RNA-binding proteins RBM20 and PTBP1 regulate the alternative splicing of FHOD3 [0.03%]
RNA结合蛋白RBM20和PTBP1调控FHOD3的可变剪接
P Lorenzi,A Sangalli,S Fochi et al.
P Lorenzi et al.
Regulation of alternative splicing events is an essential step required for the expression of functional cytoskeleton and sarcomere proteins in cardiomyocytes. About 3% of idiopathic dilated cardiomyopathy cases present mutations in the RNA...
Corrigendum to "P-3F, a microtubule polymerization inhibitor enhances P53 stability through the change in localization of RPS27a" [Int. J. Biochem. Cell Biol. 92 (2017) 53-62] [0.03%]
“P-3F，一种微管聚合抑制剂通过RPS27A定位的改变来增强P53稳定性》一文中图4b中蛋白标识的勘误[Int.J.Biochem.Cell Biol.92(2017)53-62]
Huai Wang,Jiang Feng,Tong Zhou et al.
Huai Wang et al.
Direct conversion of mouse embryonic fibroblast to osteoblast cells using hLMP-3 with Yamanaka factors [0.03%]
在Yamanaka转录因子的作用下利用hLMP-3直接将鼠胚胎成纤维细胞转分化为成骨细胞
Mahmoud F Ahmed,Ahmed Kamel El-Sayed,Hao Chen et al.
Mahmoud F Ahmed et al.
Large bone defects and bone loss after fractures remain significant challenges for orthopedic surgeons. Our study aims to find an available, applicable and biological treatment for bone regeneration overcoming the limitations in ESC/iPSC te...
Inhibition of HSP90β by ganetespib blocks the microglial signalling of evoked pro-inflammatory responses to heat shock [0.03%]
HSP90β抑制剂Ganetespib阻断小胶质细胞热休克诱导的促炎信号转导
Gen-Lin He,Zhen Luo,Ting-Ting Shen et al.
Gen-Lin He et al.
Although microglial reaction to heat shock is considered to be protective, heat shock is still a potential hazard caused by high temperatures. Recent studies indicate that the inhibition of the 90-kDa heat shock protein (HSP90) increasing t...
Hesam Movassagh,Latifa Koussih,Lianyu Shan et al.
Hesam Movassagh et al.
Semaphorins were originally discovered as essential mediators involved in regulation of axonal growth during development of the nervous system. Ubiquitously expressed on various organs, they control several cellular functions by regulating ...
Impact of p38γ mitogen-activated protein kinase (MAPK) on MDA-MB-231 breast cancer cells using metabolomic approach [0.03%]
利用代谢组学方法研究p38γ丝裂原活化蛋白激酶(MAPK)对MDA-MB-231乳腺癌细胞的影响
Hongshen Chen,Xin Wang,Fangdong Guo et al.
Hongshen Chen et al.
Background: The expression of p38 MAPK is high in breast cancer while its subunit p38γ had been rarely reported. We aimed to explain the effect of p38γ in breast cancer from the perspective of metabolomics. ...
Ahmed A Raslan,Jeong Kyo Yoon
Ahmed A Raslan
R-spondins (RSPOs) are secreted cysteine-rich glycoproteins that belong to a superfamily of thrombospondin type 1 repeat-containing proteins. RSPOs together with WNT proteins potentiate canonical WNT/β-catenin signaling activity. Over the ...
CD133 as a regulator of cancer metastasis through the cancer stem cells [0.03%]
通过癌症干细胞调控肿瘤转移的分子CD133
Geou-Yarh Liou
Geou-Yarh Liou
Cancer stem cells are the cancer cells that have abilities to self-renew, differentiate into defined progenies, and initiate and maintain tumor growth. They also contribute to cancer metastasis and therapeutic resistance, both of which are ...
miR-19b-3p integrates Jak-Stat signaling pathway through Plzf to regulate self-renewal in dairy goat male germline stem cells [0.03%]
Plzf介导的miR-19b-3p整合Jak-Stat信号通路调控山羊雄性生殖干细胞自我更新
Daguia Zambe John Clotaire,Xiaomin Du,Yudong Wei et al.
Daguia Zambe John Clotaire et al.
Jak-Stat pathway is the first pathway identified to stimulate spermatogonial stem cells (SSCs) self-renewal and maintenance activity. Recent studies have showed that stat3 a crucial gene implicated in this pathway can regulate self-renewal ...
Bactericidal action of Tat (47-58) peptide via attenuation of cell defense systems [0.03%]
tat(47-58)肽通过削弱细胞防御系统产生杀菌作用
JiEun Yun,Dong Gun Lee
JiEun Yun
Cells contain a variety of proteins, including those forming a cellular defense system against oxidative stress and DNA damage. In this study, we examined the antibacterial effect of Tat (47-58) peptide, a cell-penetrating peptide, derived ...