Characterization of T cell immunophenotypes in intestinal transplantation: A pilot study [0.03%]
肠道移植中T细胞免疫表型的特征研究:一项初步研究
Marjorie-Anne R Guerra,Maura Rossetti,Zhenyu Zhang et al.
Marjorie-Anne R Guerra et al.
Immunophenotyping of peripheral blood mononuclear cells has been shown to be a useful, non-invasive method of predicting acute cellular rejection (ACR) following intestinal transplantation (ITx). Our objectives were to characterize differen...
Single center observation of the role of pre-existing HLA-DP antibodies in humoral rejection following renal transplantation [0.03%]
单中心观察供者特有HLA-DP抗体在肾移植后介导的免疫反应中的作用
A Nikaein,M Lerman,G Rofaiel et al.
A Nikaein et al.
HLA antigens, including HLA-A, B, C, DR and DQ have long been known to have an effect on transplant outcome. Presence of antibodies to these antigens is detrimental to transplant outcome as it ends up to either acute or chronic humoral reje...
Case Reports
Transplant immunology. 2018 Dec:51:58-61. DOI:10.1016/j.trim.2018.09.002 2018
Ankang Hu,Yan Wang,Honghua Yuan et al.
Ankang Hu et al.
Although immunosuppressive therapies have made organ transplantation a common medical procedure worldwide, chronic toxicity is a major issue of long-term treatment. One method to improve such therapies is the application of immunomodulatory...
Antibody-mediated rejection in the Banff classifications of 2007 and 2017: A comparison of renal graft loss prediction capability [0.03%]
2007和2017年Banff标准中抗体介导的排斥反应对肾移植失功预测能力的比较
David Solar-Cafaggi,Lluvia Marino,Norma Uribe-Uribe et al.
David Solar-Cafaggi et al.
Background: Antibody-mediated rejection (ABMR) is the leading cause of kidney graft loss worldwide. Criteria for acute humoral rejection (currently labeled active humoral rejection) established by the 2007 Banff classific...
Comparative Study
Transplant immunology. 2018 Dec:51:40-44. DOI:10.1016/j.trim.2018.08.008 2018
New DQA1 allele specific antibody against epitope 2D (an exon 1 encoded amino acid). Considerations for alleles under the same P-group designation [0.03%]
新的DQA1等位基因特异性抗体现货表位2D(外显子1编码氨基酸)同一P型中的等位基因的考虑因素
Danny Youngs,Paul Warner,Mary Gallagher et al.
Danny Youngs et al.
The majority of polymorphisms of the Human Leukocyte Antigen (HLA) proteins are clustered at the peptide binding domain (PBD), defined as the area coded by exon 2 and 3 for class I and exon 2 for class II. HLA alleles with the same amino ac...
Case Reports
Transplant immunology. 2018 Dec:51:32-39. DOI:10.1016/j.trim.2018.08.007 2018
Correlation of C3d donor specific antibodies and IgG MFI with positive complement dependent cytotoxicity and flow cytometry crossmatch in a cohort of HLA incompatible renal transplants: single centre experience [0.03%]
补体依赖的细胞毒性实验和流式微孔板交叉配型阳性的C3d供者特异性抗体和IgG MFI相关性分析:HLA不相容性肾移植队列报告
Adarsh Babu,Sunil Daga,Daniel A Mitchell et al.
Adarsh Babu et al.
B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy [0.03%]
接受传统免疫抑制治疗的移入猪动脉片植皮的狒狒的B细胞表型
Takayuki Yamamoto,Qi Li,Hidetaka Hara et al.
Takayuki Yamamoto et al.
Background: In the pig-to-baboon artery patch model with no immunosuppressive therapy, a graft from an α1,3-galactosyltransferase gene-knockout (GTKO) pig elicits a significant anti-nonGal IgG response, indicating sensit...
Bone marrow mesenchymal stromal cells attenuate liver allograft rejection may via upregulation PD-L1 expression through downregulation of miR-17-5p [0.03%]
骨髓间充质干细胞通过下调miR-17-5p上调PD-L1表达从而减轻同种异体肝移植排斥反应
Qiangxing Chen,Rou Zhou,Yingcai Zhang et al.
Qiangxing Chen et al.
Studies have reported that bone marrow mesenchymal stem cells (BMSCs) play an important role in immune regulation after organ transplantation. Some of the BMSC-mediated regulatory mechanisms are related to PD-L1 expression. However, the reg...
Sepsis is associated with lack of monocyte HLA-DR expression recovery without modulating T-cell reconstitution after lung transplantation [0.03%]
肺移植术后败血症与单核细胞HLA-DR表达缺乏恢复,但不调节T细胞重建
Julie Alingrin,Benjamin Coiffard,Julien Textoris et al.
Julie Alingrin et al.
Background: Immunosuppressive strategy targets mainly adaptive immunity after solid organ transplantation. We assessed the influence of early post-operative sepsis on T cell and monocyte reconstitution in anti-thymocyte g...
Multiple-biomarkers provide powerful prediction of early acute renal allograft rejection by combination of serum fractalkine, IFN-γ and IP-10 [0.03%]
多重生物标志物联合血清 fractalkine、IFN-γ 和IP-10预测早期急性肾移植排异反应
Cui-Xiang Xu,Bin-Ya Shi,Zhan-Kui Jin et al.
Cui-Xiang Xu et al.
Biomarkers are urgently required for predicting rejection so that anti-rejection treatment can be taken early to protect the allograft from irreversible damage. We hypothesized that the combination of circulating fractalkine, IFN-γ and IP-...