Hypoxia/Reoxygenation Cycles, Reactive Oxygen Species and Succinate: A Mechanistic Framework for Apnea of Prematurity [0.03%]
早产儿呼吸暂停的机制框架：低氧/复氧循环、活性氧和琥珀酸
Vincent Joseph,Sofia Diego Diaz,Lina Ikhlef et al.
Vincent Joseph et al.
We review clinical observations and experimental data to examine the pathophysiological mechanisms by which apnea of prematurity and intermittent hypoxemia destabilizes respiratory control and might lead to neurodevelopmental disorders. Cli...
Luteolin increases baseline apneas and downregulates brainstem HIF in normoxia and chronic intermittent hypoxia [0.03%]
黄体 flavone 增加正常氧浓度和慢性间歇性缺氧下的基线呼吸暂停并下调脑干 HIF 表达
Bolival Apparecido Mendonça Junior,André Acácio Souza da Silva,Estela Sasso-Cerri et al.
Bolival Apparecido Mendonça Junior et al.
Hypoxia-inducible factor (HIF) is a key regulator of cellular adaptation to reduced oxygen availability. Chronic intermittent hypoxia (CIH), characterized by recurrent cycles of hypoxia and reoxygenation, promotes oxidative stress and activ...
Contrasting dynamic and peak exercise inspiratory constraints: Implications for dyspnoea and exercise tolerance in chronic obstructive pulmonary disease [0.03%]
慢性阻塞性肺疾病患者吸气限制的动态和峰值运动特征及其对呼吸困难和运动耐力的影响
Pedro Dal Lago,Danilo C Berton,Abed Hijleh et al.
Pedro Dal Lago et al.
Background: Exertional dyspnoea is linked to inspiratory constraints to tidal volume expansion in chronic obstructive pulmonary disease (COPD). Dynamic assessment of these constraints via serial inspiratory capacity (IC) ...
Oral breathing and oxygenation stability during wakefulness: Identifying an unresolved question in respiratory physiology [0.03%]
觉醒状态下的口腔通气与氧合稳定性：呼吸生理学中一个未解决的问题
Edson D F Oliveira,Thiago S Moreira
Edson D F Oliveira
Arterial oxygen saturation is traditionally interpreted using threshold-based paradigms in which physiological significance is primarily attributed to overt hypoxemia. However, evidence from sleep physiology and integrative respiratory rese...
Ventilatory Efficiency as a Sex-Dependent Determinant of Cardiorespiratory Fitness in Endurance Athletes: a cross-sectional study [0.03%]
有氧运动员心肺适能的性别差异性决定因素：横断面研究
Wagner Antides Ribeiro de Almeida Pina,Vitoria Luise Dos Santos Lourenço,Vinicius Ribeiro Dos Anjos et al.
Wagner Antides Ribeiro de Almeida Pina et al.
The relevance of ventilatory efficiency to aerobic performance in endurance athletes remains incompletely understood, particularly when potential sex-related differences are considered. This study investigated whether ventilatory efficiency...
Posture-related ventilation redistribution and associated factors in healthy subjects assessed by electrical impedance tomography [0.03%]
电容断层成像评估的健康受试者体位相关的通气重新分布及影响因素
Hirofumi Tsuji,Yukio Fujita,Kazuya Tanimura et al.
Hirofumi Tsuji et al.
Background: Ventilation distribution varies with body position because of gravitational loading, thoracic morphology, and respiratory muscle activity. Electrical impedance tomography (EIT) enables real-time assessment of ...
Intercostal electromyographic responses to multi-site chest wall vibration at an optimal frequency [0.03%]
多部位胸部振动刺激诱导肋间肌电活动的最佳频率响应研究
Masaaki Kobayashi,Kenta Kawamura,Yukako Setaka et al.
Masaaki Kobayashi et al.
Background: High-frequency mechanical vibration facilitates respiratory muscle activity via muscle spindle afferents. Although synchronised multi-site chest wall vibration enhances ventilation, the associated intercostal ...
Slower cycling cadence results in a reduction in the V̇O₂ slow component without changes in performance fatigability [0.03%]
较低的骑行踏频可降低摄氧量慢速组件而不会改变性能疲劳度
Renato Aparecido Corrêa Caritá,Camila Coelho Greco,Benedito Sérgio Denadai
Renato Aparecido Corrêa Caritá
This study investigated the fatigue hypothesis of the V̇O₂ slow component (V̇O₂SC), specifically whether performance fatigability is a necessary condition for the development of the V̇O₂SC during high-intensity cycling exercise. Nine ...
Weighted Gene Co-expression Network Analysis of Early-Life PM₂.₅-Exposed Lung Transcriptome Identifies Key Gene Modules and Hub Genes Associated with Developmental Programming of COPD Vulnerability [0.03%]
早年PM2.5暴露对肺转录组的加权基因共表达网络分析鉴定出关键模块和气道疾病的中心基因
S A Shittu,A S Alimi,S T Shittu
S A Shittu
Early-life exposure to fine particulate matter (PM₂.₅) is increasingly implicated in the developmental origins of chronic respiratory diseases; however, the underlying molecular mechanisms remain poorly defined. This study employed Weight...
Physiological responses during a maximal dry static breath-hold in a world champion freediver [0.03%]
世界冠军屏息潜水时的最大干式静止屏息生理反应
Gillian Schockaert,Sofie Engelborghs,Niels Bochanen et al.
Gillian Schockaert et al.
Few studies have described physiological and cardiac rhythm responses to maximal voluntary breath-holding in elite freedivers. This case study presents minute ventilation, PETO2, PETCO2, involuntary breathing movements (IBMs; surface electr...