Urinary steroid profiling by gas chromatography mass spectrometry: Early features of malignancy in patients with adrenal incidentalomas [0.03%]
气相色谱-质谱法尿甾体分析在肾上腺意外瘤患者中的应用：恶性肿瘤的早期特征
Z R Shafigullina,L I Velikanova,N V Vorokhobina et al.
Z R Shafigullina et al.
Previously undisclosed bioactive sterols from corbiculid bivalve clam Villorita cyprinoides with anti-inflammatory and antioxidant potentials [0.03%]
一种具有抗炎和抗氧化潜力的半游泳蛤（Villorita cyprinoides）中未被披露过的生物活性固醇类成分
Minju Joy,Kajal Chakraborty
Minju Joy
The estuarine Corbiculid bivalve black clam, Villorita cyprinoides collected from the Southwestern coastline regions of Arabian Sea are significant resources of nutritional and bioactive pluralities. The purification of ethyl acetate:methan...
Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis [0.03%]
环阿尔泰宁型皂苷元衍生物通过抑制NFκB活化作为化学预防策略来抑制炎症诱导的前列腺癌发生发展
Bilge Debeleç-Bütüner,Mert Burak Öztürk,Özgür Tağ et al.
Bilge Debeleç-Bütüner et al.
Chronic inflammation is associated to 25% of cancer cases according to epidemiological data. Therefore, inhibition of inflammation-induced carcinogenesis can be an efficient therapeutic approach for cancer chemoprevention in drug developmen...
Possible mechanisms underlying fatty liver in a rat model of male hypogonadism: A protective role for testosterone [0.03%]
雄性生殖功能低下的脂肪肝可能机制及其保护作用睾酮的作用研究
Hussein F Sakr,Abdelaziz M Hussein,Elsayed A Eid et al.
Hussein F Sakr et al.
Aims: To investigate the effects of testosterone (Test) deficiency and testosterone replacement therapy (TRT) on the development of non-alcoholic fatty liver disease (NAFLD) and associated peripheral insulin resistance (I...
Facile one-pot multicomponent synthesis and molecular docking studies of steroidal oxazole/thiazole derivatives with effective antimicrobial, antibiofilm and hemolytic properties [0.03%]
一种简便的一锅多组分合成具有有效抗菌、抗生物膜和溶血性能的甾体噁唑/噻唑衍生物及其分子对接研究
Anam Ansari,Abad Ali,Mohd Asif et al.
Anam Ansari et al.
A series of steroidal oxazole and thiazole derivatives have been synthesized employing thiosemicarbazide/semicarbazide hydrochloride and ethyl 2-chloroacetoacetate with a simple and facile one-pot multicomponent reaction pathway. The antimi...
Adrenal androgen measurement for assessing the selectivity of adrenal venous sampling in primary aldosteronism [0.03%]
肾上腺静脉取样的选择性测定原发性醛固酮增多症患者肾上腺雄激素水平的效果
Hongyun Li,Xuebin Zhang,Shanmei Shen et al.
Hongyun Li et al.
Adrenal venous sampling (AVS) is the reference standard for primary aldosteronism (PA) subtyping. Cortisol is widely used to assess the success of selective AVS, but it is not always reliable. The aim of the present study was to investigate...
A comparative review on estrogen receptors in the reproductive male tract of non mammalian vertebrates [0.03%]
非哺乳动物雌激素受体生殖道的研究进展及展望
Mariailaria Verderame,Rosaria Scudiero
Mariailaria Verderame
Estrogen receptors alpha (ERα) and beta (ERβ) are transcription factors known to be involved in the regulation of many complex physiological processes in mammals. They are expressed primarily in the reproductive tract of all vertebrates f...
Phytoestrogens and mycoestrogens interacting with breast cancer proteins [0.03%]
植物雌激素和真菌雌激素与乳腺癌蛋白的相互作用
Diana Montes-Grajales,Esperanza Martínez-Romero,Jesus Olivero-Verbel
Diana Montes-Grajales
Breast cancer is a highly heterogeneous disease influenced by the hormonal microenvironment and the most common malignancy in women worldwide. Some phytoestrogens and mycoestrogens have been epidemiologically linked as risk factors or prote...
Anticancer activity of novel steroidal 6-substituted 4-en-3-one D-seco dinitriles [0.03%]
新型甾族6位取代的4烯-3酮D半乳糖甘露聚糖二腈的抗肿瘤活性
Andrea R Nikolić,Ivana Z Kuzminac,Suzana S Jovanović-Šanta et al.
Andrea R Nikolić et al.
Steroidal 16,17-seco-16,17a-dinitriles possessing 4-ene-3,6-dione (3), 6-methylene-4-en-3-one (5), (6E)-hydroxyimino-4-en-3β-ol (9) or (6E)-hydroxyimino-4-en-3-one (10) moiety were synthesized starting from 3β-acetoxy-16,17-secoandrost-4-...
Hyfraxins A and B, cytotoxic ergostane-type steroid and lanostane triterpenoid glycosides from the invasive ash dieback ascomycete Hymenoscyphus fraxineus [0.03%]
来源于入侵白蜡树枯死座囊菌Hymenoscyphus fraxineus的细胞毒性麦角甾醇型固醇和 lanostane三萜糖苷hyfraxins A 和 B
Frank Surup,Sandra Halecker,Manfred Nimtz et al.
Frank Surup et al.
A virulent culture of Hymenoscyphus fraxineus, the causal agent of ash dieback, was investigated for its production of secondary metabolites in a 70 L batch fermentation. Chemical analysis of the mycelial extract by means of flash chromatog...