Beyond biopsy and drug levels: Are TTV and dd-CFDNA the next frontiers in transplant monitoring? [0.03%]
超越活检和药物浓度监测:TTV和dd-CFDNA能否成为移植术后监测的新前沿?
Priya Sharma,Ankita Ahlawat
Priya Sharma
Emerging biomarkers are reshaping the landscape of post-transplant surveillance by offering non-invasive, biologically meaningful insights beyond traditional biopsy and drug-level monitoring. Torque Teno Virus (TTV), a ubiquitous, non-patho...
The impact of rabbit anti-thymocyte globulin (thymoglobulin) timing and dosing on pediatric stem cell transplantation outcomes: Time to move forward [0.03%]
兔抗胸腺细胞球蛋白(胸腺球蛋白)的时机和剂量对儿科干细胞移植结局的影响:是时候向前发展了
Mohammad Jahanpanah,Maryam Behfar,Hamid Farajifard et al.
Mohammad Jahanpanah et al.
Anti-thymocyte globulin (ATG) remains integral to graft-versus-host disease (GvHD) prophylaxis in allogeneic hematopoietic stem cell transplantation (HSCT), yet its optimal dosing is unresolved. Excessive immunosuppression can impair immune...
Nebulized mitochondrial transplantation attenuates inflammation and improves graft function in a murine donation after cardiac death lung transplant model [0.03%]
雾化线粒体移植减轻炎症并改善 Donation After Cardiac Death 肺移植小鼠模型的移植物功能
Logan Langerude,Dianna Nord,Alexander McQuiston et al.
Logan Langerude et al.
Background: Mitochondrial transplantation is a promising therapy for ischemia reperfusion injury (IRI), with efficacy demonstrated in preclinical and early clinical cardiac studies. Its application in lung transplantation...
CXCL9, CXCL11, and CXCR3 mRNA expression and protein level in blood and urine of kidney transplant rejected patients [0.03%]
肾移植排斥反应患者血液及尿液中CXCL9、CXCL11和CXCR3的mRNA表达量及蛋白水平的研究
Narges Akhgar,Afsoon Afshari,Ramin Yaghobi et al.
Narges Akhgar et al.
Background: CXCL9 and CXCL11 are chemokine ligands that bind to the CXCR3 receptor. Their interaction mediates the recruitment, activation, and differentiation of immune cells, including T helper 1 (Th1) cells, CD8+ cytot...
Belatacept in liver transplantation: Results of a national survey among French specialists [0.03%]
肝移植中的贝尔塔西普:法国专家全国调查结果
Jérôme Dumortier,Filomena Conti,Claire Francoz et al.
Jérôme Dumortier et al.
Background: Belatacept has been approved and widely used for around ten years to prevent acute rejection after kidney transplantation. Its use in liver transplantation (LT) remains anecdotal. The objective of this study w...
Human leukocyte antigens in the era of precision medicine in immunology [0.03%]
免疫学精确诊断时代的人类白细胞抗原研究进展
Baris Ulum,Gamze Sonmez,Deniz Cagdas
Baris Ulum
HLA molecules play a crucial role in immune reactivity, influencing autoimmune diseases, transplantation immunology, susceptibility to infectious diseases, drug hypersensitivity, and personalized medicine. Here, we highlight the transformat...
Chidamide maintenance after allogeneic hematopoietic stem cell transplantation in mycosis fungoides: A case report [0.03%]
异基因造血干细胞移植后用于蕈样真菌病维持治疗的希维达(case report)
JiaJuan Ji,Sen Qi,YuTing Zhu et al.
JiaJuan Ji et al.
Primary cutaneous T-cell lymphoma (CTCL) comprises a group of rare, aggressive non-Hodgkin lymphomas, of which mycosis fungoides (MF) and Sézary syndrome are the most common subtypes. In the absence of a universally accepted standard of ca...
Association of HLA alleles and mismatches with post-transplant lymphoproliferative disorder in solid organ transplant recipients: a systematic review and meta-analysis [0.03%]
人类白细胞抗原等位基因和实体器官移植受者移植物抗原不合与移植后淋巴增生性疾病的相关性:系统评价和meta分析
Sara Assadiasl,Mahdi Yazdani,Hanieh Mojtahedi et al.
Sara Assadiasl et al.
Background: Post-transplant lymphoproliferative disorder (PTLD) is a rare but significant complication after solid organ transplantation. Many factors, including viral infections and immunosuppressive drugs, have been sho...
Anti-BAFF treatment modulates intragraft fibrosis and DKK3 expression in a non-adherence model of experimental kidney transplantation [0.03%]
抗BAFF治疗调节非依从性实验肾移植模型中的移植物纤维化和DKK3表达
A Preiss,C Daniel,E Vonbrunn et al.
A Preiss et al.
Following kidney transplantation, rejection and the presence of interstitial fibrosis and tubular atrophy represent prognostically unfavorable factors and are associated with reduced graft survival. The B-cell activating factor (BAFF) and t...
An adaptive quantification scheme for profiling serum antibody level in transplant immunology [0.03%]
移植免疫学中的一种自适应量化方案,用于评估血清抗体水平
Thomas Schacker,Claudia Lehmann,Ramona Landgraf et al.
Thomas Schacker et al.
Luminex single antigen bead (SAB) assays are widely used in transplantation medicine for detecting HLA-specific antibodies, but the relative nature of the assay signal complicates interpretation and comparability. Also, applying fixed cutof...