Profiles of B-cell subsets in immunologically stable renal allograft recipients and end-stage renal disease patients [0.03%]
免疫稳定肾移植受者和终末期肾脏病患者B细胞亚群的特征分析
Quan Zhuang,Hao Li,Meng Yu et al.
Quan Zhuang et al.
Background: Post-transplantation pharmacotherapies typically employ combinations of immunosuppressive agents that have been designed for targeted inhibition of T-cells and T-cell subsets. Studies of acute and chronic effe...
Comparative Study
Transplant immunology. 2020 Feb:58:101249. DOI:10.1016/j.trim.2019.101249 2020
The effect of a novel immunosuppressive drug, a PAK-2 inhibitor, on macrophage differentiation/polarization in a rat small intestinal transplantation model [0.03%]
一种新型免疫抑制药物PAK-2抑制剂对大鼠小肠移植模型中巨噬细胞分化/极化的影响
Tasuku Kodama,Akira Maeda,Pei-Chi Lo et al.
Tasuku Kodama et al.
Objective: PQA-18 (Prenylated quinolinecarboxylic acid-18) has been reported to be a novel immunosuppressant that attenuates the production of various cytokines, and the differentiation of macrophages by inhibiting PAK2. ...
FK506 combined with GM6001 prevents tracheal obliteration in a mouse model of heterotopic tracheal transplantation [0.03%]
他植气管移植小鼠模型中FK506联合GM6001预防移植物闭塞的实验研究
Yiqian Li,Ping Shu,Liang Tang et al.
Yiqian Li et al.
Background: Obliterative bronchiolitis (OB) is the major complication limiting the long-term survival of allografts after lung transplantation. In this study, we investigated the effect of tacrolimus (FK506) combined with...
Peripheral CD19+CD24highCD38high B-regulatory cells in lung transplant recipients [0.03%]
肺移植受者中的外周CD19+CD24highCD38high B-调节细胞
Davide Piloni,Monica Morosini,Sara Magni et al.
Davide Piloni et al.
Background: The role of CD19+CD24highCD38high B-regulatory cells in solid-organ Transplant (Tx) in acceptance are still scarce. In previous studies on kidney transplant recipients may suggest a protective role of this cel...
Human CTLA4-Ig therapy can give false-positive anti-pig antibody results in primates after xenotransplantation [0.03%]
人源CTLA4-Ig免疫吸附法可假阳性升高灵长类动物移植前抗猪抗体滴度
Qi Li,Takayuki Yamamoto,Hayato Iwase et al.
Qi Li et al.
Background: Measurement of serum anti-pig antibodies is an important parameter in immune monitoring after pig-to-nonhuman primate xenotransplantation. Pig aortic endothelial cells (pAECs) are commonly used for this purpos...
Negative impact of recipient SPRED2 deficiency on transplanted lung in a mouse model [0.03%]
受者SPRED2缺陷对小鼠移植肺的负面影响
Kohei Hashimoto,Masaomi Yamane,Seiichiro Sugimoto et al.
Kohei Hashimoto et al.
Ischemia-reperfusion injury (IRI) after lung transplantation mainly contributes to the development of primary graft dysfunction. The Sprouty-related EVH1-domain-containing (SPRED) protein family inhibits the mitogen activated protein kinase...
The effect of oral melatonin on renal ischemia-reperfusion injury in transplant patients: A double-blind, randomized controlled trial [0.03%]
口服褪黑素对移植患者肾缺血再灌注损伤影响的双盲随机对照试验
Fatemeh Panah,Amir Ghorbanihaghjo,Hassan Argani et al.
Fatemeh Panah et al.
Background: One of the important factors in the occurrence of acute kidney injury (AKI) among renal transplant patients (RTPs) is ischemia reperfusion injury (IRI). The current study aimed at determining the anti-inflamma...
Randomized Controlled Trial
Transplant immunology. 2019 Dec:57:101241. DOI:10.1016/j.trim.2019.101241 2019
Suppressor of cytokine signaling genes in renal transplant receivers: Association with transplant fate [0.03%]
细胞因子信号抑制基因与肾移植结局的关系研究
Mohsen Nafar,Shiva Kalantari,Mir Davood Omrani et al.
Mohsen Nafar et al.
Suppressor of cytokine signaling (SOCS) proteins have acknowledged roles in regulation of immune responses. Moreover, their role in the evolution of allograft rejection is being elucidated. In the current investigation, we measured transcri...
Suppressor of cytokine signaling genes in renal transplant receivers: Association with transplant fate [0.03%]
细胞因子信号抑制基因与肾移植结局之间的关系
Mohsen Nafar,Shiva Kalantari,Mir Davood Omrani et al.
Mohsen Nafar et al.
Suppressor of cytokine signaling (SOCS) proteins have acknowledged roles in regulation of immune responses. Moreover, their role in the evolution of allograft rejection is being elucidated. In the current investigation, we measured transcri...
Immunoglobulin abnormalities in 1677 solid organ transplant recipients. Implications for posttransplantation follow-up [0.03%]
1677例器官移植受者免疫球蛋白异常的临床分析及移植后的随访意义
Peter Sečník Jr,Antonín Jabor,Petra Lavríková et al.
Peter Sečník Jr et al.
Background: Posttransplant lymphoproliferative disorder (PTLD) is a severe complication of solid organ transplantation (SOT). However, there is no consensus on PTLD screening methods. Gammopathies (GP), which occur in 10-...