Anti-perlecan antibodies and acute humoral rejection in hypersensitized patients without forbidden HLA specificities after kidney transplantation [0.03%]
非禁忌HLA特异性肾移植高致敏受者的抗perlecan抗体和急性体液排斥反应
Laura Riesco,Juan Irure,Emilio Rodrigo et al.
Laura Riesco et al.
Background: The improvement in the definition of serum anti-HLA antibodies (HLA-Abs) profiles after Luminex-assay implementation in transplant patients follow-up is clear. This success has permitted the development of hyp...
Clinical use of an immune monitoring panel in liver transplant recipients: A prospective, observational study [0.03%]
肝移植受者免疫监测量表的临床应用：一项前瞻性观察研究
Lorenzo Iovino,Riccardo Taddei,Maria Lucia Bindi et al.
Lorenzo Iovino et al.
Immunosuppressive therapy greatly contributed to making liver transplantation the standard treatment for end-stage liver diseases. However, it remains difficult to predict and measure the efficacy of pharmacological immunosuppression. There...
Observational Study
Transplant immunology. 2019 Feb:52:45-52. DOI:10.1016/j.trim.2018.11.001 2019
Sequential monitoring of TIM-3 mRNA expression in blood and urine samples of renal transplant recipients [0.03%]
肾移植受者血液和尿液样本中TIM-3 mRNA的序贯监测
Sanaz Keshavarz Shahbaz,Mehri Barabadi,Pedram Ahmadpour et al.
Sanaz Keshavarz Shahbaz et al.
Background: T cell immunoglobulin and mucin domain 3 (TIM-3), as a co-inhibitory receptor expressed on Th1, Th17, CD8T, FoxP3 + Treg and innate immune cells, plays an important role in suppression of T cell-mediated immun...
Changes in serum KL-6 levels are associated with the development of chronic lung allograft dysfunction in lung transplant recipients [0.03%]
血清KL-6水平变化与肺移植受者的慢性移植物肺功能障碍发病相关性研究
V Bessa,F Bonella,S Ohshimo et al.
V Bessa et al.
Chronic lung allograft dysfunction (CLAD) remains a leading cause of death after lung transplantation. KL-6 is a reliable biomarker for various interstitial lung diseases and levels are increased in lung transplant recipients with versus wi...
Accuracy of the median channel shift in the flow cytometry for predicting complement dependent cytotoxicity crossmatching in kidney transplant candidates [0.03%]
流式细胞仪中位通道移的准确性在预测肾移植候选人的补体依赖性细胞毒性交叉配型中的应用
Priscila de Moraes,Iara Fagundes,Jacqueline Moraes Cardone et al.
Priscila de Moraes et al.
Crossmatching either by complement-dependent cytotoxicity (CDC) and/or by flow cytometry (FCXM) are routinely used for assessing anti-HLA donor antibodies before kidney transplantation. FCXM has demonstrated greater sensitivity and many tra...
Pretransplant angiotensin II type 1-receptor antibodies point to an increase in renal graft sub-intimal fibrosis in living- donor kidney transplant recipients [0.03%]
移植前血管紧张素II型1-受体抗体表明活体供者的肾脏移植接受者亚 intim 化纤维化增加
Alberto González-Almada,José M Arreola-Guerra,José Argenis López-Sánchez et al.
Alberto González-Almada et al.
The association between anti-AT1Rabs and microvascular injury observed in antibody-mediated rejection has been described in kidney graft Biopsies (KGBx). Methods: ...
Observational Study
Transplant immunology. 2019 Jun:54:1-8. DOI:10.1016/j.trim.2018.10.003 2019
Sara Assadiasl,Abbas Shahi,Saeedeh Salehi et al.
Sara Assadiasl et al.
Interferon regulatory factors (IRFs) are implicated in regulating inflammatory responses to pathogens and alloantigens. Since transplantation is usually accompanied by ischemia reperfusion injury (IRI), acute and chronic rejections, as well...
HLA class II Eplet mismatch predicts De Novo DSA formation post lung transplant [0.03%]
供者特异性抗体新生成的预测因素——Ⅱ类HLA表位不匹配
Duncan C Walton,Linda Cantwell,Steven Hiho et al.
Duncan C Walton et al.
The use of algorithms such as HLAMatchmaker to redefine donor-recipient HLA matching is gaining increasing attention. Our research has previously demonstrated that higher HLA class II eplet mismatches correlated with the development of chro...
Donor IL-6 deficiency evidently reduces memory T cell responses in sensitized transplant recipients [0.03%]
捐赠者IL-6缺陷明显减少了移植受者的致敏记忆T细胞反应
Juntao Chen,Chen Liu,Baoqing Liu et al.
Juntao Chen et al.
Background: Resistance of tolerance induction in sensitized transplantation is mainly caused by generation of memory T cells. It is unknown whether alteration of graft niche such as level of pro-inflammatory cytokines can...
CMV specific T cell immunity predicts early viremia after liver transplantation [0.03%]
肝移植后特异性T细胞免疫预测早期病毒血症
Kyung-Hwa Shin,Hyun-Ji Lee,Chulhun L Chang et al.
Kyung-Hwa Shin et al.
Background: Cytomegalovirus (CMV) infection is one of the most important factors affecting liver transplant with direct and indirect effects. However, CMV disease after transplant remains poorly predicted. ...