Nandrolone combined with strenuous resistance training reduces vascular nitric oxide bioavailability and impairs endothelium-dependent vasodilation [0.03%]
睾内酯联合剧烈抗阻训练降低血管一氧化氮生物利用度并损害内皮依赖性血管扩张功能
Vinicius Guzzoni,Tatiana Sousa Cunha,Vander José das Neves et al.
Vinicius Guzzoni et al.
Anabolic Androgenic Steroids (AASs) misuse has increased among adolescents and recreational athletes due to their potential effects on muscle hypertrophy. On the other hand, AAS might induce alterations on cardiovascular system, although so...
Cristel V Camacho,Ramesh Choudhari,Shrikanth S Gadad
Cristel V Camacho
Long noncoding RNAs (lncRNAs) are implicated in several biological processes, including but not limited to cardiovascular physiology, reproduction, differentiation, metabolism, DNA repair, and inflammation. Under normal physiological condit...
Revisiting progesterone receptor (PR) actions in breast cancer: Insights into PR repressive functions [0.03%]
重新审视乳腺癌中孕激素受体（PR）的作用：探讨PR的抑制功能的见解
Cecilia J Proietti,Mauro E Cenciarini,Patricia V Elizalde
Cecilia J Proietti
Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls developmental processes and proliferation and differentiation during the reproductive cycle and pregnancy. PR also plays a role in progression of ...
Development of leads targeting ER-α in breast cancer: An in silico exploration from natural domain [0.03%]
针对乳腺癌ER-α靶点的先导物研发：来自天然域的模拟探索
Snehal S Ashtekar,Neela M Bhatia,Manish S Bhatia
Snehal S Ashtekar
The steroid, estrogen has been recognized as being important for stimulating the growth of breast cancers primarily mediated via the steroidal estrogen receptor-α (ER-α). Inhibition of estrogen activity by small molecules with increased t...
Yasmin M Vasquez
Yasmin M Vasquez
Estrogen (E2) plays a central role in the developmental, metabolic and reproductive functions of both males and females. E2 acts via the estrogen receptor alpha (ERα) to regulate the transcription of genes involved in numerous cellular fun...
Mavis A Tenkorang,Brina Snyder,Rebecca L Cunningham
Mavis A Tenkorang
Oxidative stress has been implicated in a number of neurodegenerative diseases spanning various fields of research. Reactive oxygen species can be beneficial or harmful, depending on their concentration. High levels of reactive oxygen speci...
Doping control analysis of 13 steroids and structural-like analytes in human urine using Quadrupole-Orbitrap LC-MS/MS with parallel reaction monitoring (PRM) mode [0.03%]
采用平行反应监测（PRM）模式的四极杆-轨道阱液质联用技术测定人尿中13种类固醇及其结构类似物 doping control analysis of 13 steroids and structural-like analytes in human urine using quadrupole-orbitrap lc-ms/ms with parallel reaction monitoring (prM) mode
Genye He,Yun Wu,Jianghai Lu
Genye He
Anabolic androgenic steroids (AASs) and structural-like substances are commonly prohibited substances found in doping control studies that can be difficult to accurately detect. In the present study, 11 AASs and 2 structural-like substances...
Estradiol receptor profile and estrogen responsiveness in laryngeal cancer and clinical outcomes [0.03%]
雌二醇受体谱型与喉癌的雌激素敏感性及其临床预后的相关性研究
Nofrat Schwartz,Anjali Verma,Chandana Muktipaty et al.
Nofrat Schwartz et al.
There is growing evidence that laryngeal cancers are responsive to sex hormones, specifically 17β-estradiol (E2), despite controversy regarding the presence and characterization of E2 receptors (ER). Determination of sex hormone responsive...
Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13] [0.03%]
“雌激素受体α、β和芳香化酶在非小细胞肺癌中的预后价值的研究勘误[类固醇113（2016）5-13]”
Kaja Skjefstad,Thea Grindstad,Mehrdad Rakaee Khanehkenari et al.
Kaja Skjefstad et al.
Published Erratum
Steroids. 2018 Feb:130:36-37. DOI:10.1016/j.steroids.2017.11.010 2018
Enlarged adipocytes in subcutaneous adipose tissue associated to hyperandrogenism and visceral adipose tissue volume in women with polycystic ovary syndrome [0.03%]
多囊卵巢综合征女性皮下脂肪组织中与高雄激素和内脏脂肪量相关的增大的脂肪细胞
Bárbara Echiburú,Francisco Pérez-Bravo,José E Galgani et al.
Bárbara Echiburú et al.
Context: Polycystic ovary syndrome (PCOS) is an androgen excess disorder associated with obesity and adipose tissue disturbances. Our aim was to evaluate gene expression of adipocytokines and adipocyte characteristics in ...