High expression of TIM-3 and KIM-1 in blood and urine of renal allograft rejection patients [0.03%]
肾移植排斥反应患者血液和尿液中TIM-3和KIM-1的高表达
Sanaz Keshavarz Shahbaz,Fatemeh Pourrezagholi,Mehri Barabadi et al.
Sanaz Keshavarz Shahbaz et al.
Background: T cell immunoglobulin and mucin domain 3 (TIM-3) is involved in alloimmune and autoimmune responses, as well as tolerance induction in kidney transplantation. Kidney injury molecule-1 (KIM-1) is highly express...
Comparative Study
Transplant immunology. 2017 Aug:43-44:11-20. DOI:10.1016/j.trim.2017.07.002 2017
Low utility of serum 25-hydroxyvitamin D3 and 1, 25-dihydroxyvitamin D3 in predicting peripheral Treg and Th17 cell counts in ESRD and renal transplant patients [0.03%]
血清25-羟基维生素D3和1, 25-二羟基维生素D3不能用于预测ESRD及肾移植患者外周Treg细胞和Th17细胞数量
Mostafa G Aly,Li Zhu,Rolf Weimer et al.
Mostafa G Aly et al.
Background: Vitamin D has shown an immune-modulatory effect in different studies. Vitamin D stimulates Tregs and inhibits Th17 cells. The immune-modulatory role of vitamin D in chronic kidney disease (CKD) and renal trans...
Clinical Trial
Transplant immunology. 2017 Aug:43-44:3-10. DOI:10.1016/j.trim.2017.07.003 2017
Time-course of plasma inflammatory mediators in a rat model of brain death [0.03%]
脑死亡大鼠模型血浆炎性介质的时间过程学研究
Majid Esmaeilzadeh,Mahmoud Sadeghi,Roland Galmbacher et al.
Majid Esmaeilzadeh et al.
Background: Brain death (BD) is a donor-associated risk factor that negatively affects transplantation outcome. The inflammation associated with BD appears to have a negative effect on organ quality. Complement activation...
Associations between acute GVHD-related biomarkers and endothelial cell activation after allogeneic hematopoietic stem cell transplantation [0.03%]
急性GVHD相关生物标志物与allo-HSCT后内皮细胞活化之间的关联
Shosaku Nomura,Kazuyoshi Ishii,Shinya Fujita et al.
Shosaku Nomura et al.
Background: Hematopoietic stem cell transplantation (HSCT) can cause serious transplant-related complications such as graft-versus-host disease (GVHD). Acute GVHD (aGVHD) has been diagnosed by clinical manifestations, lab...
Clinical Trial
Transplant immunology. 2017 Aug:43-44:27-32. DOI:10.1016/j.trim.2017.06.004 2017
Gionata Spagnoletti,Maria Paola Salerno,Rosaria Calia et al.
Gionata Spagnoletti et al.
Recent results reported by Ciancio et al. have demonstrated the long term successful use of dual induction therapy in kidney transplant recipients. Our experience using an "induction cocktail", thymoglobuline plus basiliximab, started in 20...
Cytokines affecting CD4+T regulatory cells in transplant tolerance. III. Interleukin-5 (IL-5) promotes survival of alloantigen-specific CD4+ T regulatory cells [0.03%]
影响CD4+T调节细胞的细胞因子与移植耐受III. IL-5促进抗原特异性CD4+T调节细胞的存活
Bruce M Hall,Karren M Plain,Giang T Tran et al.
Bruce M Hall et al.
CD4+T cells mediate antigen-specific allograft tolerance, but die in culture without activated lymphocyte derived cytokines. Supplementation of the media with cytokine rich supernatant, from ConA activated spleen cells, preserves the capaci...
mir-155 expression is downregulated in kidney transplant patients with human cytomegalovirus infection [0.03%]
人巨细胞病毒感染的肾移植患者中mir-155表达下调
Massimiliano Bergallo,Stefano Gambarino,Paola Montanari et al.
Massimiliano Bergallo et al.
MicroRNAs are small, noncoding RNAs that control expression of target genes through inhibiting protein translation or inducing degradation of mRNA transcripts of target genes. According to the latest update, 2578 unique mature miRNAs are cu...
Clinical Trial
Transplant immunology. 2017 Aug:43-44:60-63. DOI:10.1016/j.trim.2017.06.002 2017
Immunogenicity of Class I HLA but not preformed low MFI donor specific antibodies correlates with outcomes after first renal transplantation [0.03%]
术前供者特异性低强度I类HLA抗体而非预存高亲和力II类HLA抗体影响初次肾移植的临床结果
A Lobashevsky,W Goggins,K Rosner et al.
A Lobashevsky et al.
Background: The role of low levels of circulating donor specific antibodies (DSA) producing negative flow cytometry cross match is not completely defined. The purpose of this study was to examine the clinical significance...
Clinical Trial
Transplant immunology. 2017 Aug:43-44:42-48. DOI:10.1016/j.trim.2017.06.001 2017
A model of acute renal allograft rejection in outbred Yorkshire piglets [0.03%]
用于杜洛克猪let急性肾移植排斥的临床前模型研究
Randi Lassiter,Youli Wang,Xuexiu Fang et al.
Randi Lassiter et al.
Pigs represent a desirable animal model for the study of rejection in kidney transplantation with inbred Yucatan miniature swine (YMS) the most commonly studied strain due to well defined swine leukocyte antigen (SLA) genotypes. However, li...
The recipient CCR5 variation predicts survival outcomes after bone marrow transplantation [0.03%]
移植后生存期与CCR5受体多态性有关
Tomohiro Horio,Shohei Mizuno,Kaori Uchino et al.
Tomohiro Horio et al.
The chemokine receptor CCR5 plays roles in the trafficking of effector cells towards the site of inflammation. We retrospectively examined the impact of the CCR5 variation (rs1800023, -2086A>G) on transplant outcomes in a cohort of 329 pati...