Forty years of kidney transplantation: Insights into malignancies at a single center in Latin America [0.03%]
肾脏移植40年：拉丁美洲一家医疗中心对癌症的研究见解
Pilar Musalem,Carolina Sáez-Vera
Pilar Musalem
Background: Kidney transplantation is the optimal therapy for end-stage kidney disease (ESKD), but lifelong immunosuppression increases malignancy risk, a major cause of mortality in transplant recipients. This study eval...
Decreased circulating CD39+ regulatory T cell frequencies following non-traumatic brain death [0.03%]
非创伤性脑死亡后循环CD39+调节T细胞频率降低
Sedighe Poursaleh Amiri,Fattah Sotoudeh Nejad,Maryam Karamigolbaghi et al.
Sedighe Poursaleh Amiri et al.
Background and purpose: Regulatory T cells (Tregs) are thought to modulate immune responses during Brain death (BD), However findings on their role remain controversial. This study aimed to assess the frequency of circula...
Swertianolin regulates immunosuppression of myeloid suppressor cells in septic mice by inhibiting NF-κB and P38 signaling [0.03%]
Swertianolin通过抑制NF-κB和P38信号调节败血症小鼠的髓源性抑制细胞免疫抑制作用
Haoran Tang,Chen Liao,Lingling Wang et al.
Haoran Tang et al.
Background: Swertianolin is one of the main components of Gentianaceae Swertia plants, a traditional Chinese medicine used for the treatment of infection, fever, viral hepatitis, and pneumonia. An expansion of myeloid-der...
Mycobacterium haemophilum diagnosed via Karius test in a heart transplant recipient: A case report [0.03%]
通过Karius检测在心脏移植受者中诊断出喜热嗜血分枝杆菌病例报告
Zachary Malaussena,Michelle Lippincott,Francesca Dimou
Zachary Malaussena
Background: Mycobacterium haemophilum is a rare, slow-growing nontuberculous mycobacterium known to cause infections primarily in immunocompromised individuals. M. haemophilum infections typically present as skin and soft...
MicroRNAs in transplant rejection: Emerging roles in immune regulation and applications [0.03%]
microRNA在移植排斥中的作用：免疫调节和应用中的新兴角色
Shaochen Yu,Jian Lu
Shaochen Yu
Organ transplantation is the only effective treatment for patients with end-stage organ failure. Although modern immunosuppressive protocols are very effective and improve quality of life, there is still a need for improvements to eliminate...
Comprehensive up-to-date analysis on TCRαβ/CD19-depleted hematopoietic stem cell transplantation in pediatric hematological malignancies [0.03%]
TCRαβ/CD19剔除造血干细胞移植治疗儿童血液系统恶性肿瘤的全面研究进展
Hussien Ahmed H Abdelgawad,Heba Aboeldahab,Mohamed Mohamed Belal et al.
Hussien Ahmed H Abdelgawad et al.
This meta-analysis assesses the efficacy of TCRαβ+/CD19+ depleted hematopoietic stem cell transplantation (HSCT) in pediatric patients with hematological malignancies, bridging the gap in the heterogeneous results of published studies. We...
Ahmad Afyouni,Jana Kotaich,Sara Sarout et al.
Ahmad Afyouni et al.
Background: Immunotherapy is the concept of leveraging the immune system to treat diseases. Developing countries, including the Arab countries, have continued to lag in terms of biomedical research compared to other natio...
Impact of anti-HLA antibodies screening techniques on waiting time on the waiting list and kidney transplant outcomes [0.03%]
抗HLA抗体筛查技术对等待名单上等候时间和肾移植结果的影响
López-Pérez Juan,Villanego Florentino,Mazuecos Auxiliadora et al.
López-Pérez Juan et al.
Background: Differences in sensitivity and specificity between the techniques used for the detection of anti-HLA antibodies before kidney transplantation (KT) can lead to contradictory results that influence patients' man...
A lectin affinity plasmapheresis device removes extracellular vesicles and microRNAs from renal perfusates following controlled oxygenated rewarming of discarded donor kidneys [0.03%]
一种凝集素亲和力血浆分离装置可从控制供体肾脏的氧气复温后的肾灌注液中去除细胞外囊泡和microRNAs
Rosalia de Necochea Campion,Miguel Pesqueira,Paul Vallejos et al.
Rosalia de Necochea Campion et al.
Kidney transplantation is considered the benchmark treatment for end-stage kidney disease patients, yet the scarcity of suitable kidneys poses a significant hindrance for patients and healthcare providers. One approach is to extend the crit...
Prophylactic use of eculizumab for ABO-blood type incompatible kidney transplantation with extremely high ABO-blood type antibody titer: A two case report [0.03%]
埃库珠单抗在极高ABO血型抗体滴度下的ABO血型不合肾移植中的预防性使用：两例病例报告
Ayaka Mitomo,Kazunari Tanabe,Suguru Muraoka et al.
Ayaka Mitomo et al.
We report two cases of ABO-incompatible living-donor kidney transplantation (ABOi KT) performed in patients with exceptionally high ABO antibody titers. Both donor and recipient refused blood transfusions for religious reasons, limiting the...