Prevalence of antibodies to lung self-antigens (Kα1 tubulin and collagen V) and donor specific antibodies to HLA in lung transplant recipients and implications for lung transplant outcomes: Single center experience [0.03%]
肺移植受者针对肺自体抗原（Kα1微管蛋白和胶原V）抗体及供者特异性HLA抗体的流行病学特征及其对肺移植结局的影响：单一中心经验
Usha Rao,Monal Sharma,Thalachallour Mohanakumar et al.
Usha Rao et al.
Purpose: For patients with end stage lung disease, lung transplantation (LT) remains the only definitive treatment option. Long term survival post LT is limited by acute and chronic allograft dysfunction. Antibodies to lu...
Observational Study
Transplant immunology. 2019 Jun:54:65-72. DOI:10.1016/j.trim.2019.02.006 2019
Ming-Xiang Cheng,Jin-Zheng Li,Yong Chen et al.
Ming-Xiang Cheng et al.
Background: Vascular endothelial growth factor receptor-3 (VEGFR-3) / vascular endothelial growth factor -c (VEGF-C) signaling is reported to negatively regulate TLR4-triggered inflammation of macrophages. This study aims...
Ethylene carbodiimide-fixed donor splenocytes combined with cordycepin induce long-term protection to mice cardiac allografts [0.03%]
乙烯基碳二亚胺固定供者脾细胞结合虫草素诱导小鼠心脏异体移植的长期保护作用
Lai Xingqiang,Ning Fen,Yao Zhongpeng et al.
Lai Xingqiang et al.
Infusion of ethylene carbodiimide-fixed donor splenocytes (ECDI-SPs) is an effective method to induce donor-specific protection to allografts. However, the ischemia reperfusion (I/R) injury during transplant leads to abundant of pro-inflamm...
Increased splenic human CD4+:CD8+ T cell ratios, serum human interferon-γ and intestinal human interleukin-17 are associated with clinical graft-versus-host disease in humanized mice [0.03%]
人的脾脏中人类CD4+:CD8+T细胞比率升高，血液中的干扰素-γ和肠道中的白介素-17与临床移植物抗宿主病有关：用人源化小鼠进行的研究
Nicholas J Geraghty,Lisa Belfiore,Sam R Adhikary et al.
Nicholas J Geraghty et al.
Graft-versus-host disease (GVHD) is a frequent complication following allogeneic hematopoietic stem cell transplantation (HSCT) with current therapies limited to general immunosuppression. Humanized mouse models of GVHD are emerging as valu...
Pregnancy and donor-specific HLA-antibody-mediated rejection after liver transplantation: "Liaisons dangereuses"? [0.03%]
妊娠与肝脏移植后供者特异性HLA抗体介导的排斥反应："危险的关系"？
Jérôme Dumortier,Tomas Dedic,Domitille Erard-Poinsot et al.
Jérôme Dumortier et al.
Background: Risk factors for the development of anti-HLA antibodies include blood transfusion, organ transplantation, and pregnancy. Humoral rejection, mediated by donor-specific anti-HLA antibodies (DSA), has been studie...
Evaluation of the host immune response and functional recovery in peripheral nerve autografts and allografts [0.03%]
周围神经自体移植和同种异体移植中宿主免疫反应及功能恢复的评估
Kelly Cristine Santos Roballo,Jared Bushman
Kelly Cristine Santos Roballo
Allogeneic peripheral nerve (PN) transplants are an effective bridge for stimulating regeneration of segmental PN defects, but there are currently no detailed studies about the timeline and scope of the immunological response for PN allogra...
Comparative Study
Transplant immunology. 2019 Apr:53:61-71. DOI:10.1016/j.trim.2019.01.003 2019
Mannose binding lectin 2 gene polymorphisms in patients after renal transplantation with acute graft rejection [0.03%]
急性肾移植排异病人MBL2基因多态性分析
Michał Czerewaty,Maciej Tarnowski,Krzysztof Safranow et al.
Michał Czerewaty et al.
Mannose binding lectin 2 (MBL2) is one of the pattern-recognition soluble receptors and is responsible for complement activation via the lectin pathway, so it plays an important role in kidney transplantation. The aim of the study was to ex...
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats [0.03%]
罗格列酮对慢性肾移植失功大鼠的保护作用研究
Jin Deng,Yue Xia,Qin Zhou et al.
Jin Deng et al.
Background: Chronic renal allograft dysfunction (CRAD) is the main condition affecting the long-term survival of renal allografts. Rosiglitazone, which is a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist,...
Kinetics of antibody response to influenza vaccination in renal transplant recipients [0.03%]
肾移植受者接种流感疫苗后抗体反应的动力学规律研究
Shivaprakash Gangappa,Jens Wrammert,David Wang et al.
Shivaprakash Gangappa et al.
Annual vaccination is routinely used in organ transplant recipients for immunization against seasonal influenza. However, detailed analysis of the kinetics of vaccine-induced immune responses in this population is lacking. In this study, we...
Jon van Rood: The pioneer and his personal view on the early developments of HLA and immunogenetics [0.03%]
Jon van Rood：他在人类白细胞抗原和免疫遗传学早期发展方面的开拓者及其个人观点
Martine J Jager,Anneke Brand,Frans H J Claas
Martine J Jager
A single observation in a patient with an unusual transfusion reaction led to a life-long fascination with immunogenetics, and a strong wish to improve the care for patients needing a transplantation. In 2017, Jon van Rood, one of the pione...