Relationship between estrogen and body composition, energy, and endocrine factors in obese women with normal and low REE [0.03%]
雌激素与肥胖妇女正常和低静息能量消耗值之间的关系
Somaye Ahmadi,Mohammad Reza Eshraghian,Mehdi Hedayati et al.
Somaye Ahmadi et al.
Objective: The aim of this study was to investigate the relationship between estrogen and leptin, thyroid (T3), Uncoupling Protein2 (UCP2), sex hormone binding globulin (SHBG), and resting energy expenditure(REE) in obese...
Sex differences in sleep apnea and comorbid neurodegenerative diseases [0.03%]
睡眠呼吸暂停及共病神经退行性疾病的性别差异研究进展
Brina Snyder,Rebecca L Cunningham
Brina Snyder
Sleep apnea is a disorder, which increasingly affects people worldwide. Whether the associated hypoxic events during sleep are central or obstructive in origin, the end result is excessive daytime sleepiness and an increased risk for severa...
Spironolactone voltammetric determination on renewable amalgam film electrode [0.03%]
可更新汞膜电极上螺内酯的伏安测定法研究
Joanna Smajdor,Robert Piech,Beata Paczosa-Bator
Joanna Smajdor
In this study a new high sensitive method of spironolactone (SP) determination is proposed using voltammetric technique. As the working electrode amalgam film silver based electrode (Hg(Ag)FE) was applied, that resulted in obtaining low lim...
Three steroid-binding globulins, their localization in the brain and nose, and what they might be doing there [0.03%]
三种类固醇结合球蛋白在脑和鼻腔中的定位及其可能的作用
J D Caldwell,K Londe,S D Ochs et al.
J D Caldwell et al.
Steroid-binding globulins (SBGs) such as sex hormone binding globulin, corticosteroid binding globulin, and vitamin-D binding protein are receiving increasing notice as being actively involved in steroid actions. This paper reviews data of ...
Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse [0.03%]
SOAT2功能丧失对溶酶体酸性脂酶缺陷型小鼠疾病进展的影响
Adam M Lopez,Jen-Chieh Chuang,Stephen D Turley
Adam M Lopez
Although only a small proportion of cholesterol in the body is esterified, in several diseases marked expansion of the esterified cholesterol (EC) pool occurs. These include Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD) w...
Membrane-initiated nuclear trafficking of the glucocorticoid receptor in hypothalamic neurons [0.03%]
下丘脑神经元中糖皮质激素受体的膜启动核转运现象
Jennifer R Rainville,Grant L Weiss,Nathan Evanson et al.
Jennifer R Rainville et al.
Glucocorticoid binding to the intracellular glucocorticoid receptor (GR) stimulates the translocation of the GR from the cytosol to the nucleus, which leads to the transactivation or transrepression of gene transcription. However, multiple ...
Regulation of extracellular matrix vesicles via rapid responses to steroid hormones during endochondral bone formation [0.03%]
软骨内骨骼形成过程中类固醇激素快速反应调控外基质囊泡生成
Niels Asmussen,Zhao Lin,Michael J McClure et al.
Niels Asmussen et al.
Endochondral bone formation is a precise and highly ordered process whose exact regulatory framework is still being elucidated. Multiple regulatory pathways are known to be involved. In some cases, regulation impacts gene expression, result...
Identification of d-seco modified steroid derivatives with affinity for estrogen receptor α and β isoforms using a non-transcriptional fluorescent cell assay in yeast [0.03%]
利用酵母中非转录荧光细胞测定法定量识别雌激素受体α和β同工型具有亲和力的d-secosteroid衍生物
Sofija S Bekić,Maja A Marinović,Edward T Petri et al.
Sofija S Bekić et al.
Synthesis and biological evaluation of steroidal derivatives with anticancer properties is an active area of drug discovery. Here we measured the relative affinities of d-seco modified steroidal derivatives for estrogen receptor α, estroge...
Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp. SCSIO41007 [0.03%]
来自海洋海绵相关真菌Cladosporium sp. SCSIO41007的三个高氧甾醇和一个二氢异香豆素类新化合物
Xiaoyan Pang,Xiuping Lin,Junfeng Wang et al.
Xiaoyan Pang et al.
Three new highly oxygenated sterols (1-3) and a new dihydroisocoumarin (7) together with six known compounds were isolated from the extracts of the culture of a sponge-derived fungus Cladosporium sp. SCSIO41007. The structures of all new co...
Clinical utility of an ultrasensitive late night salivary cortisol assay by tandem mass spectrometry [0.03%]
用于评估儿童和成人下丘脑-垂体-肾上腺轴功能的超高灵敏度唾液皮质醇检测方法的价值
Lillian R Sturmer,Dylan Dodd,Christina S Chao et al.
Lillian R Sturmer et al.
Background: Late night salivary cortisol measurement is a clinically important and convenient screening test for Cushing's syndrome. Tandem mass spectrometry (LC-MS/MS) assays have superior sensitivity and specificity com...