Roper,Jacquelyn Bond et al.
Thomas A Ryan et al.
Parkinson's disease (PD) is defined by the progressive loss of dopaminergic neurons. Mitochondrial dysfunction and oxidative stress are associated with PD although it is not fully understood how neurons respond to these stresses. How adapti...
Human β-defensin 1 update: Potential clinical applications of the restless warrior [0.03%]
人类β-防御素1最新研究进展：不安分的战士——不尽的临床遐想与展望
Ángel H Álvarez,Moisés Martínez Velázquez,Ernesto Prado Montes de Oca
Ángel H Álvarez
Human β-defensin 1 (hBD-1) is a multifaceted antimicrobial peptide being a tumour suppressor and, depending on call of duty, capable of inducing self-nets and neutrophil extracellular traps (NETs) to capture and/or kill bacteria, participa...
Integrative analysis identified mediation effects of lncRNAs on the correlations between methylation and mRNA [0.03%]
整合分析鉴定出lncRNA在DNA甲基化与mRNA相关性中的中介效应
Xing-Bo Mo,Long-Fei Wu,Xiao-Ming Cai et al.
Xing-Bo Mo et al.
The aim of this study was to construct DNA methylation-lncRNA-mRNA interaction trios in peripheral blood mononuclear cells. We first conducted eQTL analyses using genome-wide methylation, lncRNA and mRNA expression data from 43 Chinese fema...
Erratum to "NDRG1 disruption alleviates cisplatin/sodiumlycididazole-induced DNA damage response and apoptosis in ERCC1-defective lung cancer cells" [Int. J. Biochem. Cell Biol. 100 (2018) 54-64] [0.03%]
“NDRG1缺失可缓解ERCC1缺陷的肺癌细胞中顺铂/氯尼达唑诱导的DNA损伤反应和凋亡”[Int. J. Biochem. Cell Biol. 100 (2018) 54-64]一文的勘误公告
Lang He,Kang Liu,Xiaoshan Wang et al.
Lang He et al.
Inhibition of Lincpint expression affects insulin secretion and apoptosis in mouse pancreatic β cells [0.03%]
Lincpint表达抑制影响小鼠胰岛β细胞的胰岛素分泌和凋亡
Yanan Zhu,Yihui Li,Chengting Dai et al.
Yanan Zhu et al.
LncRNAs have been reported to maintain islet function and are associated with the development of diabetes. Here, we investigated Lincpint biological functions in mouse pancreatic β cells both in vivo and in vitro. We observed that Lincpint...