Preface to the special issue for the 30th International Complement Workshop Brisbane 2025 [0.03%]
第30届国际补体研讨会布里斯班2025专刊前言
Barbara E Rolfe,John D Lee,Trent M Woodruff
Barbara E Rolfe
This Immunobiology special issue commemorates the 30th International Complement Workshop, held for the first time in Australia. Reflecting the global reach of complement research, the Workshop brought together delegates from 24 countries an...
Attenuated S. typhimurium delivery of STAT3-siRNA and endostatin co-expression plasmids for immune and angiogenesis modulation in colorectal cancer [0.03%]
结肠直肠癌中调节免疫和抗血管生成的STAT3-siRNA及endostatin联合表达质粒的减毒S. typhimurium递送系统
Ai Cui,Wenyan Fan,Tengyi Huang et al.
Ai Cui et al.
Background: Colorectal cancer (CRC) is the third most common cancer in men and the second most common in women worldwide. Due to its high metastasis rate and poor prognosis, CRC is the leading cause of cancer-related deat...
The clinical value of combined assessment of inflammatory biomarkers and liver reserve function in predicting the 12-week prognosis of HBV-ACLF [0.03%]
炎症生物标志物联合肝储备功能评估预测HBV相关急性-on-慢性肝功能衰竭12周预后的临床价值分析
Ke Luo,Tianhuang Liu
Ke Luo
Background: Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) represents a serious clinical condition characterized by acute deterioration of liver function in patients with chronic liver disease. Prompt...
Copper regulates the expression of immune genes in microglial cells in vitro [0.03%]
铜通过体外实验调节小胶质细胞的免疫基因表达
Laura Craciun,Sandra E Muroy,Kaoru Saijo
Laura Craciun
Copper, a transition metal, plays crucial roles in various physiological functions, including those of the nervous and immune systems. Dysregulation of copper homeostasis is linked to several diseases, such as neurodegenerative diseases. Si...
Measuring mRNA expression level of viral genes, IRF3/7 and TLR7/8 during BK polyomavirus infection in kidney transplant recipients [0.03%]
肾移植受者中BK多瘤病毒感染期间病毒基因、IRF3/7和TLR7/8的mRNA表达水平测定
Amin Zahmatkesh,Ramin Yaghobi,Ilnaz Sahragard et al.
Amin Zahmatkesh et al.
Background: Human BK polyomavirus (BKV) infection is a dangerous pathogenic factor in kidney transplant recipients (KTRs) due to the use of immunosuppressive drugs, which can cause damage to the transplanted kidneys after...
The expression of OX40 in CD4+ T cells and its association with hepatic fibrosis injury [0.03%]
CD4+T细胞OX40的表达及其与肝纤维化损伤的关系研究
YaLing Xu,WenNa Li,Yuan Li et al.
YaLing Xu et al.
Purpose: OX40 is a typical member of the co-stimulatory molecule family. The signals generated by its binding to OX40L have a synergistic effect, regulating T cell proliferation, differentiation, and influencing cytokine ...
Higher levels of urinary extracellular vesicles and immune mediators are related to acute infection severity during the post-COVID period [0.03%]
尿液胞外囊泡和免疫介导物的高水平与COVID后急性感染严重程度有关
Evelyn Maciel de Oliveira,Camila Carvalho,Natalia Fonseca do Rosário et al.
Evelyn Maciel de Oliveira et al.
Introduction: We investigated circulating and urinary inflammatory mediators and extracellular vesicles (EVs) in association with clinical and laboratory findings during the post-COVID-19 (coronavirus disease 2019) period...
NLRX1 as a novel therapeutic target: TRAF6-dependent inhibition of acute rejection in rat liver transplantation [0.03%]
NLRX1作为新治疗靶点的潜在作用：在大鼠肝移植中依赖TRAF6抑制急排反应
Zilun Lei,Tong Mou,Hao Chai et al.
Zilun Lei et al.
Recent research has underscored NLRX1's role in modulating hepatic immune responses. However, its function in Kupffer cells (KCs) during acute rejection (AR) post-liver transplantation is not well elucidated, and the mechanisms driving hepa...
Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection [0.03%]
溶血终末补体途径在小鼠重度疟疾感染模型中的致病作用
Tomoaki Kamiya,Yuki Miyasaka,Hangsoo Kim et al.
Tomoaki Kamiya et al.
Background: Malaria is an important and serious parasite-induced disease associated with severe anemia and multiple organ failure (MOF) that can be lethal in humans. We explored the contribution of the terminal pathway of...
The Role of WNT5A-mediated proteomic and phosphoproteomic regulatory networks in rheumatoid arthritis [0.03%]
WNT5A介导的蛋白质组和磷酸化蛋白质组调控网络在类风湿关节炎中的作用
Ping Jiang,Daxi Ma,Youji Jia et al.
Ping Jiang et al.
Objective: This study aims to investigate the role of the WNT5A signaling pathway in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) and uncover the impact of WNT5A on cellular function and signal transductio...