Assembly of Hydrophobin class I from Agaricus bisporus produced different amyloid-like fibrils [0.03%] 来自双孢蘑菇的I类水合子装配产生不同类型的淀粉样纤维体
Jesús Rojas-Osnaya,Hugo Nájera Jesús Rojas-Osnaya
This work studied the extraction, purification, characterization, and assembly of hydrophobin class I from Agaricus bisporus (ABH4). The highest soluble protein concentration was obtained from the pinhead, the extraction and purification we...
Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design? [0.03%] NSP7的肽能够形成类淀粉样纤维:是artifct还是对药物设计的挑战?
Yuri Garmay,Aleksandr Rubel,Vladimir Egorov Yuri Garmay
•We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico •NSP7 (52–62) fragment is able to form amyloid-like fibrils•The possibility of using such a peptide as the basis for an antiviral drug is discussed ...