The role of proton-coupled electron transfer from protein to heme in dehaloperoxidase [0.03%]
质蛋白偶联电子转移在脱卤过氧化物酶中的作用
Mst Sharmin Aktar,Nikhila Kashyap Dhanvantari Madhuresh,Reza A Ghiladi et al.
Mst Sharmin Aktar et al.
At least two of the six methionine (Met) residues in dehaloperoxidase (DHP) are shown to act as electron donors in both autoreduction and protein-heme crosslinking. Autoreduction observed in the two isozymes, DHP-A and DHP-B, is explained b...
Incorporation of pyridoxal-5'-phosphate into the apoenzyme: A structural study of D-amino acid transaminase from Haliscomenobacter hydrossis [0.03%]
霍氏球鼓藻细菌D-氨基酸转氨酶的PLP催化的结构研究
Alina K Bakunova,Ilya O Matyuta,Mikhail E Minyaev et al.
Alina K Bakunova et al.
Pyridoxal-5'-phosphate (PLP)-dependent transaminases are key enzymes of amino acid metabolism in cells and remarkable biocatalysts of stereoselective amination for process chemistry applications. As cofactor-dependent enzymes, transaminases...
Ndufs4 knockout mice with isolated complex I deficiency engage a futile adaptive brain response [0.03%]
Ndufs4敲除小鼠的孤立复合物I缺乏激活徒劳的适应性脑反应
Melissa A E van de Wal,Cenna Doornbos,Janne M Bibbe et al.
Melissa A E van de Wal et al.
Paediatric Leigh syndrome (LS) is an early-onset and fatal neurodegenerative disorder lacking treatment options. LS is frequently caused by mutations in the NDUFS4 gene, encoding an accessory subunit of mitochondrial complex I (CI), the fir...
Phosphoproteome modulation by nucleoside diphosphate kinase affects photosynthesis & stress tolerance of Nostoc PCC 7120 [0.03%]
核苷二磷酸激酶通过调节磷酸化蛋白质组影响鱼腥藻7120的光合作用和胁迫耐受性
Anurag Kirti,Hema Rajaram
Anurag Kirti
Nucleoside diphosphate kinase (Ndk/NDK/NDPK) is known to possess pleiotropic functions, one of which is that as a protein kinase, and has been shown to be involved in stress tolerance in plants. To assess its role in the cyanobacterium Nost...
Investigation of adipocyte differentiation based on proteomics and intact N-glycopeptide modificationomics [0.03%]
基于蛋白质组和完整N-糖肽修饰组的脂肪细胞分化研究
Xin-Yu Li,Nuerbiye Nuermaimaiti,Xuanyu Meng et al.
Xin-Yu Li et al.
Objective: To investigate the role of N-glycosylation modification of proteins in adipocyte differentiation during the adipogenic process. Methods: ...
Structural insights into the mechanism underlying the dual cofactor specificity of glyoxylate reductase from Acetobacter aceti in the β-hydroxyacid dehydrogenase family [0.03%]
丙二酸脱氢酶家族中醋杆菌甘氨酸还原酶双辅助因子特异性的机制研究
Toma Rani Majumder,Takuya Yoshizawa,Masao Inoue et al.
Toma Rani Majumder et al.
The β-hydroxyacid dehydrogenase family exhibits diverse cofactor preferences: some enzymes favor NAD, others favor NADP, and a subset can utilize both NAD and NADPH. Glyoxylate reductase from Acetobacter aceti JCM 20276 (AacGR) exhibits a ...
Structure and functional studies of Avt1, a novel peptide from the sea anemone Aulactinia veratra [0.03%]
来源于海葵Aulactinia veratra的新肽Avt1的结构和功能研究
Renad A Albar,Hayden L Smith,Karoline Sanches et al.
Renad A Albar et al.
Sea anemones are a rich source of peptide toxins spanning a diverse range of biological activities, typically targeting proteins such as ion channels, receptors and transporters. These peptide toxins and their analogues are usually highly s...
Identification of dystrophin Dp71dΔ71-associated proteins in PC12 cells by quantitative proteomics [0.03%]
定量蛋白质组学鉴定PC12细胞中与Dp71dΔ71相关的蛋白
Coztli Azotla-Vilchis,Candelaria Merino-Jiménez,Emmanuel Ríos-Castro et al.
Coztli Azotla-Vilchis et al.
Dystrophin Dp71 is essential for the development of the nervous system. Its alteration is associated with intellectual disability. Different Dp71 isoforms are generated by alternative splicing; however, their functions have not been fully d...
Assembly of Hydrophobin class I from Agaricus bisporus produced different amyloid-like fibrils [0.03%]
来自双孢蘑菇的I类水合子装配产生不同类型的淀粉样纤维体
Jesús Rojas-Osnaya,Hugo Nájera
Jesús Rojas-Osnaya
This work studied the extraction, purification, characterization, and assembly of hydrophobin class I from Agaricus bisporus (ABH4). The highest soluble protein concentration was obtained from the pinhead, the extraction and purification we...
Serratiopeptidase exhibits antibiofilm activity through the proteolytic function of N-terminal domain and versatile function of the C-terminal domain [0.03%]
枯草杆菌肽通过N端结构域的蛋白水解功能和C端结构域的多种功能展现抗生物膜活性
Vishal Srivastava,Sheetal Bandhu,Shivam Mishra et al.
Vishal Srivastava et al.
Background: Serratiopeptidase, a serine protease traditionally used as an oral anti-inflammatory drug has been found to show antibiofilm action. Structurally, it comprises of two distinct domains; viz-the N-terminal catal...