Cytokine profiling identifies an interaction of IL-6 and IL-1α to drive PSMA-PSA prostate clones [0.03%]
细胞因子谱分析鉴定出IL-6和IL-1α的相互作用可驱动PSMA-PSA前列腺克隆
Awatef Ben Jemaa,Yosra Bouraoui,Nawfel Ben Rais et al.
Awatef Ben Jemaa et al.
Background: Several PSMA-PSA prostate clones have been identified during prostate cancer progression; however, until now, their in situ inflammatory characteristics have remained unclear. ...
Mode of delivery and atopic phenotypes: Old questions new insights? A retrospective study [0.03%]
分娩方式与特应性表型：老问题新见解？一项回顾性研究
Caterina Cuppari,Sara Manti,Annamaria Salpietro et al.
Caterina Cuppari et al.
Background: To date studies on the relation between mode of delivery and atopic diseases in are controversial. Objective: The aim of th...
The staphylococcal surface-glycopolymer wall teichoic acid (WTA) is crucial for complement activation and immunological defense against Staphylococcus aureus infection [0.03%]
金黄色葡萄球菌细胞壁-teichoic酸（WTA）是激活补体和免疫防御金黄色葡萄球菌感染的关键因素
Kenji Kurokawa,Kazue Takahashi,Bok Luel Lee
Kenji Kurokawa
Staphylococcus aureus is a Gram-positive bacterial pathogen that is decorated by glycopolymers, including wall teichoic acid (WTA), peptidoglycan, lipoteichoic acid, and capsular polysaccharides. These bacterial surface glycopolymers are re...
Preface to the Special Issue for the XXVI International Complement Workshop [0.03%]
第26届补体工作坊专题问题的前言
Teizo Fujita,Nobutaka Wakamiya,Andrea J Tenner
Teizo Fujita
A novel infection- and inflammation-associated molecular signature in peripheral blood of myasthenia gravis patients [0.03%]
重症肌无力患者外周血感染及炎症相关分子标志物的筛查
Claudia Barzago,Josephine Lum,Paola Cavalcante et al.
Claudia Barzago et al.
Myasthenia gravis (MG) is a T-cell dependent autoimmune disorder of the neuromuscular junction, characterised by muscle weakness and fatigability. Autoimmunity is thought to initiate in the thymus of acetylcholine receptor (AChR)-positive M...
The collectins CL-L1, CL-K1 and CL-P1, and their roles in complement and innate immunity [0.03%]
补体和先天免疫中的集合簇CL-L1、CL-K1和CL-P1及其作用
Soren W K Hansen,Katsuki Ohtani,Nitai Roy et al.
Soren W K Hansen et al.
Both the complement system and collectins play important roles in our innate immune system. The collectins, which are characterized by their inclusion of a collagen-like region and a calcium-dependent carbohydrate recognition domain, are pa...
Human beta-defensin-2 and -3 enhance pro-inflammatory cytokine expression induced by TLR ligands via ATP-release in a P2X7R dependent manner [0.03%]
人β防御素-2和-3通过P2X7R依赖性ATP释放增强TLR配体诱导的促炎细胞因子表达
Daniela Wanke,Katrin Mauch-Mücke,Ernst Holler et al.
Daniela Wanke et al.
Our previous results indicate that HBD2 and HBD3 are chemotactic for a broad spectrum of leukocytes in a CCR6- and CCR2-dependent manner. In this study we report that pre-stimulation of primary human macrophages or THP-1 cells with HBD2 or ...
Rebecca Wiegner,Shinjini Chakraborty,Markus Huber-Lang
Rebecca Wiegner
The humoral serine proteases of the complement system and the coagulation system play central roles during the events of an inflammatory response. While the complement system confers immunoprotective and -regulatory functions, the coagulati...
Modeling complement-driven diseases in transgenic mice: Values and limitations [0.03%]
转基因小鼠的补体驱动疾病建模：价值与局限性
Yoshiyasu Ueda,Damodar Gullipalli,Wen-Chao Song
Yoshiyasu Ueda
Remarkable advances have been made over past decades in understanding the pathogenesis of complement-mediated diseases. This has led to development of new therapies for, and in some cases re-classification of, complement-driven diseases. Th...
Complement research in the 18th-21st centuries: Progress comes with new technology [0.03%]
18至21世纪的补体研究：新技术带来新进展
R B Sim,W Schwaeble,T Fujita
R B Sim
The complement system has been studied for about 120 years. Progress in defining this large and complex system has been dependent on the research technologies available, but since the introduction of protein chromatography, electrophoresis,...