Free light chain and intact immunoglobulin abnormalities in heart transplant recipients: Two year follow-up timelines and clinical correlations [0.03%]
心脏移植受者中轻链和完整免疫球蛋白异常的两年随访时间及临床相关性研究
Peter Sečník Jr,Petra Lavríková,Lenka Hošková et al.
Peter Sečník Jr et al.
Objectives: To assess the timelines of serum free light chain (sFLC) concentrations and the kappa/lambda light chain (K/L) ratio in heart transplant (HTX) recipients. To analyze the performance of serum protein electropho...
Assignment of C1q-binding HLA antibodies as unacceptable HLA antigens avoids positive CDC-crossmatches prior to transplantation of deceased donor organs [0.03%]
将C1q结合性HLA抗体分配为不可接受的HLA抗原可避免在移植供体器官前产生CDC阳性交联匹配现象
David Juhl,Matthias Marget,Michael Hallensleben et al.
David Juhl et al.
Soon, a virtual crossmatch shall replace the complement-dependent cytotoxicity (CDC) allocation crossmatch in the Eurotransplant region. To prevent positive CDC-crossmatches in the recipient centre, careful definition of unacceptable antige...
ASP0028 in combination with suboptimal-dose of tacrolimus in Cynomolgus monkey renal transplantation model [0.03%]
新型低剂量他克莫司联合ASP0028在食蟹猴肾移植模型中的应用研究
Hao Dun,Lijun Song,Anlun Ma et al.
Hao Dun et al.
FTY720, a S1P-receptor modulator, has shown to be effective in several transplant and autoimmune disease models, via modulating lymphocyte homing into secondary lymphoid organs (SLOs), and thereby reducing these cells in peripheral blood. A...
Comparative Study
Transplant immunology. 2017 Feb:40:57-65. DOI:10.1016/j.trim.2017.01.002 2017
Challenge of ex vivo-stimulated CD4+CD25+ regulatory T cell-mediated alloantigen-specific immunosuppression by murine cardiac transplantation [0.03%]
小鼠心脏移植中体外刺激的CD4+CD25+调节T细胞介导的同种异体抗原特异性免疫抑制面临的挑战
Tomohide Hori,Shinji Uemoto,Kanako Saito et al.
Tomohide Hori et al.
Negative regulation of HLA-DR expression on endothelial cells by anti-blood group A/B antibody ligation and mTOR inhibition [0.03%]
抗ABO血型抗体诱导和mTOR抑制对血管内皮细胞HLA-DR表达的负向调控作用
Kenta Iwasaki,Yuko Miwa,Kazuharu Uchida et al.
Kenta Iwasaki et al.
Donor-specific antibody (DSA), particularly against HLA class II, is a major cause of chronic antibody-mediated rejection (CAMR) after transplantation, although ABO-incompatible kidney transplantation has recently demonstrated favorable gra...
IFNy+ and IFNy- Treg subsets with stable and unstable Foxp3 expression in kidney transplant recipients with good long-term graft function [0.03%]
在移植肾功能良好的受者中表达稳定和不稳定的FoxP3的IFNγ+和IFNγ-Tregs亚群
Karina Trojan,Christian Unterrainer,Mostafa Aly et al.
Karina Trojan et al.
Background: Treg are a heterogenous cell population. In the present study we attempted to identify Treg subsets that might contribute to stable and good long-term graft function. ...
Rapid and strong de novo donor-specific antibody development in a lung transplant recipient: Short communication/case report [0.03%]
快速且强烈的从头供者特异性抗体在肺移植受者中的发展：简报/病例报告
Andrew L Lobashevsky,Kevin M Rosner,John D May et al.
Andrew L Lobashevsky et al.
A 66-yo female patient (typed B*39:01, 44:02) underwent first left single lung transplant (typed B*81:01, 15:17) on 02/07/2016 with negative for DSA in current and historical samples. On 02/17/2016 strong de novo DSA (MFI=15,200, C1q+) to B...
Case Reports
Transplant immunology. 2017 Feb:40:17-21. DOI:10.1016/j.trim.2016.12.003 2017
Rieko Sakai,Etsuko Kitano,Akira Maeda et al.
Rieko Sakai et al.
Background: Pigs are frequently used as animal models for experiments in the surgical field, including allo- and xeno-transplantation. Regeneration studies, including studies dealing with human- and monkey-induced pluripo...
Repeated human leukocyte antigen mismatches in lung re-transplantation [0.03%]
反复的人类白细胞抗原不匹配在肺再移植中的影响
Wiebke Sommer,Michael Hallensleben,Fabio Ius et al.
Wiebke Sommer et al.
Background: The role of HLA-sensitization in the absence of detectable DSA in lung re-transplantation is unclear. Antigens of the second donor matching the HLA typing of the first donor are considered 'unacceptable', by s...
Association of genetic polymorphisms of angiopoietin-like 4 with severity of posttransplant proteinuria in kidney allograft recipients [0.03%]
血管生成素样蛋白4基因多态性与肾移植受者的蛋白尿的关系研究
Youngil Chang,Tariq Shah,Jaewook Yang et al.
Youngil Chang et al.
Background: Proteinuria is a hallmark of glomerular injury, and persistent proteinuria is associated with graft failure in kidney transplant patients. Recently, it is known that the level of circulating angiopoietin-like ...