Reimagining cardiac surgery-the emerging role of prehabilitation and risk optimization [0.03%]
心脏手术的重塑——术前康复和风险优化的作用日益重要
Ludmil V Mitrev,Kathirvel Subramaniam,Mathew Patteril
Ludmil V Mitrev
Benjamin Shuker,Kathryn Essak,Mathew Patteril
Benjamin Shuker
Cardiac surgery carries substantial risks, particularly for an aging population with increased frailty, morbidity, and malnutrition. Prehabilitation and Enhanced Recovery After Surgery (ERAS) protocols are emerging as essential strategies t...
The role of biomarkers in the preoperative evaluation of cardiac surgical patients - A narrative review [0.03%]
心脏手术患者术前评估中生物标志物的作用——综述文章
Giles Coverdale,Matthew Camilleri,Mathew Patteril
Giles Coverdale
Background: Biomarkers play a crucial role in the preoperative assessment for cardiac surgery, aiding in risk stratification and evaluating comorbid diseases. ...
Magic in a bottle? A Focused review of factor concentrates for the intraoperative treatment of acquired coagulopathy - Fibrinogen concentrate, prothrombin complex concentrate, and recombinant activated factor VII [0.03%]
瓶装魔药？针对术中获得性凝血病治疗的浓缩因子药物集中回顾——纤维蛋白原，凝血酶复合物浓缩剂以及重组活化Ⅶ因子
Amir Zabida,Justyna Bartoszko,Keyvan Karkouti
Amir Zabida
Goal-directed administration of blood components including red cells, platelets, plasma, and factor concentrates plays a critical role in the management of intraoperative coagulopathy. Increasingly commonly used, purified and recombinant fa...
Sigismond Lasocki,Maëva Campfort,Maxime Leger et al.
Sigismond Lasocki et al.
Preoperative anemia is frequent and is associated with poor patient outcomes and higher transfusion rates. Perioperative blood transfusion is also associated with poor outcomes. These observations justify efforts to increase hemoglobin leve...
Adam Irving,Zoe K McQuilten
Adam Irving
Patient blood management is the umbrella term for a suite of initiatives designed to optimise blood product usage, minimise transfusion needs, and ensure appropriate and evidence-based transfusion practices. In this review we summarise publ...
Beth MacLean,Angela Weyand,Jayne Lim et al.
Beth MacLean et al.
Preoperative anemia affects one-third of patients undergoing major surgery and is associated with worse perioperative and postoperative outcomes; including length of hospital stay, allogeneic blood transfusion, morbidity, and mortality. Iro...
Does one unit really matter? Immunological effects of transfusion after universal leucodepletion [0.03%]
统一白细胞过滤后输血的免疫学效应——1单位血液有意义吗？
Arun Muthukumar,Juan Jose Guerra-Londono,Juan P Cata
Arun Muthukumar
Patients with cancer who receive allogeneic red blood cell transfusions are at risk of adverse reactions of varying severity. One of these reactions is immunomodulation, also known as transfusion-related immunomodulation. With the exact mec...
Ethan H Crispell,Jessica Trinh,Matthew A Warner
Ethan H Crispell
Postoperative anaemia is common among surgical patients. While often viewed as a benign condition, postoperative anaemia is neither inevitable nor harmless, being intricately linked with adverse outcomes. In this review, we summarize the pr...
How low can you go: Restrictive transfusion strategies in major surgery and physiological triggers [0.03%]
输血阈值越低越好吗？——重大手术的限制性输血策略及生理触发点
Gregory Mt Hare,Ahmad Alli,Helen Jiang et al.
Gregory Mt Hare et al.
Anemia and red blood cell transfusion are associated with adverse outcomes. Large randomized trials have demonstrated that restrictive transfusion strategies can safely reduce patient exposure to transfusion, forming a foundational pillar o...