Mitochondrial activity related genes of mast cells identify poor prognosis and metastasis of ovarian cancer [0.03%]
与肥大细胞线粒体活性相关基因识别卵巢癌不良预后及转移
Xinghua Ma,Caryl Ligan,Shijia Huang et al.
Xinghua Ma et al.
The pro-tumorigenic or anti-tumorigenic role of tumor infiltrating mast cells (TIMs) in tumors depends not only on the type of cancer and the degree of tumor progression, but also on their location in the tumor bulk. In our investigation, w...
Retraction notice to "Increased levels of Th17 cells are associated with non-neuronal acetylcholine in COPD patients" [Immunobiology 219(5) (2014) 392-401] [0.03%]
撤稿通知“Th17细胞水平的升高与慢性阻塞性肺疾病患者非神经乙酰胆碱有关[免疫生物学杂志219卷5期（2014年）392-401页]"
Mirella Profita,Giusy Daniela Albano,Loredana Riccobono et al.
Mirella Profita et al.
Retraction of Publication
Immunobiology. 2024 Jun 28:152806. DOI:10.1016/j.imbio.2024.152806 2024
WIP1-mediated regulation of p38 MAPK signaling attenuates pyroptosis in sepsis-associated acute kidney injury [0.03%]
WIP1介导的p38MAPK信号调控在脓毒症相关急性肾损伤中的抗细胞焦亡作用
Yinhong Wang,Chenkai Cui,Weihao Zhao et al.
Yinhong Wang et al.
Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) is a serine/threonine phosphatase that plays a significant role in various physiological processes. However, the involvement of WIP1 in kidney remains unclear. Lipopolysaccharide (LPS) was ad...
Single-cell transcriptome analysis of macrophage subpopulations contributing to chemotherapy resistance in ovarian cancer [0.03%]
单细胞转录组分析卵巢癌化疗耐药相关巨噬细胞亚群
Xiaolin Zhong,Fei Zhang,Hongyang Xiao et al.
Xiaolin Zhong et al.
Background: Ovarian cancer, a fatal gynecological malignancy, is primarily managed through surgery and chemotherapy. However, a significant challenge arises as patients frequently experience relapse due to chemotherapy re...
APOE expression in papillary thyroid carcinoma: Influencing tumor progression and macrophage polarization [0.03%]
乳头状甲状腺癌中的APOE表达：影响肿瘤进程和巨噬细胞极化
Ronghua Huo,Ruhua Zhao,Ziwen Li et al.
Ronghua Huo et al.
Background: As metastatic papillary thyroid carcinoma becomes increasingly challenging to treat, immunotherapy has emerged as a new research direction. Tumor-associated macrophages (TAMs) influence the occurrence, invasio...
CD8 T lymphocytes from B-1 cell-deficient mice down-regulates fungicidal activity of macrophages challenged with E. Cuniculi [0.03%]
B-1细胞缺陷小鼠的CD8 T淋巴细胞下调了被E. cuniculi攻击的小胶质细胞的杀菌活性
Cristina Gabriela Nascimento de Oliveira,Elizabeth Cristina Perez,Anuska Marcelino Alvares-Saraiva et al.
Cristina Gabriela Nascimento de Oliveira et al.
Background: Encephalitozoon cuniculi is an opportunistic intracellular pathogen that establishes a balanced relationship with immunocompetent individuals depending on the activity of their CD8+ T cells lymphocytes. Howeve...
Increased inhibitory surface marker PD-1 expression in CD4+T cells and Th2+T cells in allergen-specific immunotherapy [0.03%]
过敏特异性免疫疗法中CD4⁺T细胞和Th2⁺T细胞上的抑制性表面标志物PD-1表达增多
Xueyan Jie,Dan Wang,Hongju Da et al.
Xueyan Jie et al.
Recent evidence has shown that T cell exhaustion is implicated in Allergen-specific Immunotherapy (AIT). However, how T cell exhaustion plays a role in AIT is far from clear. Our study aimed to investigate T cell exhaustion associated with ...
Acute lung injury is prevented by monocyte locomotion inhibitory factor in an experimental severe malaria mouse model [0.03%]
单核细胞运动抑制因子可预防严重疟疾小鼠模型中的急性肺损伤
Martha Jackeline Pérez-Vega,Gerardo Manuel Corral-Ruiz,Adrian Galán-Salinas et al.
Martha Jackeline Pérez-Vega et al.
Acute lung injury caused by severe malaria (SM) is triggered by a dysregulated immune response towards the infection with Plasmodium parasites. Postmortem analysis of human lungs shows diffuse alveolar damage (DAD), the presence of CD8 lymp...
Tumor-infiltrating lymphocytes, PD-L1, and MMR-deficiency combined characterization may identify subgroups of rectal cancer patients who would benefit from immunotherapy [0.03%]
肿瘤浸润淋巴细胞，PD-L1和MMR缺陷的综合表征可识别直肠癌患者中可能受益于免疫治疗的亚组病人
Alexandra Giatromanolaki,Christos Kavazis,Anastasia G Gkegka et al.
Alexandra Giatromanolaki et al.
Introduction: Mismatch repair deficiency, immunological fertility, and PD-L1 expression status are key histopathological and molecular features defining tumor responsiveness to immunotherapy and, eventually, prognosis. Th...
Targeting the dynamic transcriptional landscape of Treg subpopulations in pancreatic ductal adenocarcinoma: Insights from single-cell RNA sequencing analysis with a focus on CTLA4 and TIGIT [0.03%]
针对胰腺导管腺癌Treg亚群动态转录组的靶向研究：单细胞RNA测序分析中CTLA4和TIGIT相关性的见解
Adib Miraki Feriz,Arezou Khosrojerdi,Nafiseh Erfanian et al.
Adib Miraki Feriz et al.
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy that represents a significant challenge in cancer research and clinical management. In this study, we reanalyzed a published single-cell RNA sequencing (scRNA-seq) datase...