The role of HLA-E polymorphism and soluble HLA-E isoform in recurrent reproductive failures and male infertility [0.03%]
人类白细胞抗原E多态性和可溶性人类白细胞抗原E同种型在反复生殖失败和男性不育中的作用
Agnieszka Tarnowska,Andrzej Wiśniewski,Julia Burnos et al.
Agnieszka Tarnowska et al.
Background: Human leukocyte antigen (HLA)-E as a non-classical HLA class I molecule interacting with NK and T cell receptors may activate or inhibit immune responses. These reactions can impact reproductive success becaus...
Sexual dimorphism in neutrophil function: Unveiling the discriminative nature of male and female neutrophils [0.03%]
中性粒细胞功能的性别二态性：揭示男性和女性中性粒细胞的本质区别
Richard F Kraus,Nina Doblinger,Michael A Gruber et al.
Richard F Kraus et al.
Background: Women and men are different on many biological levels. Mounting evidence is now recognized that even the immune system has some significant sex differences, which are mainly cell mediated. This study investiga...
Deferoxamine attenuates sepsis-induced liver injury by suppressing ferroptosis [0.03%]
去铁敏通过抑制铁死亡减轻脓毒症诱导的肝损伤
Haidan Zhang,Hongyao Li,Shixian Liu et al.
Haidan Zhang et al.
Background: The liver is among the organs most frequently damaged during sepsis, and sepsis-induced liver injury is an independent risk factor for early patient mortality. Ferroptosis has been implicated in sepsis-related...
A novel approach to poliovirus vaccine neurovirulence testing: development of an enhanced 4-level scoring system [0.03%]
一种新的脊髓灰质炎疫苗神经毒力检测方法：建立一个增强版的四级评分系统
Xi Wang,Yunguang Hu,Anguo Yin et al.
Xi Wang et al.
The ongoing promotion and administration of vaccines play a critical role in the global effort to eradicate poliovirus. The Monkey Neurovirulence Test (MNVT) is an essential method for evaluating the neurovirulence of viruses in both the Or...
Specific human antibodies against SARS-CoV-2 and monkeypox virus generated via a rapid construction and screening system [0.03%]
一种快速构建和筛选系统产生针对SARS-CoV-2和猴痘病毒的特异性人源抗体
Guanglei Gu,Jinhai Wang,Xiaoyun Hu et al.
Guanglei Gu et al.
Monoclonal antibodies are playing an increasingly important role in modern medicine. Human monoclonal antibodies have become a key focus in the development of monoclonal antibody therapeutics due to their safety. We developed an integrated ...
Changpu Yujin Tang mitigates tourette syndrome by enhancing mitophagy and suppressing NLRP3 inflammasome-mediated pyroptosis [0.03%]
昌蒲玉金汤通过增强线粒体自噬和抑制NLRP3炎性小体介导的焦亡治疗抽动症
Shuang Huang,Liwei Huang,Mengxue Li et al.
Shuang Huang et al.
Background: Changpu Yujin Tang (CPYJT) is an effective Chinese herbal compound for treating Tourette syndrome (TS). However, its precise molecular mechanisms remain to be fully elucidated. ...
Serum exosome smallRNA array analysis identifies 5'tiRNA-PheGAA and tRF-1-IleAAT as potential biomarkers for diagnosis of rheumatoid arthritis [0.03%]
血清外泌体小RNA阵列分析鉴定5'tiRNA-PheGAA和tRF-1-IleAAT为类风湿性关节炎诊断的潜在生物标志物
Yuanyuan Li,Meiling Xu,Nan Zhao et al.
Yuanyuan Li et al.
tRNA-derived small RNAs (tsRNAs) are a recently identified class of non-coding RNAs (ncRNAs) that exhibit aberrant expression in various diseases and are involved in multiple pathological processes. In this study, we isolated exosomes from ...
sgp130Fc alleviates cartilage degeneration and knee osteoarthritis by inhibiting IL-6 trans-signaling pathway [0.03%]
SGP130FC通过抑制IL-6旁路信号通路缓解软骨退变和膝关节炎
Chunrong He,Lingjie Tan,Chi Liang et al.
Chunrong He et al.
Background: Interleukin-6 (IL-6) trans-signaling plays a pivotal role in the pathogenesis and progression of osteoarthritis (OA), contributing to chronic intra-articular inflammation and cartilage degradation. Soluble gp1...
Corrigendum to "UMI-77 targets MCL-1 to activate mitophagy and ameliorate periodontitis in mice" [Immunobiology 230(5) (2025) 153108] [0.03%]
“UMI-77通过靶向MCL-1激活自噬改善小鼠牙周病”的勘误(免疫生物学230(5)(2025)153108)
Dalei Sun,Shu Ouyang,Xiaoxuan Xu et al.
Dalei Sun et al.
Published Erratum
Immunobiology. 2025 Sep 23:153120. DOI:10.1016/j.imbio.2025.153120 2025
Role and mechanism of METTL3 in fibrosis-associated signaling in CVB3-infected H9c2 cardiomyocytes through the lncRNA MEG3/c-MYC/SMAD2 axis [0.03%]
METTL3通过长链非编码RNA MEG3/c-MYC/SMAD2轴调控柯萨奇病毒诱导心肌细胞纤维化的机制研究
Lu Huang,Li Wang,Jiaojiao Guo et al.
Lu Huang et al.
Viral myocarditis (VMC) is an inflammatory disease of the heart muscle caused by viral infection and may lead to myocardial fibrosis. This study aims to investigate the role of METTL3 in myocardial fibrosis in VMC. METTL3 expression was int...