Can the Toll-like receptors 4 expression in peripheral blood mononuclear cells help assess the effectiveness of immunosuppression and the chance of a future good renal transplant function? [0.03%]
外周血单个核细胞中 toll 样受体 4 的表达能帮助评估免疫抑制的有效性及未来移植物的良好功能吗？
Slawomir C Zmonarski,Katarzyna Madziarska,Tomasz Golebiowski et al.
Slawomir C Zmonarski et al.
Background: A small percentage of peripheral blood mononuclear cells (PBMCs) circulating during the kidney transplantation (KT) period remain in the blood long after transplantation. A part of the PBMCs penetrates the gra...
John Jeongseok Yang,Sang-Hyun Hwang,Dae-Hyun Ko et al.
John Jeongseok Yang et al.
Introduction: Chimerism is defined as coexistence of different cell lines in an individual. 46,XX/46,XY chimerism is very rare and exhibits broad range of clinical phenotypes. Most cases are detected at infancy or younger...
Case Reports
Transplant immunology. 2019 Apr:53:38-42. DOI:10.1016/j.trim.2018.12.004 2019
Detection of engraftment of donor-derived antibody producing cells in a lung transplant recipient by anti-cytomegalovirus IgG avidity test [0.03%]
用抗巨细胞病毒IgG亲和力检测鉴定移植后受者中移植物来源的抗体产生细胞的植入情况
Tetsuo Koshizuka,Yasushi Matsuda,Hirotoshi Suzuki et al.
Tetsuo Koshizuka et al.
Transplant recipients become immunocompromised through the use of immunosuppressive therapy to prevent allograft rejection. These recipients readily experience human cytomegalovirus (CMV) infection or reactivation. Therefore, CMV represents...
Effects of recombinant thrombomodulin therapy and soluble human leukocyte antigen-G levels during hematopoietic stem cell transplantation [0.03%]
重组血栓调节蛋白治疗和可溶性人白细胞抗原-G水平对造血干细胞移植的影响
Shosaku Nomura,Tomoki Ito,Yuta Katayama et al.
Shosaku Nomura et al.
Background: Conditioning chemotherapies for hematopoietic stem cell transplantation (HSCT), especially those that include total body irradiation, can result in serious complications such as graft-versus-host disease (GVHD...
The prevention of tracheal graft occlusion using pioglitazone: A mouse tracheal transplant model study [0.03%]
吡格列酮预防气管移植后再狭窄的实验研究
Takao Shigenobu,Takashi Ohtsuka,Masayuki Shimoda
Takao Shigenobu
Bronchiolitis obliterans (BO), which begins with lymphocytic bronchiolitis (LB), is the most serious manifestations of chronic rejection following lung transplantation. We have evaluated the effects of intraperitoneal administration of piog...
HMGB1 blockade significantly improves luminal fibrous obliteration in a murine model of bronchiolitis obliterans syndrome [0.03%]
阻断 HMGB1 显著改善支气管闭塞性综合征小鼠模型中的腔内纤维化封闭现象
Shinkichi Takamori,Fumihiro Shoji,Tatsuro Okamoto et al.
Shinkichi Takamori et al.
Background: Although high-mobility group box-1 (HMGB1), which is a nuclear protein, was reported to enhance the allogeneic responses in transplantation, the effect of HMGB1 on bronchiolitis obliterans syndrome (BOS) is un...
An enigmatic case of undiagnosed severe diarrhoea post living donor liver transplant [0.03%]
一起令人费解的严重腹泻原因不明的活体肝移植案例
Amey Sonavane,Sanjiv Saigal
Amey Sonavane
Graft versus Host Disease (GVHD) after orthotopic liver transplant (OLT), although rare, carries >80% mortality. Early diagnosis, prompt treatment, and aggressive supportive care are imperative to potentially reverse this otherwise fatal ai...
Case Reports
Transplant immunology. 2019 Jun:54:17-19. DOI:10.1016/j.trim.2018.11.004 2019
iTRAQ-based quantitative proteomic analysis reveals potential early diagnostic markers in serum of acute cellular rejection after liver transplantation [0.03%]
基于iTRAQ的定量蛋白质组学分析揭示肝移植后急性细胞排斥反应的潜在早期诊断标志物
Qi Jiang,Yawei Ru,Yang Yu et al.
Qi Jiang et al.
Liver transplantation (LT) is the most effective treatment method for advanced stage liver disease but acute cellular rejection (ACR) seriously affects the prognosis of LT. To discover novel diagnostic biomarkers of ACR after LT, Isobaric T...
A novel MyD88 inhibitor attenuates allograft rejection after heterotopic tracheal transplantation in mice [0.03%]
一种新型MyD88抑制剂可减轻小鼠异位气管移植后的移植物排斥反应
Min Yang,Gen Chen,Xue Zhang et al.
Min Yang et al.
Background: After lung transplantation, the major complication limiting the long-term survival of allografts is obliterative bronchiolitis (OB), characterized by chronic rejection. Innate immune responses contribute to th...
Regulatory effects of dermal papillary pluripotent stem cells on polarization of macrophages from M1 to M2 phenotype in vitro [0.03%]
皮肤乳头层多能干细胞通过调控巨噬细胞从M1表型向M2表型极化的作用效应体外实验研究
Meiying Li,Jiayi Xu,Xianglin Mei et al.
Meiying Li et al.
The M1:M2 macrophage ratio is important for spinal cord injury (SCI) repair. Bone marrow mesenchymal stem cells (BMSCs) can alter macrophage activation, promoting M1 to M2 macrophage conversion and SCI repair; however, clinical BMSC applica...