Mechanistic insights into multi-metal toxicity interactions via plasmid DNA assay [0.03%]
基于质粒DNA的多金属毒性效应及其联合作用机制研究
Le Wang,Yushuang Yang,Jinjuan Li et al.
Le Wang et al.
Background: Heavy metals (Hg2⁺, Cd2⁺, Se4⁺, Zn2⁺) are widespread contaminants from industrialization and urbanization, posing severe ecological and human health risks due to persistence, bioaccumulation, and oxidative...
Hexavalent chromium exposure disrupts gut microbial structure and metabolic function in broiler chickens [0.03%]
六价铬暴露破坏肉鸡肠道微生物群结构和代谢功能
Qingwen Yang,Shanshan He,Bangquan Xiang et al.
Qingwen Yang et al.
Hexavalent chromium (Cr(VI)) is a pervasive environmental contaminant with well-documented toxicity, yet its impact on the gut microbiome remains poorly understood. This study investigated the effects of chronic dietary Cr(VI) exposure (37 ...
Transcriptomic response of human mesenchymal stromal cells exposed to Boron- and Molybdenum-substituted mesoporous bioactive glass nanoparticles [0.03%]
人源间质干细胞暴露于硼和钼掺杂的介孔生物活性玻璃纳米颗粒后的转录组响应
E Kunisch,Q Nawaz,T Walker et al.
E Kunisch et al.
Substitution of mesoporous bioactive glass nanoparticles (MBGNs; composition in mol%: 70 SiO2- 30 CaO) with therapeutically active ions such as Molybdenum (Mo) ions modulates their osteogenic properties. To overcome the limited pro-angiogen...
Early-life Co-exposure to fluoride and lead modifies the tissue distribution of essential and toxic trace elements [0.03%]
早期同时接触氟和铅会改变必需微量元素和有毒元素的组织分布
Natalia Macedo-Ribeiro,Jonas Tostes-Figueiredo,Maycon Lucas de Oliveira et al.
Natalia Macedo-Ribeiro et al.
Exposure to toxic metals such as lead (Pb) during early development is known to induce long-lasting physiological and neurological effects. However, little is known about how co-exposure to fluoride (F)-a common environmental and dietary el...
Serum hepcidin, iron stores, and iron availability are associated with cardiovascular health in Chinese children and adolescents: Basing on Life's Essential 8 metrics [0.03%]
基于生命八大指标的中国儿童和青少年血清铁调节素、铁储存及可利用性与心血管健康的相关性研究
Yueqin Zhou,Tianze Li,Lewei Zhu et al.
Yueqin Zhou et al.
Background: Iron metabolism has been associated with cardiovascular diseases, but its relationship with cardiovascular health (CVH) in childhood remains unclear. This study aimed to investigate the associations of iron pa...
Serum-to-hair Zn ratio as an index of zinc dyshomeostasis in HFpEF patients [0.03%]
HFpEF患者血清-头发锌比值与锌稳态失调的关系研究
Beata Krasińska,Tomasz Urbanowicz,Katarzyna Gabriel et al.
Beata Krasińska et al.
Background: Heart failure with preserved ejection fraction (HFpEF) is a systemic cardiometabolic syndrome characterized by chronic inflammation, oxidative stress, and endothelial dysfunction. Disturbances in trace element...
MicroRNA-221-3p targets the cell cycle regulator gene CDKN1B to suppress the cytotoxic effects of manganese in human pulmonary epithelial cells [0.03%]
微核糖核酸-221-3p通过靶向细胞周期调节基因CDKN1B抑制锰对人肺上皮细胞的毒性作用
Yokeshwaran Punniyasekaran,Harsha Akshaylal Pal,Sajal Dasmahapatra et al.
Yokeshwaran Punniyasekaran et al.
Background: Higher levels of manganese (Mn) are encountered in environmental and various occupational settings. Though Mn is an essential trace element required for many biological processes, chronic exposure to higher le...
Alleviating effects of baicalein on nickel-induced nephrotoxicity: Modulation of FOXO3a, PGC1-α/MFN2/DRP1 signaling cascades and the inflammatory responses [0.03%]
黄芩素对镍诱导的肾毒性的缓解作用：FOXO3a，PGC1-α/MFN2/DRP1信号通路及炎症反应的调节作用
Samir A Salama,Mohamed A M Ali,Afnan Bakhsh et al.
Samir A Salama et al.
Background: Despite its extensive industrial utility, nickel poses considerable health hazards to humans, in particular nephrotoxicity. The purpose of the present work was to assess the ability of baicalein to counteract ...
Health risk assessment of heavy metals in surrounding soils of chromite mines, Sabzevar, Iran [0.03%]
伊朗Sabzevar地区铬矿周围土壤重金属健康风险评估
Zahra SeyedAbadi,Hojat Emami,Fateme Naghizade Asl
Zahra SeyedAbadi
To assess the health risk of heavy metals in surrounding soils of chromite mine of Sabzevar in the northeast of Iran, soil samples around the chromite mine were taken and the concentrations of As, Cd, Co, Crtotal, Cr(VI), Cu, Fe, Mn, Pb, an...
Trace element composition and dietary exposure to Mn, Se, Mo, Cr, Co, Ni, and Li in the Cuban diet: Evidence from a Total Diet Study [0.03%]
基于膳食调查的古巴日常饮食中锰、硒、钼、铬、钴、镍和锂的人群膳食暴露及元素组成研究
Luisbel González,Yenisleidys Fernández-Guerrero,Ociel Muñoz-Fariña et al.
Luisbel González et al.
Trace elements in the diet originate from both geogenic and anthropogenic sources, and population exposure is determined by the combined effects of food composition and consumption patterns. This study applied an "as consumed" Total Diet St...