Role of the ERp57 protein (1,25D3-MARRS receptor) in murine mammary gland growth and development [0.03%]
ERp57蛋白（1,25D3-MARRS受体）在小鼠乳腺生长发育中的作用
Allison M Wilkin,Amber Harnett,Michael Underschultz et al.
Allison M Wilkin et al.
The protein disulfide isomerase ERp57 (GRp58/PDIA3/1,25D3-MARRS) has been implicated in a multitude of signaling pathways throughout the entire body. Most thoroughly studied for its protein-folding role, ERp57 has also been found to have mu...
Effects of stanozolol on apoptosis mechanisms and oxidative stress in rat cardiac tissue [0.03%]
斯坦唑醇对大鼠心脏组织凋亡机制及氧化应激的影响
Mehtap Kara,Eren Ozcagli,Tuğba Kotil et al.
Mehtap Kara et al.
Stanozolol is a widely used 17α-alkylated anabolic androgenic steroid (AAS) derivative. Despite stanozolol's adverse effects, its effect on oxidative stress parameters and mitochondrial apoptosis pathway is not clearly defined. In our stud...
Androst-5-ene-3β,7α/β,17β-triols, their plasma levels and dependence on the hypothalamic-pituitary-adrenal axis [0.03%]
雄甾-5-烯-3β,7α/β,17β-三醇、其血浆水平及其对下丘脑 - 垂体 - 肾上腺轴的依赖性
Luboslav Stárka,Martin Hill,Lucie Kolatorova et al.
Luboslav Stárka et al.
Androst-5-ene-triols are metabolites of dehydroepiandrosterone, the most abundant steroid hormone in human circulation. Many observations in rodents have demonstrated the anti-inflammatory and immune modulating activity of 7β-hydroxy-andro...
Synthesis and biological evaluation of estrone 3-O-ether derivatives containing the piperazine moiety [0.03%]
含哌嗪类化合物的雌酮3-O醚衍生物的合成及生物活性评价
Hong Chen,Xue Liang,Tao Sun et al.
Hong Chen et al.
A series of new estrone derivatives were designed and synthesized, and their structures were confirmed by spectroscopic methods. All new estrone derivatives were investigated for their in vitro cytotoxic efficacies against a panel of three ...
Comparative investigation of binding interactions with three steroidal derivatives of d(GGGT)4 G-quadruplex aptamer [0.03%]
三种类固醇衍生物与d(GGGT)4G-四链体适配子结合相互作用的比较研究
Shan Huang,Yu Liang,Jianguo Cui et al.
Shan Huang et al.
Steroidal derivatives have attracted tremendous attentions in biological and biomedical areas, due to their variety biological activities. The investigation of structural influences helps in understanding their biological activities. The in...
Comparative Study
Steroids. 2018 Apr:132:46-55. DOI:10.1016/j.steroids.2018.02.003 2018
Estrogen receptor-alpha isoforms are the main estrogen receptors expressed in non-small cell lung carcinoma [0.03%]
非小细胞肺癌中的雌激素受体-α主要表达形式为雌激素受体alpha异构体
Vasiliki Pelekanou,Eleftheria Anastasiou,Efstathia Bakogeorgou et al.
Vasiliki Pelekanou et al.
The expression profile of estrogen receptors (ER) in Non-Small Cell Lung Carcinoma (NSCLC) remains contradictory. Here we investigated protein and transcriptome expression of ERα wild type and variants. Tissue Micro-Arrays of 200 cases of ...
New product identification in the sterol metabolism by an industrial strain Mycobacterium neoaurum NRRL B-3805 [0.03%]
由产工业菌株瘤胃分枝杆菌新 aurum NRRL B-3805 识别的新产品在固醇代谢中的作用
Xuemei Li,Xi Chen,Yu Wang et al.
Xuemei Li et al.
Mycobacterium neoaurum NRRL B-3805 metabolizes sterols to produce androst-4-en-3,17-dione (AD) as the main product, and androsta-1,4-dien-3,17-dione, 9α-hydroxy androst-4-en-3,17-dione and 22-hydroxy-23,24-bisnorchol-4-en-3-one have been i...
Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2 [0.03%]
黄酮类和异黄酮类化合物抑制人及大鼠11β-羟基类固醇脱氢酶同工酶1和2的活性比较研究
Qiqi Zhu,Fei Ge,Yaoyao Dong et al.
Qiqi Zhu et al.
Many flavonoids and isoflavonoids have anti-diabetic effects in animal models. However, the mechanisms that are involved are generally unclear. Since 11β-hydroxysteroid dehydrogenases (HSD11Bs) play important roles in diabetes, we hypothes...
Comparative Study
Steroids. 2018 Apr:132:25-32. DOI:10.1016/j.steroids.2018.01.013 2018
Cholesterol internalization and metabolism in insect prothoracic gland, a steroidogenic organ, via lipoproteins [0.03%]
昆虫前胸腺中通过脂蛋白介导的胆固醇内吞及代谢的研究
Fumihiko Igarashi,Mari H Ogihara,Masatoshi Iga et al.
Fumihiko Igarashi et al.
Dietary sterols including cholesterol and phytosterols are essential substrates for insect steroid hormone (ecdysteroid) synthesis in the prothoracic glands (PGs). In the silkworm Bombyx mori, one of the model species of insects, the steroi...
Extraction optimization and UHPLC method development for determination of the 20-hydroxyecdysone in Sida tuberculata leaves [0.03%]
Sida tuberculata叶中20-羟蜕皮酮的提取优化及UHPLC测定方法开发
Hemerson S da Rosa,Mariana Koetz,Marí Castro Santos et al.
Hemerson S da Rosa et al.
Sida tuberculata (ST) is a Malvaceae species widely distributed in Southern Brazil. In traditional medicine, ST has been employed as hypoglycemic, hypocholesterolemic, anti-inflammatory and antimicrobial. Additionally, this species is chemi...