Genome-wide association studies in kidney transplantation: Advantages and constraints [0.03%]
肾脏移植的全基因组关联研究：优势与局限性
Jianxin Yang,Frans H J Claas,Michael Eikmans
Jianxin Yang
Since the discovery of the human leukocyte antigen (HLA) system, the role of HLA molecules in the field of transplantation has been appreciated: better matching leads to better graft function. Since then, the association of other genetic po...
Changes of NK cell subsets with time post-transplant in peripheral blood of renal transplant recipients [0.03%]
肾移植受者外周血NK细胞亚群的动态变化
Li Zhu,Mostafa Aly,Haihao Wang et al.
Li Zhu et al.
Background: There is evidence that NK cells with low cytotoxicity but strong immunoregulatory characteristics contribute to good graft outcome. We attempted to investigate which NK cell subsets increase post-transplant an...
CMV seronegative donors: Effect on clinical severity of CMV infection and reconstitution of CMV-specific immunity [0.03%]
CMV阴性的供者：对CMV感染临床症状严重程度及CMV特异性免疫重建的影响
P L J van der Heiden,H M van Egmond,S A J Veld et al.
P L J van der Heiden et al.
Background: Cytomegalovirus (CMV)-specific T-cells are crucial to prevent CMV disease. CMV seropositive recipients transplanted with stem cells from a CMV seronegative allogeneic donor (R+D-) may be at risk for CMV diseas...
Genetic risk factors for post-transplantation diabetes mellitus in Chinese Han renal allograft recipients treated with tacrolimus [0.03%]
他克莫司诱导肾移植受者的遗传易感因素与移植物后糖尿病的关系研究
Xiaoming Zhang,Tongyi Men,Haitao Liu et al.
Xiaoming Zhang et al.
Background: Post-transplantation diabetes mellitus (PTDM) is a serious metabolic complication after kidney transplantation. The aim of this study was to explore the association of clinical variables and five selected sing...
Effects of different serotonin receptor subtype antagonists on the development of cardiac allograft vasculopathy in murine aortic allografts [0.03%]
不同型五羟色胺受体拮抗剂对小鼠主动脉移植物心脏移植物血管病发展的影响
Annika Gocht,Jörg H W Distler,Bernd Spriewald et al.
Annika Gocht et al.
Background: Cardiac allograft vasculopathy (CAV) is the main obstacle for long-term survival after heart transplantation. Alloimmune mediated chronic vascular rejection results in several mechanisms like platelet activati...
Immune modulation by silencing CD80 and CD86 production in dendritic cells using small hairpin RNA to reduce heart transplant rejection [0.03%]
用小型发卡RNA沉默树突状细胞中CD80和CD86产生以调节免疫系统从而减少心脏移植排斥反应
Zhiqiang Yang,Yujian Liu,Xiaolei Zhou
Zhiqiang Yang
RNA interference (RNAi) plays a potential role in organ transplantation. Small hairpin RNA (shRNA) is an artificial RNA molecule with a tight hairpin turn that can be used to silence the expression of a target gene. We constructed shRNA tar...
Complement-fixing donor-specific anti-HLA antibodies and kidney allograft failure [0.03%]
补体固定的供者特异性抗HLA抗体与肾移植失败的关系
Helena B Cazarote,Silvia Shimakura,Joana S Valdameri et al.
Helena B Cazarote et al.
Detection of donor-specific antibodies (DSA) has improved the risk classification and post-transplant evaluation of kidney recipients. Moreover, assessment of DSA C1q-binding ability has been shown to improve the individual risk classificat...
Gene expression profiling scores in dual organ transplant patients are similar to those in heart-only recipients [0.03%]
双重器官移植患者基因表达评分与单纯心脏移植受者类似
Sandra A Carey,Kristen M Tecson,Aayla K Jamil et al.
Sandra A Carey et al.
Background: Serial gene expression profiling (GEP) may reduce the need for endomyocardial biopsies for detecting acute cellular rejection (ACR) after transplantation, but its performance in dual organ transplant recipient...
Role for primary immunosuppression with everolimus after pulmonary transplantation [0.03%]
伊维莫司在肺移植后初始免疫抑制中的作用
J Salman,K Jansson,Th Siemeni et al.
J Salman et al.
Comparative analysis of two methods to detect donor-specific anti-HLA antibodies after kidney transplant [0.03%]
肾脏移植术后两种检测供者特异性抗HLA抗体方法的比较分析
Beatriz Chamun Gil,Adriane Stefani Silva Kulzer,Priscila de Moraes et al.
Beatriz Chamun Gil et al.
Preformed anti-human leukocyte antigen (HLA) antibodies may be present in the blood of kidney transplant candidates. The production of these antibodies may occur in the post-transplant period, with the possible development of donor-specific...
Comparative Study
Transplant immunology. 2018 Aug:49:7-11. DOI:10.1016/j.trim.2018.03.006 2018